Search Results - "Larkin, Daniel F. P."

Corneal cross-linking versus standard care in children with keratoconus - a randomised, multicentre, observer-masked trial of efficacy and safety (KERALINK): a statistical analysis plan by Chowdhury, Kashfia, Doré, Caroline J, Bunce, Catey, Larkin, Daniel F P

“…The KERALINK trial tests the hypothesis that corneal cross-linking (CXL) treatment reduces the progression of keratoconus in comparison to standard care in…”
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High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis by Khwaja, Jahanzaib, Bomsztyk, Joshua, Mahmood, Shameem, Wisniowski, Brendan, Shah, Raakhee, Tailor, Anish, Yong, Kwee, Popat, Rakesh, Rabin, Neil, Kyriakou, Charalampia, Sive, Jonathan, Esposti, Simona Degli, Larkin, Daniel F. P., Worthington, Sarah, Hart, Alyse, Dowling, Emma, Correia, Nuno, Bygrave, Ceri, Rydzewski, Andrzej, Jamroziak, Krzysztof, Wechalekar, Ashutosh D.

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Quality of Vision and Graft Thickness in Deep Anterior Lamellar and Penetrating Corneal Allografts by Ardjomand, Navid, MD, Hau, Scott, OD, McAlister, James C., MD, Bunce, Catey, DSC, Galaretta, David, MD, Tuft, Stephen J., MD, Larkin, Daniel F.P., MD

“…Purpose To compare visual function after deep anterior lamellar keratoplasty (DALK) with visual function after penetrating keratoplasty (PK) for keratoconus…”
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Update on Herpes simplex keratitis management by Sibley, Daniel, Larkin, Daniel F. P.

“…Herpes simplex keratitis (HSK) is a common, potentially blinding condition characterised by recurrent infections of the cornea, seen by both general…”
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Inflammatory Cytokines Induce Apoptosis of Corneal Endothelium through Nitric Oxide by Sagoo, Pervinder, Chan, Giulia, Larkin, Daniel F. P, George, Andrew J. T

“…Proinflammatory cytokines are integral components of the allogeneic response to a corneal transplant and contribute to the pathogenesis of graft failure that…”
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Diagnosis and management of keratoconus in the paediatric age group: a review of current evidence by Price, Liam D., Larkin, Daniel F. P.

“…The diagnosis and management of keratoconus in the paediatric age group presents additional challenges to those encountered in adults. The most significant of…”
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Function of indoleamine 2,3‐dioxygenase in corneal allograft rejection and prolongation of allograft survival by over‐expression by Beutelspacher, Sven C., Pillai, Radhakrishna, Watson, Martin P., Tan, Peng H., Tsang, Julia, McClure, Myra O., George, Andrew J. T., Larkin, Daniel F. P.

“…Indoleamine 2,3‐dioxygenase (IDO) suppresses T cell responses by its action in catabolising tryptophan. It is important in maintenance of immune privilege in…”
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Graphical comparison of surgeon outcomes for the audit of a national corneal transplant registry (OTAG study 32) by Hopkinson, Cathy, Curnow, Elinor, Larkin, Daniel F. P., Prydal, Jeremy, Tuft, Stephen

“…Purpose To compare Kaplan–Meier survival curves and funnel plots for the audit of surgeon-specific corneal transplantation outcomes. Methods We obtained data…”
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New Pharmacological Approaches for the Treatment of Neurotrophic Keratitis by Koay, Su Yin, Larkin, Daniel F P

“…Neurotrophic keratitis (NK) is a rare degenerative condition that is caused by damage to the trigeminal nerve, with partial or complete loss of corneal sensory…”
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Surgical innovation in ophthalmology: challenges and opportunities by Azuara-Blanco, Augusto, Carlisle, Aaron, Jayaram, Hari, Gazzard, Gus, Larkin, Daniel F. P., Wickham, Louisa, Lois, Noemi, Bicket, Amanda

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Differential Effects of Costimulatory Pathway Modulation on Corneal Allograft Survival by Watson, Martin P, George, Andrew J. T, Larkin, Daniel F. P

