Search Results - "Larocque, Nicholas"
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Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation
Published in Molecular cell (18-01-2008)“…FAK is known as an integrin- and growth factor-associated tyrosine kinase promoting cell motility. Here we show that, during mouse development, FAK…”
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2
Using a Multi-Stage hESC Model to Characterize BDE-47 Toxicity During Neurogenesis
Published in Toxicological sciences (01-09-2019)“…Although the ramifications associated with polybrominated diphenyl ethers (PBDEs) exposures during human pregnancy have yet to be determined, increasing…”
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Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification
Published in Development (Cambridge) (01-12-2015)“…Mechanisms of initial cell fate decisions differ among species. To gain insights into lineage allocation in humans, we derived ten human embryonic stem cell…”
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Establishment of Human Trophoblast Progenitor Cell Lines from the Chorion
Published in Stem cells (Dayton, Ohio) (01-09-2011)“…Placental trophoblasts are key determinants of in utero development. Mouse trophoblast (TB) stem cells, which were first derived over a decade ago, are a…”
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Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta
Published in Journal of virology (01-05-2015)“…Human cytomegalovirus (HCMV) is a major cause of birth defects that include severe neurological deficits, hearing and vision loss, and intrauterine growth…”
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An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells
Published in Environmental health perspectives (31-10-2017)“…Observational studies have reported associations between maternal phthalate levels and adverse outcomes at birth and in the health of the child. Effects on…”
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The role of chorionic cytotrophoblasts in the smooth chorion fusion with parietal decidua
Published in Placenta (Eastbourne) (01-07-2015)“…Abstract Background/purpose Human placenta and chorion are rapidly growing transient embryonic organs built from diverse cell populations that are of either,…”
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Human embryonic stem cells as a model system for studying the effects of smoke exposure on the embryo
Published in Reproductive toxicology (Elmsford, N.Y.) (01-10-2008)“…Human embryonic stem cells (hESCs) share many characteristics including pluripotency with cells of the early embryo and so are potentially useful tools for…”
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Focal Adhesion Kinase Controls pH-Dependent Epidermal Barrier Homeostasis by Regulating Actin-Directed Na+ /H+ Exchanger 1 Plasma Membrane Localization
Published in The American journal of pathology (01-06-2007)“…Ubiquitously expressed focal adhesion kinase (FAK), linked to multiple intracellular signaling pathways, has previously been shown to control cell motility,…”
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