Search Results - "Larsen, Flemming H"

Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes by Haxholm, Gitte W, Nikolajsen, Louise F, Olsen, Johan G, Fredsted, Jacob, Larsen, Flemming H, Goffin, Vincent, Pedersen, Stine F, Brooks, Andrew J, Waters, Michael J, Kragelund, Birthe B

“…Class 1 cytokine receptors regulate essential biological processes through complex intracellular signalling networks. However, the structural platform for…”
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Exploring the Solid-Form Landscape of Pharmaceutical Hydrates: Transformation Pathways of the Sodium Naproxen Anhydrate-Hydrate System by Raijada, Dhara, Bond, Andrew D., Larsen, Flemming H., Cornett, Claus, Qu, Haiyan, Rantanen, Jukka

“…ABSTRACT Purpose To understand the transformation pathways amongst anhydrate/hydrate solid forms of sodium naproxen and to highlight the importance of a…”
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13C NMR Chemical Shifts of Saccharides in the Solid State: A Density Functional Theory Study by Moustafa, Hadeel, Larsen, Flemming H., Madsen, Anders Ø., Sauer, Stephan P. A.

“…In this work we present a systematic, theoretical investigation of the 13C NMR chemical shifts for several mono-, di- and trisaccharides in the solid state…”
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Rhamnogalacturonan-I Based Microcapsules for Targeted Drug Release by Svagan, Anna J, Kusic, Anja, De Gobba, Cristian, Larsen, Flemming H, Sassene, Philip, Zhou, Qi, van de Weert, Marco, Mullertz, Anette, Jørgensen, Bodil, Ulvskov, Peter

“…Drug targeting to the colon via the oral administration route for local treatment of e.g. inflammatory bowel disease and colonic cancer has several advantages…”
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Interpreting the Disordered Crystal Structure of Sodium Naproxen Tetrahydrate by Bond, Andrew D, Cornett, Claus, Larsen, Flemming H, Qu, Haiyan, Raijada, Dhara, Rantanen, Jukka

“…The crystal structure of the tetrahydrate of the active pharmaceutical ingredient sodium naproxen is examined using single-crystal X-ray diffraction, supported…”
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Billion-Fold Enhancement in Sensitivity of Nuclear Magnetic Resonance Spectroscopy for Magnesium Ions in Solution by Gottberg, Alexander, Stachura, Monika, Kowalska, Magdalena, Bissell, Mark L., Arcisauskaite, Vaida, Blaum, Klaus, Helmke, Alexander, Johnston, Karl, Kreim, Kim, Larsen, Flemming H., Neugart, Rainer, Neyens, Gerda, Garcia Ruiz, Ronald F., Szunyogh, Daniel, Thulstrup, Peter W., Yordanov, Deyan T., Hemmingsen, Lars

“…β‐nuclear magnetic resonance (NMR) spectroscopy is highly sensitive compared to conventional NMR spectroscopy, and may be applied for several elements across…”
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Structural basis for the transformation pathways of the sodium naproxen anhydrate-hydrate system by Bond, Andrew D, Cornett, Claus, Larsen, Flemming H, Qu, Haiyan, Raijada, Dhara, Rantanen, Jukka

“…Crystal structures are presented for two dihydrate polymorphs (DH-I and DH-II) of the non-steroidal anti-inflammatory drug sodium (S)-naproxen. The structure…”
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High throughput prediction of chylomicron triglycerides in human plasma by nuclear magnetic resonance and chemometrics by Savorani, Francesco, Kristensen, Mette, Larsen, Flemming H, Astrup, Arne, Engelsen, Søren B

“…The lipid content of the chylomicrons is a key biomarker and risk factor of cardiovascular diseases and for the understanding of obesity. A high throughput…”
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Simulations of molecular dynamics in solid-state NMR spectra of spin-1 nuclei including effects of CSA- and EFG-terms up to second order by Larsen, Flemming H.

