Search Results - "Larenkov, A. A."

Selection and Use of Antioxidants-radioprotectors in the Composition of Therapeutic Radiopharmaceuticals (Review) by Pavlenko, E. P., Larenkov, A. A., Mitrofanov, Iu. A.

“…Introduction. The use of radiopharmaceuticals for targeted radionuclide therapy (TRT), the efficacy of which was established during clinical trials, is safe…”
Get full text

Features and Practical Aspects of Radiochemical Purity Determination of Receptor-Specific Lu-177 Radiopharmaceuticals as Exemplified by [177Lu]Lu–PSMA-617 by Larenkov, A. A., Mitrofanov, Yu. A., Rakhimov, M. G.

“…Radiochemical purity (RCP) is one of the key quality criteria for radiopharmaceuticals (RPs) used in clinical practice. The results of RCP measurements depend…”
Get full text

Chelating Agents for Zirconium-89 in the Synthesis of Radiopharmaceuticals: Current State and Prospects of Development by Bubenshchikov, V. B., Larenkov, A. A.

“…Zirconium is a highly demanded element widely used in various fields of science and technology. There are 39 known zirconium isotopes, among which zirconium-89…”
Get full text

Possible Impurities in Radiopharmaceuticals and Corresponding Test Methods by Kodina, G. E., Malysheva, A. O., Larenkov, A. A., Bruskin, A. B.

“…The main quality attributes of radiopharmaceuticals that ensure their effectiveness and safety and are unique to their specifications are activity,…”
Get full text

Biodistribution of Mesenchymal Stromal Cells Labeled with [89Zr]Zr-Oxine in Local Radiation Injuries in Laboratory Animals by Astrelina, Tatiana A., Brunchukov, Vitaliy A., Kodina, Galina E., Bubenshchikov, Viktor B., Larenkov, Anton A., Lunev, Aleksandr S., Petrosova, Kristina A., Rastorgueva, Anna A., Kobzeva, Irina V., Usupzhanova, Daria Y., Nikitina, Victoria A., Malsagova, Kristina A., Kulikova, Ludmila I., Samoilov, Alexander S., Pustovoyt, Vasiliy I.

“…Background: Tracking the migration pathways of living cells after their introduction into a patient’s body is a topical issue in the field of cell therapy…”
Get full text

Evaluation of the Applicability of External X-ray Radiation to Stimulate the Autoradiolysis Processes in Therapeutic Radiopharmaceuticals (Exemplified by [153Sm]Sm-PSMA-617 and [177Lu]Lu-PSMA-617) by Mitrofanov, Yu. A., Bubenshchikov, V. B., Belousov, A. V., Lunev, A. S., Larenkov, A. A.

“…The paper presents the results of a study on the radiolytic degradation of vector molecules in radiopharmaceuticals, caused by ionizing radiation from the…”
Get full text

Preparation of 89Zr Solutions for Radiopharmaceuticals Synthesis by Bubenshchikov, V. B., Larenkov, A. A., Kodina, G. E.

“…Zirconium-89 is a promising radionuclide for nuclear medicine and has optimal nuclear-physical parameters for study of processes with slow kinetic. The…”
Get full text

Erratum to: Evaluation of the Applicability of External X-ray Radiation to Simulate the Autoradiolysis Processes in Therapeutic Radiopharmaceuticals (Exemplified by [153Sm]Sm-PSMA-617 and [177Lu]Lu-PSMA-617) by Mitrofanov, Yu. A., Bubenshchikov, V. B., Belousov, A. V., Lunev, A. S., Larenkov, A. A.

“…An Erratum to this paper has been published: https://doi.org/10.1134/S0018143923310016…”
Get full text

Radiation stability of carboxymethylcellulose microgels cross-linked by copper ions by Orlova, M. A., Trofimova, T. P., Zolotova, A. S., Larenkov, A. A., Orlov, A. P., Borodkov, A. A., Spiridonov, V. V.

“…Carboxymethylcellulose (CMC) complexes cross-linked with copper ions exhibit radiation stability, up to high doses of radiation (∼2000 Gy). A model estimate of…”
Get full text

Intricacies of the Determination of the Radiochemical Purity of 68Ga Preparations: Possibility of Sorption of Ionic 68Ga Species on Reversed-Phase Columns by Larenkov, A. A., Maruk, A. Ya, Kodina, G. E.

