Search Results - "Laroche, Julian"

PK-PD Evaluation of Inhaled Microparticles loaded with Ciprofloxacin-Copper complex in a Rat Model of Chronic Pseudomonas aeruginosa Lung Infection by Tewes, Frederic, Lamy, Barbara, Laroche, Julian, Lamarche, Isabelle, Marchand, Sandrine

“…The potential gain in efficacy of pulmonary administration over IV administration of some antibiotics such as ciprofloxacin (CIP) may be limited by the short…”
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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 5. Oseltamivir Carboxylate by Galindo Bedor, Danilo Cesar, Marchand, Sandrine, Lamarche, Isabelle, Laroche, Julian, Pereira de Santana, Davi, Couet, William

“…The aim of this study was to determine the biopharmaceutical characteristics of oseltamivir carboxylate (OC) after pulmonary delivery. After OC bolus and…”
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Colistin-loaded aerosolizable particles for the treatment of bacterial respiratory infections by Landa, Guillermo, Alejo, Teresa, Sauzet, Theo, Laroche, Julian, Sebastian, Victor, Tewes, Frederic, Arruebo, Manuel

“…[Display omitted] Compared to parenteral administration of colistin, its direct pulmonary administration can maximize lung drug deposition while reducing…”
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Pulmonary Pharmacokinetics of Oseltamivir Carboxylate in Rats after Nebulization or Intravenous Administration of Its Prodrug, Oseltamivir Phosphate by Carrez, Romain, Brillault, Julien, Grégoire, Nicolas, Lamarche, Isabelle, Laroche, Julian, Couet, William, Marchand, Sandrine

“…The aim of this study was to investigate the pharmacokinetics of oseltamivir phosphate, a prodrug, and its active moiety in plasma and lung after its…”
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A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion by Viel, Alexis, Henri, Jérôme, Bouchène, Salim, Laroche, Julian, Rolland, Jean-Guy, Manceau, Jacqueline, Laurentie, Michel, Couet, William, Grégoire, Nicolas

“…Purpose The objective was the development of a whole-body physiologically-based pharmacokinetic (WB-PBPK) model for colistin, and its prodrug colistimethate…”
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Lack of experimental evidence to support mcr-1-positive Escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets by Viel, Alexis, Henri, Jérôme, Perrin-Guyomard, Agnès, Laroche, Julian, Couet, William, Grégoire, Nicolas, Laurentie, Michel

“…•Piglets harbouring mcr-1-positive Escherichia coli were treated orally with colistin.•Recommended European dosage and double dosage of colistin were given by…”
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