Search Results - "Larroquette, Mathieu"
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Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expression
Published in Nature cancer (01-08-2021)“…Only a minority of patients derive long-term clinical benefit from anti-PD1/PD-L1 monoclonal antibodies. The presence of tertiary lymphoid structures (TLS) has…”
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Immune checkpoint inhibitor rechallenge in patients who previously experienced immune-related inflammatory arthritis: a multicentre observational study
Published in Rheumatic & musculoskeletal diseases open (29-11-2023)“…ObjectiveAnother course of immune checkpoint inhibitors (ICIs) is often considered in patients with cancer progression and previous immune-related adverse…”
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New Insights into Adjuvant Therapy in Renal Cell Carcinoma: Is the Chapter of VEGF Inhibitors Definitely Closed?
Published in European urology (01-09-2021)“…Adjuvant therapy with antiangiogenic agents in locoregional renal cell carcinoma did not translate into a sufficient benefit and highlight the crucial role of…”
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Strategic treatment pause of first-line immune checkpoint inhibitor + VEGFR-tyrosine kinase inhibitor in patients with good or intermediate risk metastatic renal cell carcinoma (mRCC) in response at 1 year of treatment (SPICI-GETUG R05): A non-inferiority randomized clinical trial
Published in Journal of clinical oncology (01-02-2024)“…TPS487 Background: Treatment of mRCC consists of combination of either Immune Checkpoint Inhibitor (ICI)-Tyrosine Kinase Inhibitor (TKI) for all IMDC prognosis…”
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Combining immune checkpoint inhibitors with chemotherapy in advanced solid tumours: A review
Published in European journal of cancer (1990) (01-11-2021)“…The use of immune checkpoint inhibitors (ICIs), especially anti-programmed cell death 1 (PD1) and anti-programmed cell death ligand 1 (PD-L1), has changed…”
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Adjuvant therapy in renal cell carcinoma: Current knowledges and future perspectives
Published in Cancer treatment reviews (01-06-2021)“…•While approximately 70% of cases of renal cell carcinoma (RCC) are diagnosed at non-metastatic stage, effective adjuvant treatments are urgently needed to…”
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Gastrointestinal metastases in renal cell carcinoma: A retrospective multicenter GETUG (Groupe d’Etude des Tumeurs Uro-Genitales) study
Published in Journal of clinical oncology (01-02-2024)“…391 Background: Among patients with renal cell carcinoma (RCC), bone and visceral metastases have a poor prognosis, while endocrine gland metastases have a…”
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Atypical presentation of a central nervous system aspergillosis in a peripheral T cell lymphoma patient
Published in Annals of hematology (01-11-2020)Get full text
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Which place for avelumab in the management of urothelial carcinoma?
Published in Expert opinion on biological therapy (02-09-2019)“…: Urothelial carcinoma (UC) has a poor prognosis, with the only standard first-line metastatic treatment being platinum-based chemotherapy. Until 2018, there…”
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How Immunotherapy Has Redefined the Treatment Paradigm of Metastatic or Locally Advanced Muscle-Invasive Urothelial Bladder Carcinoma
Published in Cancers (01-05-2024)“…In the past decade, the therapeutic arsenal for metastatic bladder cancer has expanded considerably, with the development of immune checkpoint inhibitors…”
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Dramatic response after anti PD1 treatment failure in a squamous cell carcinoma of the maxillary sinus
Published in Oral oncology (01-12-2018)“…•Response with salvage chemotherapy was descript for head and neck carcinoma.•Few data concerning sinus cancer was noted.•We descripted a dramatic response…”
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Spatial transcriptomics of macrophage infiltration in non-small cell lung cancer reveals determinants of sensitivity and resistance to anti-PD1/PD-L1 antibodies
Published in Journal for immunotherapy of cancer (01-05-2022)“…Tumor-associated macrophages (TAMs) having immunosuppressive properties are one of the most abundant immune cells in the tumor microenvironment (TME)…”
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Therapeutic Management of Metastatic Clear Cell Renal Cell Carcinoma: A Revolution in Every Decade
Published in Cancers (17-12-2022)“…Clear cell renal cell carcinoma (RCC) oncogenesis is mainly driven by gene inactivation, leading to overexpression of vascular endothelial growth factor…”
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Resolution of immune checkpoint inhibitors-induced inflammatory arthritis while maintaining active treatment with checkpoint inhibitors and after its discontinuation: An observational study
Published in Joint, bone, spine : revue du rhumatisme (01-01-2025)“…•Immune checkpoint inhibitors can safely be continued in most patients developing immune checkpoint inhibitors-induced inflammatory arthritis.•Immune…”
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KS01.6.A UCPVAX-GLIO: A PHASE II TRIAL EVALUATING THE IMMUNOGENICITY AND EFFICACY OF AN ANTI-TELOMERASE VACCINE IN PATIENTS WITH NEWLY DIAGNOSED GBM
Published in Neuro-oncology (Charlottesville, Va.) (08-09-2023)“…Abstract BACKGROUND The Telomerase Reverse Transcriptase (TERT) is activated in 85%-90% of cancers, and glioblastomas (GBM) harbor the highest incidence of…”
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Clinical and Biological Differences between Upper Tract Carcinoma and Bladder Urothelial Cancer, Including Implications for Clinical Practice
Published in Cancers (23-11-2023)“…Upper tract urothelial carcinoma (UTUC) is a rare disease included, along with the much more frequent urothelial bladder cancer (BUC), in the family of…”
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Combinations of Anti-Angiogenic Agents and Immune Checkpoint Inhibitors in Renal Cell Carcinoma: Best Option?
Published in Cancers (07-02-2023)“…Over the past decade, major advances have been made in the treatment of advanced and metastatic renal cell carcinomas, specifically clear cell carcinomas. For…”
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Atypical presentation of a central nervous system aspergillosis in a peripheral T cell lymphoma patient
Published in Annals of hematology (01-11-2020)Get full text
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