Search Results - "Larrayoz, M"

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia by Boultwood, J, Perry, J, Pellagatti, A, Fernandez-Mercado, M, Fernandez-Santamaria, C, Calasanz, M J, Larrayoz, M J, Garcia-Delgado, M, Giagounidis, A, Malcovati, L, Della Porta, M G, Jädersten, M, Killick, S, Hellström-Lindberg, E, Cazzola, M, Wainscoat, J S

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Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration by Rodríguez, Ignacio R., Larrayoz, Ignacio M.

“…This review will discuss the formation and potential implications of 7-ketocholesterol (7KCh) in the retina. 7KCh is a proinflammatory oxysterol known to be…”
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Recurrent mutations refine prognosis in chronic lymphocytic leukemia by Baliakas, P, Hadzidimitriou, A, Sutton, L-A, Rossi, D, Minga, E, Villamor, N, Larrayoz, M, Kminkova, J, Agathangelidis, A, Davis, Z, Tausch, E, Stalika, E, Kantorova, B, Mansouri, L, Scarfò, L, Cortese, D, Navrkalova, V, Rose-Zerilli, M J J, Smedby, K E, Juliusson, G, Anagnostopoulos, A, Makris, A M, Navarro, A, Delgado, J, Oscier, D, Belessi, C, Stilgenbauer, S, Ghia, P, Pospisilova, S, Gaidano, G, Campo, E, Strefford, J C, Stamatopoulos, K, Rosenquist, R

“…Through the European Research Initiative on chronic lymphocytic leukemia (CLL) (ERIC), we screened 3490 patients with CLL for mutations within the NOTCH1 ( n…”
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Continuous production of biodiesel using supercritical fluids: A comparative study between methanol and ethanol by Santana, Aline, Maçaira, José, Larrayoz, M. Angeles

“…Biodiesel was produced from vegetable oil (triglycerides) by transesterification with supercritical ethanol and carbon dioxide as cosolvent in the presence of…”
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The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia by Rio-Machin, A, Gómez-López, G, Muñoz, J, Garcia-Martinez, F, Maiques-Diaz, A, Alvarez, S, Salgado, R N, Shrestha, M, Torres-Ruiz, R, Haferlach, C, Larráyoz, M J, Calasanz, M J, Fitzgibbon, J, Cigudosa, J C

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Targeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progression by Pellagatti, A, Roy, S, Di Genua, C, Burns, A, McGraw, K, Valletta, S, Larrayoz, M J, Fernandez-Mercado, M, Mason, J, Killick, S, Mecucci, C, Calasanz, M J, List, A, Schuh, A, Boultwood, J

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The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1 by Larrayoz, M, Blakemore, S J, Dobson, R C, Blunt, M D, Rose-Zerilli, M J J, Walewska, R, Duncombe, A, Oscier, D, Koide, K, Forconi, F, Packham, G, Yoshida, M, Cragg, M S, Strefford, J C, Steele, A J

“…The pro-survival Bcl-2 family member Mcl-1 is expressed in chronic lymphocytic leukaemia (CLL), with high expression correlated with progressive disease. The…”
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Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm by Menezes, J, Acquadro, F, Wiseman, M, Gómez-López, G, Salgado, R N, Talavera-Casañas, J G, Buño, I, Cervera, J V, Montes-Moreno, S, Hernández-Rivas, J M, Ayala, R, Calasanz, M J, Larrayoz, M J, Brichs, L F, Gonzalez-Vicent, M, Pisano, D G, Piris, M A, Álvarez, S, Cigudosa, J C

“…Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a very rare disease that currently lacks genomic and genetic biomarkers to assist in its clinical…”
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MicroRNA-guided drug discovery for mitigating persistent pulmonary complications in critical COVID-19 survivors: A longitudinal pilot study by García-Hidalgo, María C, Benítez, Iván D, Perez-Pons, Manel, Molinero, Marta, Belmonte, Thalía, Rodríguez-Muñoz, Carlos, Aguilà, María, Santisteve, Sally, Torres, Gerard, Moncusí-Moix, Anna, Gort-Paniello, Clara, Peláez, Rafael, Larráyoz, Ignacio M, Caballero, Jesús, Barberà, Carme, Nova-Lamperti, Estefania, Torres, Antoni, González, Jessica, Barbé, Ferran, de Gonzalo-Calvo, David

“…The post-acute sequelae of SARS-CoV-2 infection pose a significant global challenge, with nearly 50% of critical COVID-19 survivors manifesting persistent lung…”
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β3 integrin expression is required for invadopodia-mediated ECM degradation in lung carcinoma cells by Peláez, Rafael, Morales, Xabier, Salvo, Elizabeth, Garasa, Saray, Ortiz de Solórzano, Carlos, Martínez, Alfredo, Larrayoz, Ignacio M, Rouzaut, Ana

