Search Results - "Larcher, Lise"

Clinical and Molecular Determinants of Clonal Evolution in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria by Gurnari, Carmelo, Pagliuca, Simona, Prata, Pedro Henrique, Galimard, Jacques-Emmanuel, Catto, Luiz Fernando B, Larcher, Lise, Sebert, Marie, Allain, Vincent, Patel, Bhumika J, Durmaz, Arda, Pinto, Andre L, Inacio, Mariana C B, Hernandez, Lucie, Dhedin, Nathalie, Caillat-Zucman, Sophie, Clappier, Emmanuelle, Sicre de Fontbrune, Flore, Voso, Maria Teresa, Visconte, Valeria, Peffault de Latour, Régis, Soulier, Jean, Calado, Rodrigo T, Socié, Gérard, Maciejewski, Jaroslaw P

“…Secondary myeloid neoplasms (sMNs) remain the most serious long-term complications in patients with aplastic anemia (AA) and paroxysmal nocturnal…”
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Prevalence of UBA1 mutations in MDS/CMML patients with systemic inflammatory and auto-immune disease by Zhao, Lin-Pierre, Schell, Berenice, Sébert, Marie, Kim, Rathana, Lemaire, Pierre, Boy, Maxime, Mathis, Stephanie, Larcher, Lise, Chauvel, Clémentine, Dhouaieb, Mohamed Bedis, Bisio, Valéria, Preudhomme, Claude, Marceau-Renaut, Alice, Itzykson, Raphaël, Mekinian, Arsène, Fain, Olivier, Toubert, Antoine, Fenaux, Pierre, Dulphy, Nicolas, Clappier, Emmanuelle, Adès, Lionel

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Low-dose non-steroidal anti-inflammatory drugs: a promising approach for the treatment of symptomatic bone marrow failure in Ghosal hematodiaphyseal dysplasia by Bordat, Jonathan, Suarez, Felipe, Cormier-Daire, Valérie, De Latour, Regis Peffault, Soulier, Jean, Meignin, Veronique, Doyard, Mathilde, Larcher, Lise, Vanderbecken, Stephane, De Fontbrune, Flore Sicre

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Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation by Boy, Maxime, Bisio, Valeria, Zhao, Lin-Pierre, Guidez, Fabien, Schell, Bérénice, Lereclus, Emilie, Henry, Guylaine, Villemonteix, Juliette, Rodrigues-Lima, Fernando, Gagne, Katia, Retiere, Christelle, Larcher, Lise, Kim, Rathana, Clappier, Emmanuelle, Sebert, Marie, Mekinian, Arsène, Fain, Olivier, Caignard, Anne, Espeli, Marion, Balabanian, Karl, Toubert, Antoine, Fenaux, Pierre, Ades, Lionel, Dulphy, Nicolas

“…Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders, representing high risk of progression to acute myeloid leukaemia, and frequently associated…”
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Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL by Passet, Marie, Kim, Rathana, Gachet, Stéphanie, Sigaux, François, Chaumeil, Julie, Galland, Ava, Sexton, Thomas, Quentin, Samuel, Hernandez, Lucie, Larcher, Lise, Bergugnat, Hugo, Ye, Tao, Karasu, Nezih, Caye, Aurélie, Heizmann, Beate, Duluc, Isabelle, Chevallier, Patrice, Rousselot, Philippe, Huguet, Françoise, Leguay, Thibaut, Hunault, Mathilde, Pflumio, Françoise, Freund, Jean-Noël, Lobry, Camille, Lhéritier, Véronique, Dombret, Hervé, Domon-Dell, Claire, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle

“…Oncogenic alterations underlying B-cell acute lymphoblastic leukemia (B-ALL) in adults remain incompletely elucidated. To uncover novel oncogenic drivers, we…”
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Orogenital Transmission of Neisseria meningitidis Causing Acute Urethritis in Men Who Have Sex with Men by Jannic, Arnaud, Mammeri, Hedi, Larcher, Lise, Descamps, Vincent, Tosini, William, Phung, Bao, Yazdanpanah, Yazdan, Bouscarat, Fabrice

“…Neisseria meningitidis sequence type 11 is an emerging cause of urethritis. We demonstrate by using whole-genome sequencing orogenital transmission of a N…”
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Somatic genetic alterations predict hematological progression in GATA2 deficiency by Largeaud, Laetitia, Collin, Matthew, Monselet, Nils, Vergez, Francois, Fregona, Vincent, Larcher, Lise, Hirsch, Pierre, Duployez, Nicolas, Bidet, Audrey, Luquet, Isabelle, Bustamante, Jacinta, Dufrechou, Stephanie, Prade, Nais, Nolla, Marie, Hamelle, Camille, Tavitian, Suzanne, Habib, Christophe, Meynier, Mateo, Bellanne-Chantelot, Christine, Donadieu, Jean, De Fontbrune, Flore Sicre, Fieschi, Claire, Ferster, Alina, Delhommeau, Francois, Delabesse, Eric, Pasquet, Marlene

