Search Results - "Larsen, K. A"

Calibration of Failure Criteria for Bucket Foundations on Drained Sand under General Loading by Ibsen, L. B, Larsen, K. A, Barari, A

“…AbstractA new concept with respect to offshore wind turbines, the bucket foundation, is known in the oil and gas industry, although the load conditions for…”
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Efficacy of small‐molecule glycogen synthase kinase‐3 inhibitors in the postnatal rat model of tau hyperphosphorylation by Selenica, M‐L, Jensen, H S, Larsen, A K, Pedersen, M L, Helboe, L, Leist, M, Lotharius, J

“…Background and purpose: Glycogen synthase kinase‐3 (GSK‐3) affects neuropathological events associated with Alzheimeŕs disease (AD) such as…”
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Adaptive Plasticity Model for Bucket Foundations by Ibsen, L. B, Barari, A, Larsen, K. A

“…AbstractBased on experimental investigations, the literature proposes different methods for modeling the behavior and capacity of foundations subjected to…”
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Embedment Effects on Vertical Bearing Capacity of Offshore Bucket Foundations on Cohesionless Soil by Barari, A, Ibsen, L. B, Taghavi Ghalesari, A, Larsen, K. A

“…AbstractThis paper presents the results from a series of physical modeling and three-dimensional finite-element (FE) analyses in which the authors examined the…”
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Modified vertical bearing capacity for circular foundations in sand using reduced friction angle by Ibsen, L.B., Barari, A., Larsen, K.A.

“…Bucket foundations, which are large cylindrical structures that are open at the base and closed at the top, recently have attracted much attention in offshore…”
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Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression by Akalay, I, Tan, T Z, Kumar, P, Janji, B, Mami-Chouaib, F, Charpy, C, Vielh, P, Larsen, A K, Thiery, J P, Sabbah, M, Chouaib, S

“…The molecular basis for the resistance of tumor cells to cell-mediated cytotoxicity remains poorly understood and thus poses a major challenge for cancer…”
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Effect of Embedment on the Plastic Behavior of Bucket Foundations by Ibsen, L. B, Barari, A, Larsen, K. A

“…AbstractA series of comprehensive research and development projects has validated the novel concept of the bucket foundation as an alternative to piled…”
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How health-related quality of life assessment should be used in advanced colorectal cancer clinical trials by Bonnetain, F., Borg, C., Adams, R.R., Ajani, J.A., Benson, A., Bleiberg, H., Chibaudel, B., Diaz-Rubio, E., Douillard, J.Y., Fuchs, C.S., Giantonio, B.J., Goldberg, R., Heinemann, V., Koopman, M., Labianca, R., Larsen, A.K., Maughan, T., Mitchell, E., Peeters, M., Punt, C.J.A., Schmoll, H.J., Tournigand, C., de Gramont, A.

“…Traditionally, the efficacy of cancer treatment in patients with advance or metastatic disease in clinical studies has been studied using overall survival and…”
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Acquired chemoresistance of colorectal cancer (CRC) cells is accompanied by pro-invasive VEGF-signaling that can be attenuated by aflibercept by Larsen, A.K., van Dreden, P., Chibaudel, B., de Gramont, A., Gerotziafas, G., Thouroude, S.

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A need to simplify informed consent documents in cancer clinical trials. A position paper of the ARCAD Group by Bleiberg, H., Decoster, G., de Gramont, A., Rougier, P., Sobrero, A., Benson, A., Chibaudel, B., Douillard, J.Y., Eng, C., Fuchs, C., Fujii, M., Labianca, R., Larsen, A.K., Mitchell, E., Schmoll, H.J., Sprumont, D., Zalcberg, J.

“…In respect of the principle of autonomy and the right of self-determination, obtaining an informed consent of potential participants before their inclusion in…”
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Endomitosis of human megakaryocytes are due to abortive mitosis by VITRAT, N, COHEN-SOLAL, K, PIQUE, C, LE COUEDIC, J. P, NOROL, F, LARSEN, A. K, KATZ, A, VAINCHENKER, W, DEBILI, N

“…During megakaryocyte differentiation, the promegakaryoblast (immature megakaryocyte) increases its ploidy to a 2(x) DNA content by a poorly understood process…”
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Involvement of adenosine in retinal ischemia. Studies on the rat by Larsen, AK, Osborne, NN

“…The aim of this study was to determine whether adenosinergic agents can be used to slow down the changes seen in the rat retina after ischemia-reperfusion…”
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VUV and XUV reflectance of optically coated mirrors for selection of high harmonics by Larsen, K A, Cryan, J P, Shivaram, N, Champenois, E G, Wright, T W, Ray, D, Kostko, O, Ahmed, M, Belkacem, A, Slaughter, D S

“…We report the reflectance, ~1° from normal incidence, of six different mirrors as a function of photon energy, using monochromatic vacuum ultraviolet (VUV) and…”
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Dual mechanism of daunorubicin-induced cell death in both sensitive and MDR-resistant HL-60 cells by COME, M.-G, SKLADANOWSKI, A, LARSEN, A. K, LAURENT, G

“…Exposure of some acute myeloid leukaemia (AML) cells to daunorubicin leads to rapid cell death, whereas other AML cells show natural drug resistance. This has…”
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Selectivity of (3)H-MADAM binding to 5-hydroxytryptamine transporters in vitro and in vivo in mice; correlation with behavioural effects by Larsen, A K, Brennum, L T, Egebjerg, J, Sánchez, C, Halldin, C, Andersen, P H

“…1. Binding of the novel radioligand (3)H-2-(2-dimethylaminomethyl-phenylsulphanyl)-5-methyl-phenylamine ((3)H-MADAM) to the serotonin transporter (SERT) was…”
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In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent by Osborne, N.N, Cazevieille, C, Carvalho, A.L, Larsen, A.K, DeSantis, L

“…The aim of the study was to determine whether betaxolol is a neuroprotective agent and can therefore slow down the changes seen in the retina following…”
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DNA topoisomerase II and casein kinase II associate in a molecular complex that is catalytically active by Bojanowski, K, Filhol, O, Cochet, C, Chambaz, E.M., Larsen, A.K.

“…Immunoprecipitation of DNA topoisomerase II from yeast results in a preparation that contains casein kinase II; this suggests that the two proteins may…”
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Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II by MARKOVITS, J, LINASSIER, C, FOSSE, P, COUPRIE, J, PIERRE, J, JACQUEMIN-SABLON, A, SAUCIER, J.-M, LE PECQ, J.-B, LARSEN, A. K

“…Tyrosine phosphorylation plays a crucial role in cell proliferation and cell transformation which suggests that tyrosine kinase-specific inhibitors might be…”
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Modified expression for the failure criterion of bucket foundations subjected to combined loading by Larsen, K.A, Ibsen, L.B, Barari, A

“…Recently, various loading tests with small- and large-scale bucket foundations were performed on buckets of varying sizes, embedment ratios, and load paths…”
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Resistance of MCF7 human breast carcinoma cells to TNF-induced cell death is associated with loss of p53 function by CAI, Z, CAPOULADE, C, MOYRET-LALLE, C, AMOR-GUERET, M, FEUNTEUN, J, LARSEN, A. K, BRESSAC-DE PAILLERETS, B, CHOUAIB, S

“…We have investigated the relationship between the development of tumor resistance towards the cytotoxic action of tumor necrosis factor-alpha (TNF) and p53…”
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