Search Results - "Lariviere, Mathieu"

Allele-Specific Chromatin Remodeling in the ZPBP2/GSDMB/ORMDL3 Locus Associated with the Risk of Asthma and Autoimmune Disease by Verlaan, Dominique J., Berlivet, Soizik, Hunninghake, Gary M., Madore, Anne-Marie, Larivière, Mathieu, Moussette, Sanny, Grundberg, Elin, Kwan, Tony, Ouimet, Manon, Ge, Bing, Hoberman, Rose, Swiatek, Marcin, Dias, Joana, Lam, Kevin C.L., Koka, Vonda, Harmsen, Eef, Soto-Quiros, Manuel, Avila, Lydiana, Celedón, Juan C., Weiss, Scott T., Dewar, Ken, Sinnett, Daniel, Laprise, Catherine, Raby, Benjamin A., Pastinen, Tomi, Naumova, Anna K.

“…Common SNPs in the chromosome 17q12-q21 region alter the risk for asthma, type 1 diabetes, primary biliary cirrhosis, and Crohn disease. Previous reports by us…”
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Multisite verification of the accuracy of a multi-gene next generation sequencing panel for detection of mutations and copy number alterations in solid tumours by Bartlett, John, Amemiya, Yutaka, Arts, Heleen, Bayani, Jane, Eng, Barry, Grafodatskaya, Daria, Kamel Reid, Suzanne, Lariviere, Mathieu, Lo, Bryan, McClure, Rebecca, Mittal, Vinay, Sadikovic, Bekim, Sadis, Seth, Seth, Arun, Smith, Jeff, Zhang, Xiao, Feilotter, Harriet

“…Molecular variants including single nucleotide variants (SNVs), copy number variants (CNVs) and fusions can be detected in the clinical setting using deep…”
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Rare allelic forms of PRDM9 associated with childhood leukemogenesis by Hussin, Julie, Sinnett, Daniel, Casals, Ferran, Idaghdour, Youssef, Bruat, Vanessa, Saillour, Virginie, Healy, Jasmine, Grenier, Jean-Christophe, de Malliard, Thibault, Busche, Stephan, Spinella, Jean-François, Larivière, Mathieu, Gibson, Greg, Andersson, Anna, Holmfeldt, Linda, Ma, Jing, Wei, Lei, Zhang, Jinghui, Andelfinger, Gregor, Downing, James R, Mullighan, Charles G, Awadalla, Philip

“…One of the most rapidly evolving genes in humans, PRDM9, is a key determinant of the distribution of meiotic recombination events. Mutations in this…”
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Functional analysis of promoter variants in KU70 and their role in cancer susceptibility by Ouimet, Manon, Cassart, Pauline, Larivière, Mathieu, Kritikou, Ekaterini A., Simard, Jacques, Sinnett, Daniel

“…KU70 is involved in the DNA double‐strand break repair pathway, which plays a critical role in maintaining genomic stability and preventing cancer. Genetic…”
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ALG: automated genotype calling of Luminex assays by Bourgey, Mathieu, Lariviere, Mathieu, Richer, Chantal, Sinnett, Daniel

“…Single nucleotide polymorphisms (SNPs) are the most commonly used polymorphic markers in genetics studies. Among the different platforms for SNP genotyping,…”
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Identification of functional DNA variants in the constitutive promoter region of MDM2 by Lalonde, Marie-Eve, Ouimet, Manon, Larivière, Mathieu, Kritikou, Ekaterini A, Sinnett, Daniel

“…Although mutations in the oncoprotein murine double minute 2 (MDM2) are rare, MDM2 gene overexpression has been observed in several human tumors. Given that…”
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Functional impact of sequence variation in the promoter region of TGFB1 by Healy, Jasmine, Dionne, Joëlle, Bélanger, Hélène, Larivière, Mathieu, Beaulieu, Patrick, Labuda, Damian, Sinnett, Daniel

“…Pathological deregulation of the transforming growth factor, beta 1 (TGFB1) pathway has been implicated in the development of several major diseases, including…”
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Relationship between cholesteryl ester transfer protein and LDL heterogeneity in familial hypercholesterolemia by Hogue, Jean-Charles, Lamarche, Benoît, Gaudet, Daniel, Larivière, Mathieu, Tremblay, André J., Bergeron, Jean, Lemieux, Isabelle, Després, Jean-Pierre, Gagné, Claude, Couture, Patrick

“…Small, dense LDL particles have been associated with an increased risk of coronary artery disease, and cholesteryl ester transfer protein (CETP) has been…”
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Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans by Casals, Ferran, Hodgkinson, Alan, Hussin, Julie, Idaghdour, Youssef, Bruat, Vanessa, de Maillard, Thibault, Grenier, Jean-Christophe, Grenier, Jean-Cristophe, Gbeha, Elias, Hamdan, Fadi F, Girard, Simon, Spinella, Jean-François, Larivière, Mathieu, Saillour, Virginie, Healy, Jasmine, Fernández, Isabel, Sinnett, Daniel, Michaud, Jacques L, Rouleau, Guy A, Haddad, Elie, Le Deist, Françoise, Awadalla, Philip

“…Whole-exome or gene targeted resequencing in hundreds to thousands of individuals has shown that the majority of genetic variants are at low frequency in human…”
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Promoter SNPs in G1/S checkpoint regulators and their impact on the susceptibility to childhood leukemia by Healy, Jasmine, Bélanger, Hélène, Beaulieu, Patrick, Larivière, Mathieu, Labuda, Damian, Sinnett, Daniel

“…Mutations leading to the alteration of cell-cycle checkpoint functions are a common feature of most cancers. Because of the highly regulated nature of the cell…”
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In vivo footprinting analysis of the Glypican 3 (GPC3) promoter region in neuroblastoma cells by Boily, Gino, Ouellet, Stéphane, Langlois, Sylvie, Larivière, Mathieu, Drouin, Régen, Sinnett, Daniel

“…Glypican 3 (GPC3) is an X-linked gene that has its peak expression during development and is down-regulated in all studied tissues after birth. We have shown…”
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Promoter polymorphisms in CHI3L1 are associated with asthma by Verlaan, Dominique J., PhD, Ouimet, Manon, MSc, Adoue, Veronique, MSc, Sirois-Gagnon, Dave, MSc, Larivière, Mathieu, MSc, Ge, Bing, MSc, Beaulieu, Patrick, MSc, Dias, Joana, MEng, Lam, Kevin C.L., MSc, Koka, Vonda, MSc, Laprise, Catherine, PhD, Pastinen, Tomi, MD, PhD, Sinnett, Daniel, PhD

“…[...]we tested the association of the rs4950928 and rs10399931 SNPs with asthma in a Saguenay-Lac-Saint-Jean asthmatic familial collection, which comprises 253…”
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Abstract 4416: Rapid, low-input, targeted NGS workflow for DNA methylation by Pickle, Loni, Hatch, Andrew, Yavas, Gokhan, Spears, Melanie, Gasparini, Louis, Talebian, Vida, Lee, Anna Ying-Wah, Lariviere, Mathieu, Bayani, Jane, Sadis, Seth, Smith, Jeffrey M.

“…DNA methylation is a fundamental epigenetic process that regulates human gene expression. In cancer, methylation changes promote proliferation networks and…”
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25. Towards a clinical grade NGS assay for DNA hypermethylation in prostate cancer by Patel, Palak G., Pickle, Loni, Hatch, Andrew G, Fergusson, Nathan, Archer, Nicole, Zhang, Xiao, Lariviere, Mathieu, Gooding, Robert J., Berman, David M.

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Effects of atorvastatin on electrophoretic characteristics of LDL particles among subjects with heterozygous familial hypercholesterolemia by Larivière, Mathieu, Lamarche, Benoı̂t, Pirro, Matteo, Hogue, Jean-Charles, Bergeron, Jean, Gagné, Claude, Couture, Patrick

“…The effects of the HMG CoA reductase inhibitor atorvastatin on electrophoretic characteristics of LDL particles were evaluated in 46 patients (28 males and 18…”
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Abstract 5548: Clinical management and decision making in early ER-positive breast cancers through improved prognosis and pathway directed molecular profiling by Bartlett, John M., Crozier, Cheryl, Mittal, Vinay K., Dion, Dan, Luca, Angela De, Sundby, Adam E., Woroszchuk, Elizabeth, d’Souza, Bradley, Gasparini, Louis, Quintayo, Mary Anne, Chahal, Mehar, Lee, Anna Y., Larivière, Mathieu, Park, Kyusung S., Sharma, Anupma, Smith, Jeffrey M., Sadis, Seth, Rea, Daniel W., Spears, Melanie, Bayani, Jane

“…Hormone receptor positive (HR+ve) breast cancer (BCa) comprises over 80% of all newly diagnosed BCas. While there is an initial good response to anti-hormone…”
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Abstract 2484: Whole-exome sequencing of a rare case of familial childhood acute lymphoblastic leukemia by Healy, Jasmine, Saillour, Virginie, Spinella, Jean-François, Vidal, Ramon, Bareke, Eric, Richer, Chantal, Larivière, Mathieu, Busche, Stephan, Ge, Bing, Montpetit, Alexandre, Pastinen, Tomi, Sinnett, Daniel

“…Acute lymphoblastic leukemia (ALL) is the most common cancer in children, accounting for approximately 25% of all pediatric cancer cases. However, familial…”
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Whole-Exome Sequencing Reveals a Rapid Change in the Frequency of Rare Functional Variants in a Founding Population of Humans: e1003815 by Casals, Ferran, Hodgkinson, Alan, Hussin, Julie, Idaghdour, Youssef, Bruat, Vanessa, Maillard, Thibault de, Grenier, Jean-Cristophe, Gbeha, Elias, Hamdan, Fadi F, Girard, Simon, Spinella, Jean-François, Larivière, Mathieu, Saillour, Virginie, Healy, Jasmine, Fernández, Isabel, Sinnett, Daniel, Michaud, Jacques L, Rouleau, Guy A, Haddad, Elie, Deist, Françoise Le, Awadalla, Philip

“…Whole-exome or gene targeted resequencing in hundreds to thousands of individuals has shown that the majority of genetic variants are at low frequency in human…”
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Abstract 4335: The genomic landscape of childhood pre-B acute lymphoblastic leukemia by Spinella, Jean-François, Saillour, Virginie, Richer, Chantal, Ouimet, Manon, Cassart, Pauline, Healy, Jasmine, Bareke, Eric, Larivière, Mathieu, St-Onge, Pascal, Busche, Stephan, Ge, Bing, Montpetit, Alexandre, Pastinen, Tomi, Sinnett, Daniel

“…Precursor B-cell acute lymphoblastic leukemia (pre-B ALL) is the most frequent pediatric cancer. Increased understanding of the pathobiology of B-cell ALL has…”
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