“…Germline GATA2 mutations predispose to myeloid malignancies resulting from the progressive acquisition of additional somatic mutations. Here we describe…”
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Allogeneic transplantation in acute myelogenous leukemia: a comprehensive single institution's experience by Socie, Gerard, Galimard, Jacques-Emmanuel, Raffoux, Emmanuel, Itzykson, Raphael, Debureaux, Pierre Edouard, Michonneau, David, Lengliné, Etienne, Robin, Marie, De Fontbrune, Flore Sicre, Sébert, Marie, Xhaard, Aliénor, Kim, Rathana, Couprie, Anne, Dhedin, Nathalie, Dragani, Matteo, Lemaire, Pierre, Larcher, Lise, Clappier, Emmanuelle, Boissel, Nicolas, Soulier, Jean, Dombret, Hervé, Fenaux, Pierre, De Latour, Régis Peffault, Adès, Lionel

“…Since decades, debates on the role and timing of allogeneic transplantation HSCT in acute myelogenous leukemia (AML) persist. Time to transplant introduces an…”
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Variants in TCF20 in neurodevelopmental disability: description of 27 new patients and review of literature by Torti, Erin, Keren, Boris, Palmer, Elizabeth E., Zhu, Zehua, Afenjar, Alexandra, Anderson, Ilse. J., Andrews, Marisa V., Atkinson, Celia, Au, Margaret, Berry, Susan A., Bowling, Kevin M., Boyle, Jackie, Buratti, Julien, Cathey, Sara S., Charles, Perrine, Cogne, Benjamin, Courtin, Thomas, Escobar, Luis F., Finley, Sabra Ledare, Graham, John M., Grange, Dorothy K., Heron, Delphine, Hewson, Stacy, Hiatt, Susan M., Hibbs, Kathleen A., Jayakar, Parul, Kalsner, Louisa, Larcher, Lise, Lesca, Gaetan, Mark, Paul R., Miller, Kathryn, Nava, Caroline, Nizon, Mathilde, Pai, G. Shashidhar, Pappas, John, Parsons, Gretchen, Payne, Katelyn, Putoux, Audrey, Rabin, Rachel, Sabatier, Isabelle, Shinawi, Marwan, Shur, Natasha, Skinner, Steven A., Valence, Stephanie, Warren, Hannah, Whalen, Sandra, Crunk, Amy, Douglas, Ganka, Monaghan, Kristin G., Person, Richard E., Willaert, Rebecca, Solomon, Benjamin D., Juusola, Jane

“…To define the clinical characteristics of patients with variants in TCF20, we describe 27 patients, 26 of whom were identified via exome sequencing. We compare…”
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Hematopoietic differentiation at single-cell resolution in NPM1-mutated AML by Duchmann, Matthieu, Joudinaud, Romane, Boudry, Augustin, Pasanisi, Justine, Di Feo, Giuseppe, Kim, Rathana, Bucci, Maxime, Chauvel, Clémentine, Chat, Laureen, Larcher, Lise, Pacchiardi, Kim, Mathis, Stéphanie, Raffoux, Emmanuel, Adès, Lionel, Berthon, Céline, Clappier, Emmanuelle, Roumier, Christophe, Puissant, Alexandre, Preudhomme, Claude, Duployez, Nicolas, Itzykson, Raphaël

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Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes by Sevilla, Julián, Navarro, Susana, Rio, Paula, Sánchez-Domínguez, Rebeca, Zubicaray, Josune, Gálvez, Eva, Merino, Eva, Sebastián, Elena, Azqueta, Carmen, Casado, José A., Segovia, José C., Alberquilla, Omaira, Bogliolo, Massimo, Román-Rodríguez, Francisco J., Giménez, Yari, Larcher, Lise, Salgado, Rocío, Pujol, Roser M., Hladun, Raquel, Castillo, Ana, Soulier, Jean, Querol, Sergi, Fernández, Jesús, Schwartz, Jonathan, García de Andoín, Nagore, López, Ricardo, Catalá, Albert, Surralles, Jordi, Díaz-de-Heredia, Cristina, Bueren, Juan A.

“…Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this…”
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P315: TP53 ALTERATIONS AND MRD REFINE PROGNOSIS OF ADULT KMT2A‐REARRANGED B‐ALL by Kim, Rathana, Bergugnat, Hugo, Pasquier, Florence, Raffoux, Emmanuel, Larcher, Lise, Passet, Marie, Pastoret, Cedric, Nathalie, Grardel, Asnafi, Vahid, Delabesse, Eric, Caye‐Eude, Aurélie, Meyer, Claus, Masrschalek, Rolf, Thiebaut‐Bertrand, Anne, Balsat, Marie, Escoffre, Martine, Blum, Sabine, Baumann, Michael, Banos, Anne, Straetmans, Nicole, Pilar Gallego Hernanz, Maria, Chalandon, Yves, Graux, Carlos, Leguay, Thibaut, Hunault, Mathilde, Huguet, Françoise, Lhéritier, Véronique, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle

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Prognostic impact of DDX41 germline mutations in intensively treated acute myeloid leukemia patients: an ALFA-FILO study by Duployez, Nicolas, Largeaud, Laëtitia, Duchmann, Matthieu, Kim, Rathana, Rieunier, Julie, Lambert, Juliette, Bidet, Audrey, Larcher, Lise, Lemoine, Jean, Delhommeau, François, Hirsch, Pierre, Fenwarth, Laurène, Kosmider, Olivier, Decroocq, Justine, Bouvier, Anne, Le Bris, Yannick, Ochmann, Marlène, Santagostino, Alberto, Adès, Lionel, Fenaux, Pierre, Thomas, Xavier, Micol, Jean-Baptiste, Gardin, Claude, Itzykson, Raphael, Soulier, Jean, Clappier, Emmanuelle, Recher, Christian, Preudhomme, Claude, Pigneux, Arnaud, Dombret, Hervé, Delabesse, Eric, Sébert, Marie

“…DDX41 germline mutations (DDX41MutGL) are the most common genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia (AML). Recent reports…”
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Characteristics of Germline CHEK2 Mutated Patients in a Large Cohort of 2322 Myeloid Malignancies by Freiman, Lucie, Larcher, Lise, Tueur, Giulia, Vasquez, Nadia, Da Costa, Mélanie, Raffoux, Emmanuel, Ades, Lionel, Fenaux, Pierre, Soulier, Jean, Clappier, Emmanuelle, Itzykson, Raphael

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Germline CHEK2 mutations in patients with myeloid neoplasms by Freiman, Lucie, Larcher, Lise, Tueur, Giulia, Vasquez, Nadia, Da Costa, Mélanie, Duchmann, Matthieu, Raffoux, Emmanuel, Adès, Lionel, Fenaux, Pierre, Soulier, Jean, Duployez, Nicolas, Clappier, Emmanuelle, Sébert, Marie

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Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia by Sebert, Marie, Gachet, Stéphanie, Leblanc, Thierry, Rousseau, Alix, Bluteau, Olivier, Kim, Rathana, Ben Abdelali, Raouf, Sicre de Fontbrune, Flore, Maillard, Loïc, Fedronie, Carèle, Murigneux, Valentine, Bellenger, Léa, Naouar, Naira, Quentin, Samuel, Hernandez, Lucie, Vasquez, Nadia, Da Costa, Mélanie, Prata, Pedro H., Larcher, Lise, de Tersant, Marie, Duchmann, Matthieu, Raimbault, Anna, Trimoreau, Franck, Fenneteau, Odile, Cuccuini, Wendy, Gachard, Nathalie, Auger, Nathalie, Tueur, Giulia, Blanluet, Maud, Gazin, Claude, Souyri, Michèle, Langa Vives, Francina, Mendez-Bermudez, Aaron, Lapillonne, Hélène, Lengline, Etienne, Raffoux, Emmanuel, Fenaux, Pierre, Adès, Lionel, Forcade, Edouard, Jubert, Charlotte, Domenech, Carine, Strullu, Marion, Bruno, Bénédicte, Buchbinder, Nimrod, Thomas, Caroline, Petit, Arnaud, Leverger, Guy, Michel, Gérard, Cavazzana, Marina, Gluckman, Eliane, Bertrand, Yves, Boissel, Nicolas, Baruchel, André, Dalle, Jean-Hugues, Clappier, Emmanuelle, Gilson, Eric, Deriano, Ludovic, Chevret, Sylvie, Sigaux, François, Socié, Gérard, Stoppa-Lyonnet, Dominique, de Thé, Hugues, Antoniewski, Christophe, Bluteau, Dominique, Peffault de Latour, Régis, Soulier, Jean

“…Fanconi anemia (FA) patients experience chromosome instability, yielding hematopoietic stem/progenitor cell (HSPC) exhaustion and predisposition to…”
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A novel cancer risk prediction score for the natural course of FA patients with biallelic BRCA2/FANCD1 mutations by Radulovic, Ivana, Schündeln, Michael M, Müller, Lisa, Ptok, Johannes, Honisch, Ellen, Niederacher, Dieter, Wiek, Constanze, Scheckenbach, Kathrin, Leblanc, Thierry, Larcher, Lise, Soulier, Jean, Reinhardt, Dirk, Schaal, Heiner, Andreassen, Paul R, Hanenberg, Helmut

“…Abstract Biallelic germline mutations in BRCA2 occur in the Fanconi anemia (FA)-D1 subtype of the rare pediatric disorder, FA, characterized clinically by…”
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A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells by Berrada, Sara, Martínez-Balsalobre, Elena, Larcher, Lise, Azzoni, Violette, Vasquez, Nadia, Da Costa, Mélanie, Abel, Sébastien, Audoly, Gilles, Lee, Lara, Montersino, Camille, Castellano, Rémy, Combes, Sébastien, Gelot, Camille, Ceccaldi, Raphaël, Guervilly, Jean-Hugues, Soulier, Jean, Lachaud, Christophe

“…Abstract Fanconi anemia (FA) is a genetic disorder associated with developmental defects, bone marrow failure and cancer. The FA pathway is crucial for the…”
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3041 – THE ROLE OF CLONAL HEMATOPOIESIS IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA by