Search Results - "Largounez, Amelie"

Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR by Belot, Audrey, Gourbeyre, Ophélie, Palin, Anais, Rubio, Aude, Largounez, Amélie, Besson-Fournier, Céline, Latour, Chloé, Lorgouilloux, Megane, Gallitz, Inka, Montagner, Alexandra, Polizzi, Arnaud, Régnier, Marion, Smati, Sarra, Zhang, An-Sheng, Diaz-Munoz, Manuel D, Steinbicker, Andrea U, Guillou, Hervé, Roth, Marie-Paule, Coppin, Hélène, Meynard, Delphine

“…The liver hormone hepcidin controls the main inflows of iron into plasma by binding to and inducing the degradation or the occlusion of the iron export…”
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A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice by Wake, Matthew, Palin, Anaïs, Belot, Audrey, Berger, Mathieu, Lorgouilloux, Megane, Bichon, Margot, Papworth, Jonathan, Bayliss, Luke, Grimshaw, Benjamin, Rynkiewicz, Natalie, Paterson, Jemima, Poindron, Alicia, Spearing, Erin, Carter, Emily, Hudson, Robyne, Campbell, Millie, Petzer, Verena, Besson-Fournier, Céline, Latour, Chloé, Largounez, Amélie, Gourbeyre, Ophélie, Fay, Alexis, Coppin, Hélène, Roth, Marie-Paule, Theurl, Igor, Germaschewski, Volker, Meynard, Delphine

“…•RLYB331 is a human antibody that increases hepcidin, reduces iron overload, and ameliorates ineffective erythropoiesis in β-thalassemia•Combination with…”
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Generation and Characterisation of KY1066, a Fully Human Antibody Targeting the Enzymatic Activity of Matriptase-2 for the Treatment of Iron Overload in Beta Thalassemia by Wake, Matthew, Papworth, Jonathan, Bayliss, Luke, Grimshaw, Benjamin, Rynkiewicz, Natalie, Paterson, Jemima, Poindron, Alicia, Spearing, Erin, Carter, Emily, Hudson, Robyne, Petzer, Verena, Largounez, Amelie, Belot, Audrey, Palin, Anais, Theurl, Igor, Germaschewski, Volker, Meynard, Delphine

“…Beta thalassemia is an inherited hemoglobinopathy caused by a genetic defect in beta-globin gene and characterised by ineffective erythropoiesis, iron…”
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