“…T lymphocytes have a central role in allograft rejection. On engagement of the T cell receptor by antigenic peptide-major histocompatibility complex (MHC)…”
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Pulsed oral corticosteroids for the treatment of vernal and atopic keratoconjunctivitis: a management plan by Fernando, Pasan, Marziali, Elisa, Chlubek, Marta, Larkin, Daniel F P, Hingorani, Melanie, Tuft, Stephen, Dahlmann-Noor, Annegret

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Diagnostic accuracy of microbial keratitis with in vivo scanning laser confocal microscopy by Hau, Scott C, Dart, John K G, Vesaluoma, Minna, Parmar, Dipak N, Claerhout, Ilse, Bibi, Kanom, Larkin, Daniel F P

“…To determine the accuracy of diagnosing microbial keratitis by masked medical and non-medical observers using the Heidelberg Retina Tomograph II/Rostock Cornea…”
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Center and Surgeon Effect on Outcomes of Endothelial Keratoplasty versus Penetrating Keratoplasty in the United Kingdom by Greenrod, Edward B, Jones, Mark N.A, Kaye, Stephen, Larkin, Daniel F.P

“…Purpose To compare national outcomes of endothelial keratoplasty (EK) and penetrating keratoplasty (PK) during comparable 6-year periods. Design Prospective…”
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Identification of Therapeutic Targets of Inflammatory Monocyte Recruitment to Modulate the Allogeneic Injury to Donor Cornea by Lapp, Thabo, Zaher, Sarah S, Haas, Carolin T, Becker, David L, Thrasivoulou, Chris, Chain, Benjamin M, Larkin, Daniel F P, Noursadeghi, Mahdad

“…We sought to test the hypothesis that monocytes contribute to the immunopathogenesis of corneal allograft rejection and identify therapeutic targets to inhibit…”
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A randomised, controlled, observer-masked trial of corneal cross-linking for progressive keratoconus in children: the KERALINK protocol by Chowdhury, Kashfia, Dore, Caroline, Burr, Jennifer M, Bunce, Catey, Raynor, Mathew, Edwards, Matthew, Larkin, Daniel F P

“…IntroductionThe KERALINK trial tests the hypothesis that corneal cross-linking (CXL) treatment reduces the progression of keratoconus in comparison to standard…”
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Characteristics of endothelial corneal transplant rejection following immunisation with SARS-CoV-2 messenger RNA vaccine by Phylactou, Maria, Li, Ji-Peng Olivia, Larkin, Daniel F P

“…We report two cases of endothelial corneal allograft rejection following immunisation with SARS-CoV-2 messenger RNA (mRNA) vaccine BNT162b2 and describe the…”
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Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition by Khan, Adnan, Fu, Hongmei, Tan, Lee Aun, Harper, Jennifer E., Beutelspacher, Sven C., Larkin, Daniel F. P., Lombardi, Giovanna, McClure, Myra O., George, Andrew J. T.

“…Dendritic cell (DC) modification is a potential strategy to induce clinical transplantation tolerance. We compared two DC modification strategies to inhibit…”
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Corneal Transplant Surgery for Keratoconus and the Effect of Surgeon Experience on Deep Anterior Lamellar Keratoplasty Outcomes by Kasbekar, Shivani A, Jones, Mark N.A, Ahmad, Sajjad, Larkin, Daniel F.P, Kaye, Stephen B

“…Purpose To investigate graft survival and surgical experience on clinical outcome following deep anterior lamellar keratoplasty (DALK). Design Multicenter…”
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Effect of Glaucoma on Corneal Graft Survival According to Indication for Penetrating Keratoplasty by Stewart, Rosalind M.K, Jones, Mark N.A, Batterbury, Mark, Tole, Derek, Larkin, Daniel F.P, Kaye, Stephen B

“…Purpose To determine whether the risk of graft failure in patients with glaucoma is dependent on the indication for penetrating keratoplasty (PK). Design…”
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