Search Results - "Lard, L R"

Comparison between 1.5T and 3.0T MRI: both field strengths sensitively detect subclinical inflammation of hand and forefoot in patients with arthralgia by Krijbolder, DI, Verstappen, M, Wouters, F, Lard, LR, de Buck, PDM, Veris-van Dieren, JJ, Bloem, JL, Reijnierse, M, van der Helm-van Mil, AHM

“…Magnetic resonance imaging (MRI) of small joints sensitively detects inflammation. This inflammation, and tenosynovitis in particular, has been shown to…”
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Radiological outcome after four years of early versus delayed treatment strategy in patients with recent onset rheumatoid arthritis by van Aken, J, Lard, L R, le Cessie, S, Hazes, J M W, Breedveld, F C, Huizinga, T W J

“…Objective: To determine the effect of different treatment strategies (early versus delayed) on the radiological progression of joint damage during 4 years…”
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Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis by Tchetverikov, I, Lard, L R, DeGroot, J, Verzijl, N, TeKoppele, J M, Breedveld, F C, Huizinga, T W J, Hanemaaijer, R

“…Objective: To analyse the relation between systemic levels of pro-MMP-3, -8, and -9 matrix metalloproteinase (MMP) activity in α2 macroglobulin (α2M)/MMP…”
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Influence of glucocorticoids and disease activity on total and high density lipoprotein cholesterol in patients with rheumatoid arthritis by Boers, M, Nurmohamed, M T, Doelman, C J A, Lard, L R, Verhoeven, A C, Voskuyl, A E, Huizinga, T W J, van de Stadt, R J, Dijkmans, B A C, van der Linden, Sj

“…Background: Glucocorticoids induce hypercholesterolaemia, a cardiovascular risk factor, in patients with diseases other than rheumatoid arthritis (RA), but the…”
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Neutrophil activation in sickle cell disease by Lard, L. R., Mul, F. P. J., Haas, M., Roos, D., Duits, A. J.

“…Vascular occlusion is the main cause of the morbidity and mortality observed in patients with sickle cell disease (SCD). Increasing evidence indicates that…”
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Miscarriage but not fecundity is associated with progression of joint destruction in rheumatoid arthritis by van Dunné, F M, Lard, L R, Rook, D, Helmerhorst, F M, Huizinga, T W J

“…Objective: To determine whether reproductive history before disease onset is associated with severity of joint destruction in rheumatoid arthritis. Methods: A…”
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Delayed referral of female patients with rheumatoid arthritis by LARD, Leroy R, HUIZINGA, Thomas W. J, HAZES, Johanna M. W, VLIELAND, Theodora P. M. Vliet

“…OBJECTIVE: To analyze whether sex differences in referral exist in patients with rheumatoid arthritis (RA). METHODS: At the Department of Rheumatology of the…”
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Elevated IL-8 levels during sickle cell crisis by Duits, A. J., Schnog, J. B., Lard, L. R., Saleh, A.W., Rojer, R. A.

“…: The vaso‐occlusive process (VOC) in sickle cell disease is of a complex nature. It involves intricate interactions between sickle red blood cells,…”
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A pitfall in screening with decoy cells after simultaneous pancreas kidney transplantation by Lard, L.R., Van Der Boog, P.J.M., Veselic, M., Vossen, A.C.T.M., De Fijter, J.W., Groeneveld, J.H.M.

“…:  In this report, we describe a bladder‐drained simultaneous pancreas‐kidney transplant (SPKT) recipient with a polyoma virus‐associated nephropathy (PVAN) in…”
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Low adjusted‐dose acenocoumarol therapy in sickle cell disease: A pilot study by Schnog, J.B., Kater, A.P., Mac Gillavry, M.R., Duits, A.J., Lard, L.R., van der Dijs, F.P.L., Brandjes, D.P.M., ten Cate, H., Statius van Eps, L.W., Rojer, R.A.

