Search Results - "Larimer, M"

Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy by Larimer, Benjamin M, Wehrenberg-Klee, Eric, Caraballo, Alexander, Mahmood, Umar

“…Immune checkpoint inhibitors have made rapid advances, resulting in multiple Food and Drug Administration-approved therapeutics that have markedly improved…”
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Granzyme B PET Imaging as a Predictive Biomarker of Immunotherapy Response by Larimer, Benjamin M, Wehrenberg-Klee, Eric, Dubois, Frank, Mehta, Anila, Kalomeris, Taylor, Flaherty, Keith, Boland, Genevieve, Mahmood, Umar

“…While cancer immunotherapy can produce dramatic responses, only a minority of patients respond to treatment. Reliable response biomarkers are needed to…”
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18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition by Reeves, Kirsten M., Song, Patrick N., Angermeier, Allyson, Manna, Deborah Della, Li, Yufeng, Wang, Jianbo, Yang, Eddy S., Sorace, Anna G., Larimer, Benjamin M.

“…PURPOSEHypoxia is a common characteristic of many tumor microenvironments, and it has been shown to promote suppression of antitumor immunity. Despite strong…”
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Evaluating the immunologically "cold" tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4 + and CD8 + T cells in breast cancer mouse models by Lu, Yun, Houson, Hailey A, Gallegos, Carlos A, Mascioni, Alessandro, Jia, Fang, Aivazian, Argin, Song, Patrick N, Lynch, Shannon E, Napier, Tiara S, Mansur, Ameer, Larimer, Benjamin M, Lapi, Suzanne E, Hanker, Ariella B, Sorace, Anna G

“…Immune-positron emission tomography (PET) imaging with tracers that target CD8 and granzyme B has shown promise in predicting the therapeutic response…”
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Phage Display Selection, In Vitro Characterization, and Correlative PET Imaging of a Novel HER3 Peptide by Larimer, Benjamin M., Phelan, Nicholas, Wehrenberg-Klee, Eric, Mahmood, Umar

“…Purpose HER3 (ERBB3) is a receptor tyrosine kinase that is implicated in treatment resistance across multiple cancers, including those of the breast, lung, and…”
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[ 89 Zr]-Pertuzumab PET Imaging Reveals Paclitaxel Treatment Efficacy Is Positively Correlated with HER2 Expression in Human Breast Cancer Xenograft Mouse Models by Lu, Yun, Li, Meng, Massicano, Adriana V F, Song, Patrick N, Mansur, Ameer, Heinzman, Katherine A, Larimer, Benjamin M, Lapi, Suzanne E, Sorace, Anna G

“…Paclitaxel (PTX) treatment efficacy varies in breast cancer, yet the underlying mechanism for variable response remains unclear. This study evaluates whether…”
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Exposure of progressive immune dysfunction by SARS-CoV-2 mRNA vaccination in patients with chronic lymphocytic leukemia: A prospective cohort study by Qin, Kai, Honjo, Kazuhito, Sherrill-Mix, Scott, Liu, Weimin, Stoltz, Regina M, Oman, Allisa K, Hall, Lucinda A, Li, Ran, Sterrett, Sarah, Frederick, Ellen R, Lancaster, Jeffrey R, Narkhede, Mayur, Mehta, Amitkumar, Ogunsile, Foluso J, Patel, Rima B, Ketas, Thomas J, Cruz Portillo, Victor M, Cupo, Albert, Larimer, Benjamin M, Bansal, Anju, Goepfert, Paul A, Hahn, Beatrice H, Davis, Randall S

“…Patients with chronic lymphocytic leukemia (CLL) have reduced seroconversion rates and lower binding antibody (Ab) and neutralizing antibody (NAb) titers than…”
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When the party continues: Impulsivity and the effect of employment on young adults' post-college alcohol use by Geisner, I.M., Koopmann, J., Bamberger, P., Wang, M., Larimer, M.E., Nahum-Shani, I., Bacharach, S.

