Search Results - "Largent, A."

A Framework for Ethical Payment to Research Participants by Gelinas, Luke, Largent, Emily A, Cohen, I. Glenn, Kornetsky, Susan, Bierer, Barbara E, Fernandez Lynch, Holly

“…The authors propose a framework for evaluating the appropriateness of payments to research participants. They distinguish three acceptable rationales for…”
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Cognitively unimpaired adults' reactions to disclosure of amyloid PET scan results by Largent, Emily A, Harkins, Kristin, van Dyck, Christopher H, Hachey, Sara, Sankar, Pamela, Karlawish, Jason

“…Clinical guidelines currently recommend against amyloid imaging for cognitively unimpaired persons. The goal of Alzheimer's disease (AD) prevention, together…”
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Deep learning methods to generate synthetic CT from MRI in radiotherapy: A literature review by Boulanger, M., Nunes, Jean-Claude, Chourak, H., Largent, A., Tahri, S., Acosta, O., De Crevoisier, R., Lafond, C., Barateau, A.

“…•Review of deep learning approaches to generate synthetic-CTs for MRI-based dose calculation.•Overview and discussion of image and dose metrics for…”
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Automated 3D Fetal Brain Segmentation Using an Optimized Deep Learning Approach by Zhao, L, Asis-Cruz, J D, Feng, X, Wu, Y, Kapse, K, Largent, A, Quistorff, J, Lopez, C, Wu, D, Qing, K, Meyer, C, Limperopoulos, C

“…MR imaging provides critical information about fetal brain growth and development. Currently, morphologic analysis primarily relies on manual segmentation,…”
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Study partners: essential collaborators in discovering treatments for Alzheimer's disease by Largent, Emily A, Karlawish, Jason, Grill, Joshua D

“…Global leaders have set an ambitious goal of developing interventions to effectively treat or prevent Alzheimer's disease by 2025. Achieving this goal will…”
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From an idea to the marketplace: Identifying and addressing ethical and regulatory considerations across the digital health product-development lifecycle by Largent, Emily A, Karlawish, Jason, Wexler, Anna

“…Widespread adoption of digital health tools has the potential to improve health and health care for individuals and their communities, but realizing this…”
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A high-performance method of deep learning for prostate MR-only radiotherapy planning using an optimized Pix2Pix architecture by Tahri, S., Barateau, A., Cadin, C., Chourak, H., Ribault, S., Nozahic, F., Acosta, O., Dowling, J.A., Greer, P.B., Largent, A., Lafond, C., De Crevoisier, R., Nunes, J.C.

“…•A competitive method of deep learning (Pix2Pix) for prostate MR-only radiotherapy.•Significant variation in image evaluation depending on several…”
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How well can we assess the validity of non-randomised studies of medications? A systematic review of assessment tools by D'Andrea, Elvira, Vinals, Lydia, Patorno, Elisabetta, Franklin, Jessica M., Bennett, Dimitri, Largent, Joan A., Moga, Daniela C., Yuan, Hongbo, Wen, Xuerong, Zullo, Andrew R., Debray, Thomas P. A., Sarri, Grammati

“…ObjectiveTo determine whether assessment tools for non-randomised studies (NRS) address critical elements that influence the validity of NRS findings for…”
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Efficient burdens decrease nonmedical exemption rates: A cross-county comparison of Michigan’s vaccination waiver education efforts by Navin, Mark C., Largent, Mark A., McCright, Aaron M.

“…Michigan’s introduction of mandatory counseling for nonmedical exemptions was associated with decreased nonmedical exemption rates. However, while each of…”
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Deciding with Others: Interdependent Decision‐Making by Largent, Emily A., Clapp, Justin, Blumenthal‐Barby, Jennifer S., Grady, Christine, McGuire, Amy L., Karlawish, Jason, Grill, Joshua D., Stites, Shana D., Peterson, Andrew

“…Over the course of human life, health care decision‐making is often interdependent. In this article, we use “interdependence” to refer to patients’ engagement…”
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Head-and-Neck MRI-only radiotherapy treatment planning: From acquisition in treatment position to pseudo-CT generation by Largent, A., Marage, L., Gicquiau, I., Nunes, J.-C., Reynaert, N., Castelli, J., Chajon, E., Acosta, O., Gambarota, G., de Crevoisier, R., Saint-Jalmes, H.

“…In context of head-and-neck radiotherapy, this study aims to compare MR image quality according to diagnostic (DIAG) and radiotherapy (RT) setups; and to…”
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Ethics of reallocating ventilators in the covid-19 pandemic by Peterson, Andrew, Largent, Emily A, Karlawish, Jason

“…Andrew Peterson and colleagues explore ways to protect vulnerable populations when making ethically fraught decisions about use of scarce resources…”
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Public Health, Racism, and the Lasting Impact of Hospital Segregation by Largent, Emily A.

“…In recent years, a growing number of calls have been made to explicitly name and treat racism as a determinant of health. Mounting evidence support the notion…”
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Problems With Paying People to Be Vaccinated Against COVID-19 by Largent, Emily A, Miller, Franklin G

“…This Viewpoint describes features of 2 proposals to pay US residents to be vaccinated against COVID-19 and proposes ethical and practical complications of the…”
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The Future Is P-Tau-Anticipating Direct-to-Consumer Alzheimer Disease Blood Tests by Largent, Emily A, Wexler, Anna, Karlawish, Jason

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Supported decision making: Facilitating the self-determination of persons living with Alzheimer's and related diseases by Largent, Emily A, Peterson, Andrew, Karlawish, Jason

“…Decision-making capacity describes the ability to make a particular decision at a given time. People with Mild Cognitive Impairment (MCI) and mild stage…”
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Consent to Trainee Involvement in Pediatric Care by Largent, Emily A

“…Consent to the involvement of students, interns, and residents in the care of children has received scant attention as compared with consent for either care or…”
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A survey instrument for measuring vaccine acceptance by Sarathchandra, Dilshani, Navin, Mark C., Largent, Mark A., McCright, Aaron M.

“…Accurately measuring vaccine acceptance is important, especially under current conditions in which misinformation may increase public anxiety about vaccines…”
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Heightism, growth hormone treatment, and social functioning: a holistic approach to a persistent clinical challenge by Kamoun, Camilia, Largent, Emily A, Grimberg, Adda

“…Use of recombinant human growth hormone (rhGH) treatment to increase height in children with non-growth hormone deficient short stature is becoming more…”
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Testing for Alzheimer Disease Biomarkers and Disclosing Results Across the Disease Continuum by Largent, Emily A., Grill, Joshua D., O'Brien, Kyra, Wolk, David, Harkins, Kristin, Karlawish, Jason

“…Three pathologic processes are characteristic of Alzheimer disease (AD)β-amyloid, hyperphosphorylated tau, and neurodegeneration. Our understanding of AD is…”
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