Search Results - "Laresgoiti, Usua"
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Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
Published in eLife (30-06-2017)“…The embryonic mouse lung is a widely used substitute for human lung development. For example, attempts to differentiate human pluripotent stem cells to lung…”
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E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes
Published in Nucleic acids research (01-12-2013)“…E2F2 is essential for the maintenance of T lymphocyte quiescence. To identify the full set of E2F2 target genes, and to gain further understanding of the role…”
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Multiple E2F-Induced MicroRNAs Prevent Replicative Stress in Response to Mitogenic Signaling
Published in Molecular and Cellular Biology (01-06-2010)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Development of a genetically modifiable epithelial in-vitro culture system from human embryonic lung epithelial stem cells: towards human lung regeneration in end-stage respiratory failure
Published in The Lancet (British edition) (23-02-2017)“…Abstract Background Regeneration of healthy lung tissue in patients with end-stage respiratory disease would cure disease. Therefore, a detailed understanding…”
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E2F2 represses cell cycle regulators to maintain quiescence
Published in Cell cycle (Georgetown, Tex.) (15-12-2008)“…E2F transcription factors control diverse biological processes through regulation of target gene expression. However, the mechanism by which this regulation…”
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Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice
Published in The Journal of clinical investigation (15-05-2004)“…E2F transcription factors are thought to be key regulators of cell growth control. Here we use mutant mouse strains to investigate the function of E2F1 and…”
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Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate
Published in Development (Cambridge) (15-10-2016)“…Insufficient alveolar gas exchange capacity is a major contributor to lung disease. During lung development, a population of distal epithelial progenitors…”
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Differential Proteomics Analysis Reveals a Role for E2F2 in the Regulation of the Ahr Pathway in T Lymphocytes
Published in Molecular & cellular proteomics (01-10-2010)“…E2F transcription factors (E2F1-8) are best known for their role in cell proliferation, although it is clear that they regulate many other biological processes…”
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