“…By numerical simulations MAS and QCPMG methods for acquiring spectra of spin-1 nuclei were compared in order to determine the most sensitive experiment for…”
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Sensitivity-Enhanced Quadrupolar-Echo NMR of Half-Integer Quadrupolar Nuclei. Magnitudes and Relative Orientation of Chemical Shielding and Quadrupolar Coupling Tensors by Larsen, Flemming H, Jakobsen, Hans J, Ellis, Paul D, Nielsen, Niels Chr

“…A novel approach to quadrupolar-echo (QE) NMR of half-integer quadrupolar nuclei in static powders is analyzed. By acquisition of the QE spectrum during a…”
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Structure and Biochemical Function of a Prototypical Arabidopsis U-box Domain by Andersen, Pernille, Kragelund, Birthe B., Olsen, Addie N., Larsen, Flemming H., Chua, Nam-Hai, Poulsen, Flemming M., Skriver, Karen

“…U-box proteins, as well as other proteins involved in regulated protein degradation, are apparently over-represented in Arabidopsis compared with other model…”
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Structure and hydration of the amylopectin trisaccharide building blocks-Synthesis, NMR, and molecular dynamics by Hansen, Peter I., Larsen, Flemming H., Motawia, Saddik M., Blennow, Andreas, Spraul, Manfred, Dvortsak, Peter, Engelsen, Søren B.

“…To gain insight into the molecular details and hydration of amylopectin, the five constituting trisaccharides have been chemically synthesized as their methyl…”
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Monitoring the stability of heparin: NMR evidence for the rearrangement of sulfated iduronate in phosphate buffer by Kozlowski, Aleksandra M., Yates, Edwin A., Roubroeks, Johannes P., Tømmeraas, Kristoffer, Larsen, Flemming H., Smith, Alan M., Morris, Gordon A.

“…Heparin, a major anticoagulant drug, comprises a complex mixture of motifs. Heparin is isolated from natural sources while being subjected to a variety of…”
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1H NMR spectra dataset and solid-state NMR data of cowpea (Vigna unguiculata) by Alves Filho, Elenilson G., Silva, Lorena M.A., Teofilo, Elizita M., Larsen, Flemming H., de Brito, Edy S.

“…In this article the NMR data from chemical shifts, coupling constants, and structures of all the characterized compounds were provided, beyond a complementary…”
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Quantitation of Protein Cysteine–Phenol Adducts in Minced Beef Containing 4‑Methyl Catechol by Arsad, Siti Suriani, Zainudin, Mohd Asraf Mohd, De Gobba, Cristian, Jongberg, Sisse, Larsen, Flemming H, Lametsch, René, Andersen, Mogens L, Lund, Marianne N

“…Thiol groups of cysteine (Cys) residues in proteins react with quinones, oxidation products of polyphenols, to form protein–polyphenol adducts. The aim of the…”
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Noncatalytic Direct Liquefaction of Biorefinery Lignin by Ethanol by Nielsen, Joachim B, Jensen, Anders, Madsen, Line R, Larsen, Flemming H, Felby, Claus, Jensen, Anker D

“…There is a growing interest in lignin valorization to biofuels and chemicals. Here, we propose a novel and simple noncatalytic process to directly liquefy…”
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Exciting Opportunities for Solid-State 95Mo NMR Studies of MoS2 Nano-structures in Materials Research from Low to Ultra-high Magnetic Field (35.2 T) by Jakobsen, Hans J., Bildsøe, Henrik, Bondesgaard, Martin, Iversen, Bo B., Brorson, Michael, Larsen, Flemming H., Gan, Zhehong, Hung, Ivan

“…Solid-state, natural-abundance 95 Mo NMR experiments of four different MoS 2 materials have been performed on a magnet B 0 = 19.6 T and on a new Series…”
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Fast measurement of phosphates and ammonium in fermentation-like media: A feasibility study by Pontius, Katrin, Praticò, Giulia, Larsen, Flemming H., Skov, Thomas, Arneborg, Nils, Lantz, Anna Eliasson, Bevilacqua, Marta

“…•Real-time monitoring of fermentation parameters is important for modern industries.•Analysis of phosphates and ammonium in a wide range of concentration…”
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Towards the role of metal ions in the structural variability of proteins: CdII speciation of a metal ion binding loop motif by Jancsó, Attila, Szunyogh, Dániel, Larsen, Flemming H, Thulstrup, Peter W, Christensen, Niels Johan, Gyurcsik, Béla, Hemmingsen, Lars

“…A de novo designed dodecapeptide (HS), inspired by the metal binding loops of metal-responsive transcriptional activators, was synthesized. The aim was to…”
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Solubilization of industrial grade plant protein by enzymatic hydrolysis monitored by vibrational and nuclear magnetic resonance spectroscopy: A feasibility study by Bevilacqua, Marta, Praticò, Giulia, Plesner, Johanne, Molloy, Maja, Skov, Thomas, Larsen, Flemming H.

“…Protein hydrolysates are of great interest in the food industry due to their nutritional and functional properties, but their use often implies solubilization…”
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