“…The results of studying 68 Ga radiopharmaceuticals using various TLC and HPLC procedures are compared. The data obtained reliably show that a part of 68 Ga…”
Get full text

Evaluation of Applicability of Aminodiphosphonic Acids for the Development of Bone-Seeking 68Ga-Radiopharmaceuticals by Mitrofanov, Iu. A., Maruk, A. Ya, Larenkov, A. A., Kodina, G. E., Lunev, A. S., Luneva, K. A., Klementyeva, O. E., Tsebrikova, G. S., Baulin, V. E., Ragulin, V. V., Tsivadze, A. Yu

“…The binding of 68 Ga to two organic ligands containing aminodiphosphonic groups (1,7-diamino-4-oxaheptane-1,1,7,7-tetraphosphonic and…”
Get full text

2,5-Diamino-5,5-diphosphonovaleric Acid as a Ligand for an Osteotropic 188Re Radiopharmaceutical by Tsebrikova, G. S., Ragulin, V. V., Baulin, V. E., German, K. E., Malysheva, A. O., Klement’eva, O. E., Kodina, G. E., Larenkov, A. A., Lyamtseva, E. A., Taratonenkova, N. A., Zhukova, M. V., Tsivadze, A. Yu

“…A modified method for the preparation of 2,5-diamino-5,5-diphosphonovaleric acid (DADP5) has been developed in the search for new synthetically available…”
Get full text

Separation of 44Sc from 44Ti in the Context of A Generator System for Radiopharmaceutical Purposes with the Example of [44Sc]Sc-PSMA-617 and [44Sc]Sc-PSMA-I&T Synthesis by Larenkov, Anton A., Makichyan, Artur G., Iatsenko, Vladimir N.

“…Today, 44Sc is an attractive radionuclide for molecular imaging with PET. In this work, we evaluated a 44Ti/44Sc radionuclide generator based on TEVA resin as…”
Get full text

Determination of ionic 68Ga impurity in radiopharmaceuticals: major revision of radio-HPLC methods by Maruk, Alesya Ya, Larenkov, Anton A.

“…Determination of purity of 68 Ga-radiopharmaceuticals is an extremely important part of quality control in routine clinical practice as well as during R&D of…”
Get full text

Kinetic Study of Folate-Based Radiopharmaceuticals Labeled with 68Ga by Lunev, A. S., Lunyova, K. A., Vasilevich, F. I., Rakhimov, M. G., Larenkov, A. A.

“…Radiopharmaceuticals (RPs) administered intravenously are included into metabolic pathways of the body via binding to carrier molecules, and carrier kinetics…”
Get full text

Complexation of Scandium with Oxabistetramethylenephosphonic Acid and Applicability of Its .sup.44Sc-Labelled Analogue as Bone-Seeking Agent by Mitrofanov, Yu. A, Larenkov, A. A, Kodina, G. E

“…The regularities of complexation of scandium with oxabis(ethylenenitrilo)tetramethylenephosphonic acid (OBEP), which is actively used nowadays in the clinical…”
Get full text

Complexation of Scandium with Oxabis(ethylenenitrilo)tetramethylenephosphonic Acid and Applicability of Its 44Sc-Labelled Analogue as Bone-Seeking Agent by Mitrofanov, Yu. A., Larenkov, A. A., Kodina, G. E.

“…The regularities of complexation of scandium with oxabis(ethylenenitrilo)tetramethylenephosphonic acid (OBEP), which is actively used nowadays in the clinical…”
Get full text

Separation of 44Sc from 44Ti in the Context of A Generator System for Radiopharmaceutical Purposes with the Example of [44Sc]Sc-PSMA-617 and [44Sc]Sc-PSMA-I T Synthesis by Anton A. Larenkov, Artur G. Makichyan, Vladimir N. Iatsenko

“…Today, 44Sc is an attractive radionuclide for molecular imaging with PET. In this work, we evaluated a 44Ti/44Sc radionuclide generator based on TEVA resin as…”
Get full text

Preparation of highly purified 68Ga solutions via ion exchange in hydrochloric acid–ethanol mixtures by Larenkov, A. A., Bruskin, A. B., Kodina, G. E.

“…The ion-exchange behavior of 68 Ga in mixed HCl–ethanol media on cation and anion exchangers was studied. The mass distribution coefficients of 68 Ga on Dowex…”
Get full text

Evaluation of Applicability of Aminodiphosphonic Acids for the Development of Bone-Seeking .sup.68Ga-Radiopharmaceuticals by Mitrofanov, Iu. A, Maruk, A. Ya, Larenkov, A. A, Kodina, G. E, Lunev, A. S, Luneva, K. A, Klementyeva, O. E

“…The binding of .sup.68Ga to two organic ligands containing aminodiphosphonic groups (1,7-diamino-4-oxaheptane-1,1,7,7-tetraphosphonic and…”
Get full text