Search Results - "Larmonier, N."

Modulation of neutrophil motility by curcumin: Implications for inflammatory bowel disease by Larmonier, C.B., Midura‐Kiela, M.T., Ramalingam, R., Laubitz, D., Janikashvili, N., Larmonier, N., Ghishan, F.K., Kiela, P.R.

“…Background: Neutrophils (PMN) are the first cells recruited at the site of inflammation. They play a key role in the innate immune response by recognizing,…”
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An immunological signature to predict outcome in patients with triple-negative breast cancer with residual disease after neoadjuvant chemotherapy by Blaye, C., Darbo, É., Debled, M., Brouste, V., Vélasco, V., Pinard, C., Larmonier, N., Pellegrin, I., Tarricone, A., Arnedos, M., Commeny, J., Bonnefoi, H., Larmonier, C., MacGrogan, G.

“…When triple-negative breast cancer (TNBC) patients have residual disease after neoadjuvant chemotherapy (NACT), they have a high risk of metastatic relapse…”
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Increase of CD4⁺CD25⁺ regulatory T cells in the peripheral blood of patients with metastatic carcinoma: a Phase I clinical trial using cyclophosphamide and immunotherapy to eliminate CD4⁺CD25⁺ T lymphocytes by Audia, S, Nicolas, A, Cathelin, D, Larmonier, N, Ferrand, C, Foucher, P, Fanton, A, Bergoin, E, Maynadie, M, Arnould, L, Bateman, A, Lorcerie, B, Solary, E, Chauffert, B, Bonnotte, B

“…We determined the number and functional status of CD4⁺CD25high regulatory T cells (Treg) in blood samples from patients with metastatic carcinoma, and…”
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Human ovarian tumour-derived chaperone-rich cell lysate (CRCL) elicits T cell responses in vitro by Li, G, Zeng, Y, Chen, X, Larmonier, N, Sepassi, M, Graner, M.W, Andreansky, S, Brewer, M.A, Katsanis, E

“…Tumour-derived chaperone-rich cell lysate (CRCL), which is made up of numerous heat shock proteins, has been used successfully to generate tumour-specific T…”
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Identification of Tumor-Infiltrating Macrophages as the Killers of Tumor Cells After Immunization in a Rat Model System by Bonnotte, Bernard, Larmonier, Nicolas, Favre, Nathalie, Fromentin, Annie, Moutet, Monique, Martin, Monique, Gurbuxani, Sandeep, Solary, Eric, Chauffert, Bruno, Martin, Francois

“…Immunization can prevent tumor growth, but the effector cells directly responsible for tumor cell killing in immunized hosts remain undetermined. The present…”
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CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative by Ghiringhelli, François, Larmonier, Nicolas, Schmitt, Elise, Parcellier, Arnaud, Cathelin, Dominique, Garrido, Carmen, Chauffert, Bruno, Solary, Eric, Bonnotte, Bernard, Martin, François

“…We investigated the mechanisms of immune tolerance raised by tumors by comparing immunogenic and tolerogenic tumor cell clones isolated from a rat colon…”
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Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis by Samson, Maxime, Audia, Sylvain, Fraszczak, Jennifer, Trad, Malika, Ornetti, Paul, Lakomy, Daniela, Ciudad, Marion, Leguy, Vanessa, Berthier, Sabine, Vinit, Julien, Manckoundia, Patrick, Maillefert, Jean-Francis, Besancenot, Jean-François, Aho-Glele, Serge, Olsson, Nils Olivier, Lorcerie, Bernard, Guillevin, Loïc, Mouthon, Luc, Saas, Philippe, Bateman, Andrew, Martin, Laurent, Janikashvili, Nona, Larmonier, Nicolas, Bonnotte, Bernard

“…Objective Giant cell arteritis (GCA) is the most frequently occurring vasculitis in elderly individuals, and its pathogenesis is not fully understood. The…”
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Dendritic cell tumor killing activity and its potential applications in cancer immunotherapy by Hanke, Neale, Alizadeh, Darya, Katsanis, Emmanuel, Larmonier, Nicolas

“…Universally viewed as the sentinels and messengers of the immune system and traditionally referred to as professional antigen-presenting cells, dendritic cells…”
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MIP-3α Transfection into a Rodent Tumor Cell Line Increases Intratumoral Dendritic Cell Infiltration but Enhances (Facilitates) Tumor Growth and Decreases Immunogenicity by Bonnotte, Bernard, Crittenden, Marka, Larmonier, Nicolas, Gough, Michael, Vile, Richard G.