“…Vasoocclusion is a continuous process in sickle cell disease (SCD) and accumulates to significant end organ damage, mostly irrespective of the occurrence of…”
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Comparison of the baseline disease activity of early oligo- and polyarthritis in sequential years by JANSEN, L. M. A, VAN DER HORST-BRUINSMA, I. E, VAN SCHAARDENBURG, D, LARD, L. R, HAZES, J. M. W, HUIZINGA, T. W. J, DIJKMANS, B. A. C

“…Many early arthritis clinics (EACs) have been started in the last decade in order to detect and treat rheumatoid arthritis early. The present study evaluates…”
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Elevated IL-16 levels in patients with systemic lupus erythematosus are associated with disease severity but not with genetic susceptibility to lupus by Lard, L R, Roep, B O, Verburgh, C A, Zwinderman, A H, Huizinga, T W J

“…Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by several immunological abnormalities. The pathogenic importance of T cells in this…”
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Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies by Lard, L R, Visser, H, Speyer, I, vander Horst-Bruinsma, I E, Zwinderman, A H, Breedveld, F C, Hazes, J M

“…To compare the effect of delayed and early treatment strategies on disease outcome in patients with rheumatoid arthritis. Between 1993 and 1995, 109 patients…”
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Association of the –2849 interleukin‐10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis by Lard, L. R., van Gaalen, F. A., Schonkeren, J. J. M., Pieterman, E. J., Stoeken, G., Vos, K., Nelissen, R. G. H. H., Westendorp, R. G. J., Hoeben, R. C., Breedveld, F. C., Toes, R. E. M., Huizinga, T. W. J.

“…Objective To analyze the –2849 A/G interleukin‐10 (IL‐10) promoter polymorphism, which is associated with high (AG/GG) and low (AA) IL‐10 production, in a…”
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Early and aggressive treatment of rheumatoid arthritis patients affects the association of HLA class II antigens with progression of joint damage by Lard, L. R., Boers, M., Verhoeven, A., Vos, K., Visser, H., Hazes, J. M. W., Zwinderman, A. H., Schreuder, G. M. T., Breedveld, F. C., De Vries, R. R. P., Van Der Linden, S., Zanelli, E., Huizinga, T. W. J.

“…Objective The presence of certain HLA class II antigens is strongly associated with the progression of joint destruction in rheumatoid arthritis (RA). Such…”
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New concepts in assessing sickle cell disease severity by Schnog, John‐John B., Lard, Leroy R., Rojer, Robert A., Van der Dijs, Fey P. L., Muskiet, Frits A. J., Duits, Ashley J.

“…Vasoocclusion leads to pain, chronic organ damage, and a decreased life expectancy in patients with sickle cell disease. Therapeutic options for sickle cell…”
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Functional Regulatory Immune Responses against Human Cartilage Glycoprotein-39 in Health vs. Proinflammatory Responses in Rheumatoid Arthritis by Jolanda H. M. van Bilsen, van Dongen, Henrike, Lard, Leroy R., Ellen I. H. van der Voort, Elferink, Diënne G., Bakker, Aleida M., André M. M. Miltenburg, Tom W. J. Huizinga, René R. P. de Vries, René E. M. Toes, van Rood, Johannes

“…The class of immune response against autoantigens could profoundly influence the onset and/or outcome of autoimmune diseases. Until now, there is only limited…”
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Enhanced concentrations of interleukin 16 are associated with joint destruction in patients with rheumatoid arthritis by LARD, Leroy R, ROEP, Bart O, TOES, Rene E. M, HUIZINGA, Thomas W. J

“…OBJECTIVE: To investigate the role of interleukin 16 (IL-16) in the development of rheumatoid arthritis (RA) and joint destruction. METHODS: We measured…”
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Elevated IL-16 level is a non-genetic characteristic of patients with severe systemic lupus erythematosus by Lard, LR, Roep, BO, Huizinga, TWJ

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Functional regulatory immune responses against human cartilage glycoprotein-39 in health versus proinflammatory responses in rheumatoid arthritis by van Bilsen, JHM, van Dongen, H, Lard, LR, van der Voort, EIH, Elferink, DG, Bakker, AM, Miltenburg, AMM, Huizinga, TWJ, de Vries, RRP, Toes, REM

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