Search Results - "Laroui, Nabila"

mRNA, a Revolution in Biomedicine by Baptista, Bruno, Carapito, Rita, Laroui, Nabila, Pichon, Chantal, Sousa, Fani

“…The perspective of using messenger RNA (mRNA) as a therapeutic molecule first faced some uncertainties due to concerns about its instability and the…”
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Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes by Laroui, Nabila, Coste, Maëva, Lichon, Laure, Bessin, Yannick, Gary-Bobo, Magali, Pratviel, Geneviève, Bonduelle, Colin, Bettache, Nadir, Ulrich, Sébastien

“…[Display omitted] In this work, we implemented a supramolecular approach in order to combine photodynamic therapy (PDT) with gene therapy. We made use of a…”
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Hydrocarbon-Stapled Peptide Based-Nanoparticles for siRNA Delivery by Simon, Matthieu, Laroui, Nabila, Heyraud, Marianne, Laconde, Guillaume, Ali, Lamiaa M A, Bourbiaux, Kevin, Subra, Gilles, Vezenkov, Lubomir L, Legrand, Baptiste, Amblard, Muriel, Bettache, Nadir

“…Small interfering RNAs (siRNAs) are promising molecules for developing new therapies based on gene silencing; however, their delivery into cells remains an…”
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Impact of net charge, targeting ligand amount and mRNA modification on the uptake, intracellular routing and the transfection efficiency of mRNA lipopolyplexes in dendritic cells by Delehedde, Christophe, Ciganek, Ivan, Rameix, Nathalie, Laroui, Nabila, Gonçalves, Cristine, Even, Luc, Midoux, Patrick, Pichon, Chantal

“…Targeting mRNA formulations to achieve cell specificity is one of the challenges that must be tackled to mettle their therapeutic potential. Here,…”
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Reverse poly(ε-caprolactone)-g-dextran graft copolymers. Nano-carriers for intracellular uptake of anticancer drugs by Delorme, Victor, Lichon, Laure, Mahindad, Hana, Hunger, Sylvie, Laroui, Nabila, Daurat, Morgane, Godefroy, Anastasia, Coudane, Jean, Gary-Bobo, Magali, Van Den Berghe, Hélène

“…[Display omitted] •Synthesis of a reverse oligosaccharide-based poly(ε-caprolactone)-g-dextran copolymer.•Preparation of cytocompatible and biodegradable…”
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La technologie de l’ARN messager by LAROUI, Nabila, PICHON, Chantal

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Improvement of Cell Penetrating Peptide for Efficient siRNA Targeting of Tumor Xenografts in Zebrafish Embryos by Laroui, Nabila, Cubedo, Nicolas, Rossel, Mireille, Bettache, Nadir

“…Cell‐penetrating peptides (CPPs) are one of the most efficient vectors for achieving cellular uptake of different cargos. However, their application in cancer…”
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Cell‐Selective siRNA Delivery Using Glycosylated Dynamic Covalent Polymers Self‐Assembled In Situ by RNA Templating by Laroui, Nabila, Coste, Maëva, Su, Dandan, Ali, Lamiaa M. A., Bessin, Yannick, Barboiu, Mihail, Gary‐Bobo, Magali, Bettache, Nadir, Ulrich, Sébastien

“…Dynamic covalent libraries enable exploring complex chemical systems from which bioactive assemblies can adaptively emerge through template effects. In this…”
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Structure‐Activity Relationships in Nucleic‐Acid‐Templated Vectors Based on Peptidic Dynamic Covalent Polymers by Su, Dan‐Dan, Ali, Lamiaa M. A., Coste, Maëva, Laroui, Nabila, Bessin, Yannick, Barboiu, Mihail, Bettache, Nadir, Ulrich, Sébastien

“…The use of nucleic acids as templates, which can trigger the self‐assembly of their own vectors represent an emerging, simple and versatile, approach toward…”
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Messenger RNA Lipid-Based Nanoparticles: Optimization of Formulations in the Lab by Delehedde, Christophe, Ciganek, Ivan, Laroui, Nabila, Rameix, Nathalie, Perche, Federico, Pichon, Chantal

“…Among the large variety of messenger RNA (mRNA) delivery systems, those developed with lipid-based formulations were the most widely used and efficient. In our…”
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Improvement of Cell Penetrating Peptide for Efficient siRNA Targeting of Tumor Xenografts in Zebrafish Embryos by Laroui, Nabila, Cubedo, Nicolas, Rossel, Mireille, Bettache, Nadir

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Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA by Delehedde, Christophe, Ciganek, Ivan, Bernard, Pierre Louis, Laroui, Nabila, Da Silva, Cathy Costa, Gonçalves, Cristine, Nunes, Jacques, Bennaceur-Griscelli, Anne-Lise, Imeri, Jusuf, Huyghe, Matthias, Even, Luc, Midoux, Patrick, Rameix, Nathalie, Guittard, Geoffrey, Pichon, Chantal

“…mRNA applications have undergone unprecedented applications—from vaccination to cell therapy. Natural killer (NK) cells are recognized to have a significant…”
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Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA by Delehedde, Christophe, Ciganek, Ivan, Bernard, Pierre Louis, Laroui, Nabila, da Silva, Cathy Costa, Gonçalves, Cristine, Nunes, Jacques, Bennaceur-Griscelli, Anne-Lise, Imeri, Jusuf, Huyghe, Matthias, Even, Luc, Midoux, Patrick, Rameix, Nathalie, Guittard, Geoffrey, Pichon, Chantal

“…mRNA applications have undergone unprecedented applications—from vaccination to cell therapy. Natural killer (NK) cells are recognized to have a significant…”
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Cell‐Selective siRNA Delivery Using Glycosylated Dynamic Covalent Polymers Self‐Assembled In Situ by RNA Templating by Laroui, Nabila, Coste, Maëva, Su, Dandan, Ali, Lamiaa M. A., Bessin, Yannick, Barboiu, Mihail, Gary‐Bobo, Magali, Bettache, Nadir, Ulrich, Sébastien

“…Dynamic covalent libraries enable exploring complex chemical systems from which bioactive assemblies can adaptively emerge through template effects. In this…”
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