“…Abstract Dendritic cells are powerful APCs for activation of specific antitumor T lymphocytes. To present tumor Ags efficiently, they have first to migrate to…”
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Chaperone-rich tumor cell lysate-mediated activation of antigen-presenting cells resists regulatory T cell suppression by Larmonier, Nicolas, Cantrell, Jessica, LaCasse, Collin, Li, Gang, Janikashvili, Nona, Situ, Elaine, Sepassi, Marjan, Andreansky, Samita, Katsanis, Emmanuel

“…CD4+CD25+ regulatory T lymphocytes (Tregs) critically contribute to the mechanisms of cancer‐induced tolerance. These cells suppress anti‐tumoral CD8+ and CD4+…”
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Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells by GURBUXANI, Sandeep, BRUEY, Jean-Marie, FROMENTIN, Annie, LARMONIER, Nicolas, PARCELLIER, Arnaud, JÄÄTTELÄ, Marja, MARTIN, Francois, SOLARY, Eric, GARRIDO, Carmen

“…Expression of inducible heat shock protein 70 (HSP70) in tumor cells has been proposed to enhance their immunogenicity. However, HSP70 has also been…”
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Polychlorinated Biphenyl-Induced Effects on Metabolic Enzymes, AP-1 Binding, Vitamin E, and Oxidative Stress in the Rat Liver by Twaroski, Timothy P., O'Brien, Michelle L., Larmonier, Nicolas, Glauert, Howard P., Robertson, Larry W.

“…Environmental pollutants, such as polychlorinated biphenyls (PCBs), may induce drug metabolism and may be substrates for the induced metabolic enzymes. Both…”
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CD4 super(+)CD25 super(+)FoxP3 super(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease by Chen, X, Zhou, B, Li, M, Deng, Q, Wu, X, Le, X, Wu, C, Larmonier, N, Zhang, W, Zhang, H, Wang, H, Katsanis, E

“…CD4 super(+)CD25 super(+) regulatory T cells (Treg) play a central role in the prevention of autoimmunity and in the control of immune responses by…”
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Increase of CD4 super(+)CD25 super(+) regulatory T cells in the peripheral blood of patients with metastatic carcinoma: a Phase I clinical trial using cyclophosphamide and immunotherapy to eliminate CD4 super(+)CD25 super(+) T lymphocytes by Audia, S, Nicolas, A, Cathelin, D, Larmonier, N, Ferrand, C, Foucher, P, Fanton, A, Bergoin, E, Maynadie, M, Arnould, L, Bateman, A, Lorcerie, B, Solary, E, Chauffert, B, Bonnotte, B

“…We determined the number and functional status of CD4 super(+)CD25 super(high) regulatory T cells (T sub(reg)) in blood samples from patients with metastatic…”
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Freshly isolated bone marrow cells induce death of various carcinoma cell lines by Larmonier, Nicolas, Ghiringhelli, François, Larmonier, Claire B., Moutet, Monique, Fromentin, Annie, Baulot, Emmanuel, Solary, Eric, Bonnotte, Bernard, Martin, François

“…In some carcinomas such as digestive tract carcinomas, bone marrow infiltration by tumor cells is a frequent event but usually remains a micrometastatic…”
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CD4 super(+)CD25 super(+) regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative by Ghiringhelli, F, Larmonier, N, Schmitt, E, Parcellier, A, Cathelin, D, Garrido, C, Chauffert, B, Solary, E, Bonnotte, B, Martin, F

“…We investigated the mechanisms of immune tolerance raised by tumors by comparing immunogenic and tolerogenic tumor cell clones isolated from a rat colon…”
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Kinetics of tumor cell apoptosis and immune cell activation during the regression of tumors induced by lipid A in a rat model of colon cancer by Larmonier, Claire B, Arnould, Laurent, Larmonier, Nicolas, Baumann, Sylvie, Moutet, Monique, Saint-Giorgio, Valérie, Pance, Alena, Jeannin, Jean-François

“…Despite the wide range of available therapies, human colon cancers remain difficult to cure. Evidence for efficient antitumoral immune responses to be raised…”
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An atypical caspase-independent death pathway for an immunogenic cancer cell line by LARMONIER, Nicolas, BILLEREY, Claire, BONNOTTE, Bernard, REBE, Cédric, PARCELLIER, Arnaud, MOUTET, Monique, FROMENTIN, Annie, KROEMER, Guido, GARRIDO, Carmen, SOLARY, Eric, MARTIN, Francois

“…REGb cell line, a highly immunogenic tumor cell variant isolated from a rat colon cancer, yields regressive tumors when injected into syngeneic hosts. We…”
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Peritransplantation Vaccination with Chaperone-Rich Cell Lysate Induces Antileukemia Immunity by Chen, Xinchun, Zeng, Yi, Li, Gang, Larmonier, Nicolas, Graner, Michael W., Katsanis, Emmanuel

“…We have reported that chaperone-rich cell lysate (CRCL) is an effective anticancer vaccine in immunocompetent mice. In this study, we explored the therapeutic…”
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