Search Results - "Larkin, Sarah"
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Pathology and pathogenesis of craniopharyngiomas
Published in Pituitary (01-03-2013)“…Craniopharyngiomas are benign but locally invasive tumours of the sellar region that occur as two subtypes. The adamantinomatous type (aCP) occurs mainly…”
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Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations
Published in Cancer research (Chicago, Ill.) (01-01-2016)“…Mutations in the isocitrate dehydrogenase genes (IDH1/2) occur often in diffuse gliomas, where they are associated with abnormal accumulation of the…”
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Recent advances in molecular pathology of craniopharyngioma [version 1; peer review: 2 approved]
Published in F1000 research (2017)“…Craniopharyngiomas are rare epithelial tumours arising along the path of the craniopharyngeal duct. Two major histological subtypes have been recognised, the…”
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Review of enhanced recovery programs in benign gynecologic surgery
Published in International Urogynecology Journal (2018)“…Introduction and hypothesis Enhanced recovery programs (ERPs) are evidence-based protocols designed to improve functional rehabilitation after surgery. ERPs…”
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Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance
Published in Nucleic acids research (01-09-2010)“…Glyoxal and methylglyoxal are reactive dicarbonyl metabolites formed and metabolized in physiological systems. Increased exposure to these dicarbonyls is…”
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Oncolytic herpesvirus expressing PD-L1 BiTE for cancer therapy: exploiting tumor immune suppression as an opportunity for targeted immunotherapy
Published in Journal for immunotherapy of cancer (05-04-2021)“…BackgroundProgrammed death-ligand 1 (PD-L1) is an important immune checkpoint protein that can be regarded as a pan-cancer antigen expressed by multiple…”
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A comparison of 2‐hydroxyglutarate detection at 3 and 7 T with long‐TE semi‐LASER
Published in NMR in biomedicine (01-03-2018)“…Abnormally high levels of the ‘oncometabolite’ 2‐hydroxyglutarate (2‐HG) occur in many grade II and III gliomas, and correlate with mutations in the genes of…”
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A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR Spectroscopy
Published in Metabolites (20-02-2019)“…The oncogenes that are expressed in gliomas reprogram particular pathways of glucose, amino acids, and fatty acid metabolism. Mutations in isocitrate…”
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Prevalence of positive screening test for cognitive impairment among elderly urogynecologic patients
Published in American journal of obstetrics and gynecology (01-11-2016)“…Background Impaired cognition has been correlated with adverse postoperative outcomes, such as an increased incidence of delirium, a longer length of hospital…”
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The Wnt Signalling Cascade and the Adherens Junction Complex in Craniopharyngioma Tumorigenesis
Published in Endocrine pathology (01-03-2015)“…Craniopharyngiomas are epithelial, sellar tumours with adamantinomatous (aCP) and papillary (pCP) subtypes. The aCP type usually occurs during childhood and…”
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Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro
Published in Annals of the New York Academy of Sciences (01-04-2008)“…Dicarbonyl glycation of RGD and GFOGER sites in type IV collagen has been associated with decreased angiogenesis. In this study, we investigated whether…”
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Effects of hydroxyethyl starch 6 % (130/0.4) on blood loss during cesarean delivery: a propensity-matched analysis
Published in Journal of anesthesia (01-10-2016)“…Background Hydroxyethyl starch is commonly used in the obstetric patient population to prevent hypotension during cesarean delivery. Evidence suggests…”
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Sequence analysis of the catalytic subunit of PKA in somatotroph adenomas
Published in European journal of endocrinology (01-12-2014)“…ObjectiveThe pathogenetic mechanisms of sporadic somatotroph adenomas are not well understood, but derangements of the cAMP pathway have been implicated…”
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Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study
Published in Acta neuropathologica communications (01-06-2016)“…Non-syndromic pituitary gigantism can result from AIP mutations or the recently identified Xq26.3 microduplication causing X-linked acrogigantism (XLAG)…”
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Regulation of the Third Member of the Uncoupling Protein Family, UCP3, by Cold and Thyroid Hormone
Published in Biochemical and biophysical research communications (07-11-1997)“…Uncoupling protein (UCP1) is a transmembrane proton transporter present in the mitochondria of brown adipose tissue (BAT), a specialized tissue which functions…”
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Thermal transport barrier in carbon nanotube array nano-thermal interface materials
Published in Carbon (New York) (01-08-2017)“…Although carbon nanotubes (CNTs) could theoretically achieve thermal conductivity (kCNT) as high as 100 W/m K, the nature of height non-uniformity could induce…”
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Verification of the Collapsed Cone algorithm using a 3D printed phantom with varying densities
Published in Physica medica (01-10-2017)“…The purpose of the study was to test the feasibility of using 3D printing technology to create an inhomogeneous phantom for the verification of the Collapsed…”
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Verification of the Collapsed Cone algorithm using a 3D printed phantom with varying densities
Published in Physica medica (01-10-2017)“…The purpose of the study was to test the feasibility of using 3D printing technology to create an inhomogeneous phantom for the verification of the Collapsed…”
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My Mother Weakens
Published in Christian journal for global health (31-05-2019)“…A poem on peace with the injustice of death…”
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What is the cry of your heart?: Collective reflections from 7th Triennial Micah Global Consultation
Published in Christian journal for global health (01-01-2019)Get full text
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