Search Results - "Larsen, Gary"
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Beyond New Public Governance: A Value-Based Global Framework for Performance Management, Governance, and Leadership
Published in Administration & society (01-05-2013)“…This article proposes a value-based model for performance management, governance, and public service leadership development. There are three distinguishing…”
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Long-Term Inhaled Corticosteroids in Preschool Children at High Risk for Asthma
Published in The New England journal of medicine (11-05-2006)“…Children whose parents have asthma and who begin to wheeze are at high risk for asthma. In this NIH-sponsored study, children who were two or three years old…”
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Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma
Published in Journal of allergy and clinical immunology (01-04-2009)“…Background Determination of the benefits and limitations of specific physiologic tests has not been well studied in long-term clinical pediatric trials…”
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Azithromycin or montelukast as inhaled corticosteroid–sparing agents in moderate-to-severe childhood asthma study
Published in Journal of allergy and clinical immunology (01-12-2008)“…Background Clinical trials in children with moderate-to-severe persistent asthma are limited. Objective We sought to determine whether azithromycin or…”
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Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing
Published in Journal of allergy and clinical immunology (01-12-2008)“…Background Acute wheezing illnesses in preschoolers require better management strategies to reduce morbidity. Objectives We sought to examine the effectiveness…”
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Characterization of within-subject responses to fluticasone and montelukast in childhood asthma
Published in Journal of allergy and clinical immunology (01-02-2005)“…Responses to inhaled corticosteroids (ICSs) and leukotriene receptor antagonists (LTRAs) vary among asthmatic patients. We sought to determine whether…”
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Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: The Pediatric Asthma Controller Trial
Published in Journal of allergy and clinical immunology (2007)“…Background More evidence is needed on which to base recommendations for treatment of mild-moderate persistent asthma in school-aged children. Objective The…”
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Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma
Published in Journal of allergy and clinical immunology (2006)“…Outcome data are needed to base recommendations for controller asthma medication use in school-aged children. We sought to determine intraindividual and…”
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Impulse oscillometry provides an effective measure of lung dysfunction in 4-year-old children at risk for persistent asthma
Published in Journal of Allergy and Clinical Immunology (01-08-2003)“…Background: Objective lung function measurements are routinely used to diagnose and manage asthma, but their utility for young children has not been defined…”
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Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children
Published in Journal of allergy and clinical immunology (01-11-2003)“…Exhaled nitric oxide (eNO) is a noninvasive test that measures airway inflammation. Insufficient information is available concerning correlations between eNO…”
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Spontaneous airway hyperresponsiveness in estrogen receptor-α-deficient mice
Published in American journal of respiratory and critical care medicine (15-01-2007)“…Airway hyperresponsiveness is a critical feature of asthma. Substantial epidemiologic evidence supports a role for female sex hormones in modulating lung…”
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Use of videography in the diagnosis of exercise-induced vocal cord dysfunction: A case report with video clips
Published in Journal of allergy and clinical immunology (01-06-2007)“…Because the patient was scheduled for competition to qualify for junior nationals within a few days of her initial evaluation, she was placed on a trial of…”
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Calcitonin gene-related peptide: role in airway homeostasis
Published in Current opinion in pharmacology (01-06-2004)“…The lung is an important source of sensory neuropeptides that modulate airway function in health and disease. Among these neuropeptides, calcitonin…”
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Regulation of Airway Hyperresponsiveness by Calcitonin Gene-related Peptide in Allergen Sensitized and Challenged Mice
Published in American journal of respiratory and critical care medicine (15-04-2002)“…Sensory neuropeptides are localized to airway nerves and endocrine cells in both human and animal species and may participate in the development of airway…”
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Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection
Published in American journal of physiology. Lung cellular and molecular physiology (01-04-2005)“…The mechanisms by which respiratory syncytial virus (RSV) infection causes airway hyperresponsiveness (AHR) are not fully established. We hypothesized that RSV…”
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Induction and regulation of nitric oxide synthase in airway epithelial cells by respiratory syncytial virus
Published in American journal of respiratory and critical care medicine (01-02-2001)“…In this study, we evaluated the effects of respiratory syncytial virus (RSV) infection on nitric oxide (NO) production in human airway epithelial cells. In…”
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Assessing respiratory function in young children: Developmental considerations
Published in Journal of allergy and clinical immunology (01-04-2005)“…The purpose of this review is to provide practitioners and clinical investigators with an update on methods of assessing respiratory function in young…”
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The Prevention of Early Asthma in Kids study: design, rationale and methods for the Childhood Asthma Research and Education network
Published in Controlled clinical trials (01-06-2004)“…Pediatric asthma remains an important public health concern as its prevalence and cost to the health care system is rising. In order to promote innovative…”
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Modulation of airway responses by prostaglandins in young and fully grown rabbits
Published in American journal of physiology. Lung cellular and molecular physiology (01-07-2007)“…Maturational changes have been noted in neurally mediated contractile and relaxant responses in airways from New Zealand White rabbits. In this study, we…”
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Neuropeptide release from airways of young and fully-grown rabbits
Published in Pediatric pulmonology (01-12-2006)“…Nerve growth factor (NGF), a neurotrophin that regulates neuronal development, enhances production of neuropeptides that control airway caliber including…”
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