Search Results - "Larman, MG"

Maintenance of the meiotic spindle during vitrification in human and mouse oocytes by Larman, MG, Minasi, MG, Rienzi, L, Gardner, DK

“…Abstract Vitrification appears to be a viable method for the cryopreservation of human metaphase II (MII) oocytes, but concerns regarding the concentration of…”
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PLC zeta: a sperm-specific trigger of Ca(2+) oscillations in eggs and embryo development by Saunders, Christopher M, Larman, Mark G, Parrington, John, Cox, Llewellyn J, Royse, Jillian, Blayney, Lynda M, Swann, Karl, Lai, F Anthony

“…Upon fertilisation by sperm, mammalian eggs are activated by a series of intracellular Ca(2+) oscillations that are essential for embryo development. The…”
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Calcium-free vitrification reduces cryoprotectant-induced zona pellucida hardening and increases fertilization rates in mouse oocytes by Larman, Mark G, Sheehan, Courtney B, Gardner, David K

“…Despite the success of embryo cyropreservation, routine oocyte freezing has proved elusive with only around 200 children born since the first reported birth in…”
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Cell cycle-dependent Ca2+ oscillations in mouse embryos are regulated by nuclear targeting of PLCζ by Larman, Mark G., Saunders, Christopher M., Carroll, John, Lai, F. Anthony, Swann, Karl

“…During the first cell cycle Ca2+ oscillations are regulated in a cell cycle-dependent manner, such that the oscillations are unique to M phase. How the Ca2+…”
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Role of Phospholipase C-ζ Domains in Ca2+-dependent Phosphatidylinositol 4,5-Bisphosphate Hydrolysis and Cytoplasmic Ca2+ Oscillations by Nomikos, Michail, Blayney, Lynda M., Larman, Mark G., Campbell, Karen, Rossbach, Andreas, Saunders, Christopher M., Swann, Karl, Lai, F. Anthony

“…The sperm-specific phospholipase C-ζ (PLCζ) elicits fertilization-like Ca2+ oscillations and activation of embryo development when microinjected into mammalian…”
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The cytosolic sperm factor that triggers Ca2+ oscillations and egg activation in mammals is a novel phospholipase C: PLCζ by Swann, K, Larman, M G, Saunders, C M, Lai, F A

“…When sperm activate eggs at fertilization the signal for activation involves increases in the intracellular free Ca2+ concentration. In mammals the Ca2+…”
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Sperm phospholipase Czeta from humans and cynomolgus monkeys triggers Ca2+ oscillations, activation and development of mouse oocytes by Cox, LJ, Larman, MG, Saunders, CM, Hashimoto, K, Swann, K, Lai, FA

“…Fusion with a fertilizing spermatozoon induces the mammalian oocyte to undergo a remarkable series of oscillations in cytosolic Ca(2+), leading to oocyte…”
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Calcium and mitosis by Whitaker, Michael, Larman, Mark G.

“…Calcium is thought to be involved in regulating mitotic transitions. The basis for this view is set out. Recent data from experiments on sea urchin embryos is…”
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Vitrification of mouse pronuclear oocytes with no direct liquid nitrogen contact by Larman, Mark G, Sheehan, Courtney B, Gardner, David K

“…The ability to routinely cryopreserve human oocytes and embryos represents a significant advancement in the field of assisted reproductive technology. Although…”
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The role of calcium in ABA‐induced gene expression and stomatal movements by Webb, Alex A. R., Larman, Mark G., Montgomery, Lucy T., Taylor, Jane E., Hetherington, Alistair M.

“…Summary There is much interest in the transduction pathways by which abscisic acid (ABA) regulates stomatal movements (ABA‐turgor signalling) and by which this…”
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Inhibiting MAP Kinase Activity Prevents Calcium Transients and Mitosis Entry in Early Sea Urchin Embryos by Philipova, Rada, Larman, Mark G., Leckie, Calum P., Harrison, Patrick K., Groigno, Laurence, Whitaker, Michael

“…A transient calcium increase triggers nuclear envelope breakdown (mitosis entry) in sea urchin embryos. Cdk1/cyclin B kinase activation is also known to be…”
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