Search Results - "Lareu, R R"

The Scar‐in‐a‐Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well by Chen, CZC, Peng, YX, Wang, ZB, Fish, PV, Kaar, JL, Koepsel, RR, Russell, AJ, Lareu, RR, Raghunath, M

“…Background and purpose:  Fibrosis, a pathological accumulation of collagen in tissues, represents a major global disease burden. Effective characterization of…”
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Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism by Caparrós-Martín, Jose A, Lareu, Ricky R, Ramsay, Joshua P, Peplies, Jörg, Reen, F Jerry, Headlam, Henrietta A, Ward, Natalie C, Croft, Kevin D, Newsholme, Philip, Hughes, Jeffery D, O'Gara, Fergal

“…Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing…”
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Suberoylanilide hydroxamic acid: a potential epigenetic therapeutic agent for lung fibrosis? by Wang, Z, Chen, C, Finger, S. N, d/o Kwajah M.M, S, Jung, M, Schwarz, H, Swanson, N, Lareu, R. R, Raghunath, M

“…Pulmonary fibrosis represents a fatal stage of interstitial lung diseases of known and idiopathic aetiology. No effective therapy is currently available. Based…”
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In vitro antibacterial effects of statins against bacterial pathogens causing skin infections by Ko, Humphrey H. T., Lareu, Ricky R., Dix, Brett R., Hughes, Jeffery D.

“…With financial considerations impeding research and development of new antibiotics, drug repurposing (finding new indications for old drugs) emerges as a…”
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Statins: antimicrobial resistance breakers or makers? by Ko, Humphrey H T, Lareu, Ricky R, Dix, Brett R, Hughes, Jeffery D

“…The repurposing of non-antibiotic drugs as adjuvant antibiotics may help break antimicrobial resistance (AMR). Statins are commonly prescribed worldwide to…”
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Essential modification of the Sircol Collagen Assay for the accurate quantification of collagen content in complex protein solutions by Lareu, Ricky R., Zeugolis, Dimitrios I., Abu-Rub, Mohammad, Pandit, Abhay, Raghunath, Michael

“…Collagen contains the unique imino acid hydroxyproline (HyPro), which is involved in the stabilization of this triple helical molecule. The concentration of…”
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Collagen solubility testing, a quality assurance step for reproducible electro-spun nano-fibre fabrication. A technical note by Zeugolis, D. I., Li, B., Lareu, R. R., Chan, C. K., Raghunath, M.

“…Collagen is the main component of the extra-cellular matrix and has been utilised for numerous clinical applications in many forms and products. However, since…”
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Role of DDC-4 sFRP-4, a secreted Frizzled-related protein, at the onset of apoptosis in mammary involution by Lacher, M D, Siegenthaler, A, Jäger, R, Yan, Xi, Hett, S, Xuan, L, Saurer, S, Lareu, R R, Dharmarajan, A M, Friis, R

“…Using differential display, we isolated DDC-4, a secreted frizzled-related protein (sFRP), which is induced in the physiological apoptosis of hormonally…”
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Emulating a crowded intracellular environment in vitro dramatically improves RT-PCR performance by Lareu, Ricky R., Harve, Karthik S., Raghunath, Michael

“…The polymerase chain reaction’s (PCR) phenomenal success in advancing fields as diverse as Medicine, Agriculture, Conservation, or Paleontology is based on the…”
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A histological and micro-CT investigation in to the effect of NGF and EGF on the periodontal, alveolar bone, root and pulpal healing of replanted molars in a rat model - a pilot study by Furfaro, Francesco, Ang, Estabelle SM, Lareu, Ricky R, Murray, Kevin, Goonewardene, Mithran

“…Background This study aims to investigate, utilising micro-computed tomography (micro-CT) and histology, whether the topical application of nerve growth factor…”
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Fas and Fas Ligand Messenger Ribonucleic Acid and Protein Expression in the Rat Corpus Luteum during Apoptosis-Mediated Luteolysis by ROUGHTON, S. A, LAREU, R. R, BITTLES, A. H, DHARMARAJAN, A. M

“…Apoptosis has been found to occur during regression of the corpus luteum (CL) in many species. The Fas (APO-1/CD95) receptor, a transmembrane protein that…”
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Early adhesive behavior of bone-marrow-derived mesenchymal stem cells on collagen electrospun fibers by Chan, Casey K, Liao, Susan, Li, Bojun, Lareu, Ricky R, Larrick, James W, Ramakrishna, S, Raghunath, Michael

“…A bioabsorbable nanofibrous scaffold was developed for early adhesion of mesenchymal stem cells (MSCs). Collagen nanofibers with diameters of 430 +/- 170 nm…”
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In vitro enhancement of collagen matrix formation and crosslinking for applications in tissue engineering: a preliminary study by Lareu, Ricky R, Arsianti, Irma, Subramhanya, Harve Karthik, Yanxian, Peng, Raghunath, Michael

“…The construction of stable engineered tissue depends on the formation of a functional connective tissue produced by cells locally. A major component of…”
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Inhibition of nitric oxide synthesis potentiates apoptosis in the rabbit corpus luteum by Preutthipan, S, Chen, SH, Tilly, JL, Kugu, K, Lareu, RR, Dharmarajan, AM

“…To determine if nitric oxide (NO) plays a role in corpus luteum (CL) physiology by affecting progesterone secretion or luteal apoptosis, an in-vitro…”
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A sequence symmetry analysis of the interrelationships between statins, diabetes and skin infections by Ko, Humphrey H.T., Lareu, Ricky R., Dix, Brett R., Hughes, Jeffery D., Parsons, Richard W.

“…Aims To determine statins' impact on skin infection risk in view of conflicting literature: that statins may reduce infection risk, but are also associated…”
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Collagen matrix deposition is dramatically enhanced in vitro when crowded with charged macromolecules: The biological relevance of the excluded volume effect by Lareu, Ricky R., Subramhanya, Karthik Harve, Peng, Yanxian, Benny, Paula, Chen, Clarice, Wang, Zhibo, Rajagopalan, Raj, Raghunath, Michael

“…The excluded volume effect (EVE) rules all life processes. It is created by macromolecules that occupy a given volume thereby confining other molecules to the…”
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Effect of Statins on Sepsis Outcome in a Population-Based Cohort Study by Ko, Humphrey H.T., Lareu, Ricky R., Dix, Brett R., Hughes, Jeffery D.

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Protein markers for Alzheimer disease in the frontal cortex and cerebellum by VERDILE, G, GNJEC, A, LAREU, R, LIM, D, DHARMARAJAN, A, MARTINS, R. N, MIKLOSSY, J, FONTE, J, VEURINK, G, BATES, K, KAKULAS, B, MEHTA, P. D, MILWARD, E. A, TAN, N

“…To compare proteins related to Alzheimer disease (AD) in the frontal cortex and cerebellum of subjects with early-onset AD (EOAD) with or without presenilin 1…”
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Statin Use Associated With a Decreased Risk of Community-Acquired Staphylococcus aureus Bacteremia by Ko, Humphrey H.T., Lareu, Ricky R., Dix, Brett R., Hughes, Jeffery D.

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Role of apoptosis in functional luteolysis in the pregnant rabbit corpus luteum: evidence of a role for placental-derived factors in promoting luteal cell survival by Dharmarajan, A M, Goodman, S B, Atiya, N, Parkinson, S P, Lareu, R R, Tilly, K I, Tilly, J L

“…Corpora lutea (CL) were isolated from one rabbit ovary on days 4, 8, 16 (peak luteal function), 28 (functional regression) and 30 of pregnancy and processed…”
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