“…The transition from college to work is both an exciting and potentially high risk time for young adults. As students transition from academic settings to…”
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Preclinical PET Imaging of Granzyme B Shows Promotion of Immunological Response Following Combination Paclitaxel and Immune Checkpoint Inhibition in Triple Negative Breast Cancer by Napier, Tiara S, Hunter, Chanelle L, Song, Patrick N, Larimer, Benjamin M, Sorace, Anna G

“…Advancements in monitoring and predicting of patient-specific response of triple negative breast cancer (TNBC) to immunotherapy (IMT) with and without…”
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PET Imaging for Monitoring Cellular and Immunotherapy of Cancer by Larimer, Benjamin M

“…Cancer immunotherapy, including checkpoint blockade and cellular therapy, has become a cornerstone in cancer treatment. However, understanding the factors…”
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Screening and Brief Intervention for High-Risk College Student Drinkers: Results From a 2-Year Follow-Up Assessment by Marlatt, G. Alan, Baer, John S, Kivlahan, Daniel R, Dimeff, Linda A, Larimer, Mary E, Quigley, Lori A, Somers, Julian M, Williams, Ellen

“…This randomized controlled trial evaluated the efficacy of a brief intervention designed to reduce the harmful consequences of heavy drinking among high-risk…”
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PTSD symptoms, substance use, and vipassana meditation among incarcerated individuals by Simpson, T. L., Kaysen, D., Bowen, S., MacPherson, L. M., Chawla, N., Blume, A., Marlatt, G. A., Larimer, M.

“…The present study evaluated whether Posttraumatic Stress Disorder (PTSD) symptom severity was associated with participation and treatment outcomes comparing a…”
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Reporter Genes for PET Imaging of CAR-T Cells Offers Insight into Adoptive Cell Transfer by Larimer, Benjamin M

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The Effectiveness of Checkpoint Inhibitor Combinations and Administration Timing Can Be Measured by Granzyme B PET Imaging by Larimer, Benjamin M, Bloch, Emily, Nesti, Sarah, Austin, Emily E, Wehrenberg-Klee, Eric, Boland, Genevieve, Mahmood, Umar

“…The lack of a timely and reliable measure of response to cancer immunotherapy has confounded understanding of mechanisms of resistance and subsequent…”
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Imaging of Activated T Cells by Sako, Mohammad O, Larimer, Benjamin M

“…The adaptive immune response plays a critical role in detecting, eliminating, and creating a memory toward foreign pathogens and malignant cells. Demonstration…”
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Male and female recipients of unwanted sexual contact in a college student sample : Prevalence rates, alcohol use, and depression symptoms by LARIMER, M. E, LYDUM, A. R, ANDERSON, B. K, TURNER, A. P

“…It is typically assumed that acquaintance rape and other forms of unwanted sexual contact involve males as perpetrators and females as victims. The current…”
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Evaluation of [89Zr]Zr-DFO-2Rs15d Nanobody for Imaging of HER2-Positive Breast Cancer by Ducharme, Maxwell, Hall, Lucinda, Eckenroad, Whitney, Cingoranelli, Shelbie J., Houson, Hailey A., Jaskowski, Luke, Hunter, Chanelle, Larimer, Benjamin M., Lapi, Suzanne E.

“…One of the most aggressive forms of breast cancer involves the overexpression of human epidermal growth factor receptor 2 (HER2). HER2 is overexpressed in ∼25%…”
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[18F]FMISO-PET imaging reveals the role of hypoxia severity in checkpoint blockade response by McNeal, Kaytlyn C., Reeves, Kirsten M., Song, Patrick N., Lapi, Suzanne E., Sorace, Anna G., Larimer, Benjamin M.

“…Hypoxia within the tumor microenvironment is a critical factor influencing the efficacy of immunotherapy, including immune checkpoint inhibition. Insufficient…”
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92418 Molecular imaging of the tumor microenvironment to predict response to combination treatment with immunotherapy in triple negative breast cancer by Napier, Tiara S., Hunter, Chanelle L., Song, Patrick N., Larimer, Benjamin M., Sorace, Anna G.

“…ABSTRACT IMPACT: Insights from this project will provide clinical guidance in treatment of immunotherapy in triple negative breast cancer and identify early…”
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Comprehensive mapping of SARS-CoV-2 peptide epitopes for development of a highly sensitive serological test for total and neutralizing antibodies by Kumar, Garima, Sterrett, Sarah, Hall, Lucinda, Tabengwa, Edlue, Honjo, Kazuhito, Larimer, Michael, Davis, Randall S, Goepfert, Paul A, Larimer, Benjamin M

“…Abstract Quantification of the anti-SARS-CoV-2 antibody response has proven to be a prominent diagnostic tool during the COVID-19 pandemic. Antibody…”
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