Search Results - "Larsen, Jørgen N."

Legends of allergy and immunology: Henning Løwenstein by Würtzen, Peter A., Larsen, Jørgen N., Ipsen, Henrik

Get full text

Epitope Grafting, Re-creating a Conformational Bet v 1 Antibody Epitope on the Surface of the Homologous Apple Allergen Mal d 1 by Holm, Jens, Ferreras, Mercedes, Ipsen, Henrik, Würtzen, Peter A., Gajhede, Michael, Larsen, Jørgen N., Lund, Kaare, Spangfort, Michael D.

“…Birch-allergic patients often experience oral allergy syndrome upon ingestion of vegetables and fruits, most prominently apple, that is caused by antibody…”
Get full text

The Major Birch Allergen, Bet v 1, Shows Affinity for a Broad Spectrum of Physiological Ligands by Mogensen, Jesper E., Wimmer, Reinhard, Larsen, Jørgen N., Spangfort, Michael D., Otzen, Daniel E.

“…Bet v 1 is a 17-kDa protein abundantly present in the pollen of the White birch tree and is the primary cause of birch pollen allergy in humans. Its…”
Get full text

Patient related outcomes in a real life prospective follow up study: Allergen immunotherapy increase quality of life and reduce sick days by Petersen, Karin D, Kronborg, Christian, Larsen, Jørgen N, Dahl, Ronald, Gyrd-Hansen, Dorte

“…One fourth of the adult population in Europe suffer from respiratory allergy. Subcutaneous-allergen-specific-immunotherapy (SCIT) has long-term disease…”
Get full text

Particle Size Determination in Aluminum Hydroxide Suspensions Using Near-Infrared Transmittance Spectroscopy by Lai, Xuxin, Zheng, Yiwu, Ipsen, Henrik, Jacobsen, Susanne, Larsen, Jørgen N., Løwenstein, Henning, Søndergaard, Ib

“…A new method for particle size determination in polystyrene and aluminum hydroxide suspensions using near-infrared transmittance spectroscopy is described…”
Get full text

The metal binding site of the major house dust mite allergen Der p 1 by Meno, Kåre, Thorsted, Peter B., Ipsen, Henrik, Kristensen, Ole, Larsen, Jørgen N., Spangfort, Michael D., Gajhede, Michael, Lund, Kaare

“…Enzyme kinetic measurements on Der p 1 are usually performed in the presence of EDTA to prevent cation-facilitated inactivation of the active site cysteine…”
Get full text

X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy by Gajhede, Michael, Osmark, Peter, Poulsen, Flemming M, Ipsen, Henrik, Larsen, Jørgen N, van Neerven, R.J. Joost, Schou, Carsten, Løwenstein, Henning, Spangfort, Michael D

“…The three-dimensional structure of the major birch pollen allergen, the 17,500 M(r) acidic protein Bet v 1 (from the birch, Betula verrucosa), is presented as…”
Get full text

The Crystal Structure of Recombinant proDer p 1, a Major House Dust Mite Proteolytic Allergen by Meno, Kare, Thorsted, Peter B, Ipsen, Henrik, Kristensen, Ole, Larsen, Jorgen N, Spangfort, Michael D, Gajhede, Michael, Lund, Kaare

“…Allergy to house dust mite is among the most prevalent allergic diseases worldwide. Most house dust mite allergic patients react to Der p 1 from…”
Get full text

Dominating IgE-Binding Epitope of Bet v 1, the Major Allergen of Birch Pollen, Characterized by X-ray Crystallography and Site-Directed Mutagenesis by Spangfort, Michael D, Mirza, Osman, Ipsen, Henrik, van Neerven, R. J. Joost, Gajhede, Michael, Larsen, Jorgen N

“…Specific allergy vaccination is an efficient treatment for allergic disease; however, the development of safer vaccines would enable a more general use of the…”
Get full text

Allergy Vaccine Engineering: Epitope Modulation of Recombinant Bet v 1 Reduces IgE Binding but Retains Protein Folding Pattern for Induction of Protective Blocking-Antibody Responses by Holm, Jens, Gajhede, Michael, Ferreras, Mercedes, Henriksen, Anette, Ipsen, Henrik, Larsen, Jorgen N, Lund, Lise, Jacobi, Henrik, Millner, Anders, Wurtzen, Peter A, Spangfort, Michael D