“…Cancer related deaths are primarily due to tumor metastasis. To facilitate their dissemination to distant sites, cancer cells develop invadopodia, actin-rich…”
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Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia by Parker, H, Rose-Zerilli, M J J, Larrayoz, M, Clifford, R, Edelmann, J, Blakemore, S, Gibson, J, Wang, J, Ljungström, V, Wojdacz, T K, Chaplin, T, Roghanian, A, Davis, Z, Parker, A, Tausch, E, Ntoufa, S, Ramos, S, Robbe, P, Alsolami, R, Steele, A J, Packham, G, Rodríguez-Vicente, A E, Brown, L, McNicholl, F, Forconi, F, Pettitt, A, Hillmen, P, Dyer, M, Cragg, M S, Chelala, C, Oakes, C C, Rosenquist, R, Stamatopoulos, K, Stilgenbauer, S, Knight, S, Schuh, A, Oscier, D G, Strefford, J C

“…Histone methyltransferases (HMTs) are important epigenetic regulators of gene transcription and are disrupted at the genomic level in a spectrum of human…”
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Influence of the turbulence model in CFD modeling of wall-to-fluid heat transfer in packed beds by Guardo, A., Coussirat, M., Larrayoz, M.A., Recasens, F., Egusquiza, E.

“…Computational fluid dynamics as a simulation tool allows obtaining a more detailed view of the fluid flow and heat transfer mechanisms in fixed-bed reactors,…”
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Cold Shock Proteins Are Expressed in the Retina Following Exposure to Low Temperatures by Larrayoz, Ignacio M, Rey-Funes, Manuel, Contartese, Daniela S, Rolón, Federico, Sarotto, Anibal, Dorfman, Veronica B, Loidl, Cesar F, Martínez, Alfredo

“…Hypothermia has been proposed as a therapeutic intervention for some retinal conditions, including ischemic insults. Cold exposure elevates expression of…”
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Adenosine A1 receptor: A neuroprotective target in light induced retinal degeneration by Soliño, Manuel, López, Ester María, Rey-Funes, Manuel, Loidl, César Fabián, Larrayoz, Ignacio M, Martínez, Alfredo, Girardi, Elena, López-Costa, Juan José

“…Light induced retinal degeneration (LIRD) is a useful model that resembles human retinal degenerative diseases. The modulation of adenosine A1 receptor is…”
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Comparative Analysis of Healthy and Cam-Type Femoroacetabular Impingement (FAI) Human Hip Joints Using the Finite Element Method by Lostado Lorza, Rubén, Somovilla Gomez, Fátima, Corral Bobadilla, Marina, Íñiguez Macedo, Saúl, Rodríguez San Miguel, Asier, Fernández Martínez, Enrique, Rubio Sampedro, Manuel, Pérez Sala, Álvaro, Cristóbal, Rafael Peláez, Larráyoz, Ignacio M.

“…In this study, a human hip joint with Cam-type Femoroacetabular Impingement (FAI) is studied by the Finite Element Method (FEM). This pathology consists of a…”
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CFD study on particle-to-fluid heat transfer in fixed bed reactors: Convective heat transfer at low and high pressure by Guardo, A., Coussirat, M., Recasens, F., Larrayoz, M.A., Escaler, X.

“…Computational fluid dynamics (CFD) has proven to be a reliable tool for fixed bed reactor design, through the resolution of 3D transport equations for mass,…”
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Non-coding NOTCH1 mutations in chronic lymphocytic leukemia; their clinical impact in the UK CLL4 trial by Larrayoz, M, Rose-Zerilli, M J J, Kadalayil, L, Parker, H, Blakemore, S, Forster, J, Davis, Z, Steele, A J, Collins, A, Else, M, Catovsky, D, Oscier, D G, Strefford, J C

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Hypothermia Prevents Retinal Damage Generated by Optic Nerve Trauma in the Rat by Rey-Funes, Manuel, Larrayoz, Ignacio M., Contartese, Daniela S., Soliño, Manuel, Sarotto, Anibal, Bustelo, Martín, Bruno, Martín, Dorfman, Verónica B., Loidl, César F., Martínez, Alfredo

“…Ocular and periocular traumatisms may result in loss of vision. Hypothermia provides a beneficial intervention for brain and heart conditions and, here, we…”
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Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration by Soliño, Manuel, Larrayoz, Ignacio M, López, Ester María, Rey-Funes, Manuel, Bareiro, Mariana, Loidl, Cesar Fabián, Girardi, Elena, Martínez, Alfredo, López-Costa, Juan José

“…Continuous illumination induces the degeneration of photoreceptors. This animal model of light-induced retinal degeneration resembles many characteristics of…”
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A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death and electroretinogram distortion in a rat model of intraorbital optic nerve crush (IONC) by Contartese, Daniela S, Rey-Funes, Manuel, Peláez, Rafael, Soliño, Manuel, Fernández, Juan C, Nakamura, Ronan, Ciranna, Nicolás S, Sarotto, Aníbal, Dorfman, Verónica B, López-Costa, Juan J, Zapico, José M, Ramos, Ana, de Pascual-Teresa, Beatriz, Larrayoz, Ignacio M, Loidl, César F, Martínez, Alfredo

“…Ocular and periocular traumatisms may result in loss of vision. Our previous work showed that therapeutic hypothermia prevents retinal damage caused by…”
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