“…Human type 1 immediate allergic response symptoms are caused by mediator release from basophils and mast cells. This event is triggered by allergens…”
Get full text

Dominant Epitopes and Allergic Cross-Reactivity: Complex Formation Between a Fab Fragment of a Monoclonal Murine IgG Antibody and the Major Allergen from Birch Pollen Bet v 1 by Mirza, Osman, Henriksen, Anette, Ipsen, Henrik, Larsen, Jorgen N, Wissenbach, Margit, Spangfort, Michael D, Gajhede, Michael

“…The symptoms characteristic of allergic hypersensitivity are caused by the release of mediators, i.e., histamine, from effector cells such as basophils and…”
Get full text

Major venom allergen of yellow jackets, Ves v 5: Structural characterization of a pathogenesis-related protein superfamily by Henriksen, Anette, King, Te P., Mirza, Osman, Monsalve, Rafaél I., Meno, Kåre, Ipsen, Henrik, Larsen, Jørgen N., Gajhede, Michael, Spangfort, Michael D.

“…Ves v 5 is one of three major allergens found in yellow‐jacket venom: phospholipase A1 (Ves v 1), hyaluronidase (Ves v 2), and antigen 5 (Ves v 5). Ves v 5 is…”
Get full text

Structure of the house dust mite allergen Der f 2: Implications for function and molecular basis of IgE cross-reactivity by Johannessen, Birthe R., Skov, Lars K., Kastrup, Jette S., Kristensen, Ole, Bolwig, Caroline, Larsen, Jørgen N., Spangfort, Michael, Lund, Kaare, Gajhede, Michael

“…The X-ray structure of the group 2 major allergen from Dermatophagoides farinae (Der f 2) was determined to 1.83Å resolution. The overall Der f 2 structure…”
Get full text

Determination of Adsorbed Protein Concentration in Aluminum Hydroxide Suspensions by Near-Infrared Transmittance Spectroscopy by Lai, Xuxin, Zheng, Yiwu, Jacobsen, Susanne, Larsen, Jørgen N., Ipsen, Henrik, Løwenstein, Henning, Søndergaard, IB

“…Analysis of aluminum hydroxide based vaccines is difficult after antigen adsorption. Adsorbed protein is often assessed by measuring residual unadsorbed…”
Get full text

High consistency in allergen composition of SQ house dust mite (HDM) tablet for sublingual immunotherapy (SLIT) by Henmar, Helene, Mikles, Andrew, Grosch, Karin, Larsen, Jorgen N.

“…Quality control included total IgE binding capacity by Centaur assay, major allergen determination by radial immuno diffusion; protein and antigen profile by…”
Get full text

Consistent composition and potency of freeze dried tablets for sublingual immunotherapy by Henmar, Helene, Sønderkær, Susanne, Nørby, Pernille H., Christensen, Lars H., Larsen, Jorgen N.

“…Release kinetics of individual allergen components from source materials differ, and the production process must be optimised individually for every source…”
Get full text

The blocking activity of birch pollen-specific immunotherapy-induced IgG4 is not qualitatively superior to that of other IgG subclasses by Ejrnaes, Anne M, Bodtger, Uffe, Larsen, Jørgen N, Svenson, Morten

“…Allergen-specific IgG antibodies induced by specific immunotherapy (SIT) interfere with the allergen–IgE interaction, and act as blocking antibodies in vitro…”
Get full text

Allergen nomenclature: a need for the scientific community by Larsen, Jørgen N

Get more information

Mutated major allergens for allergy vaccination by Spangfort, Michael D, Ipsen, Henrik, Lund, Kaare, Holm, Jens, Larsen, Jørgen N

Get full text

FACS-FAP: A novel method for detecting the influence of grass pollen immunotherapy on IgE-facilitated antigen presentation by Wachholz, PA, Neerven, RJJ Van, Kristensen, N, Larsen, Jørgen N, Till, Stephen, Durham, Stephen

Get full text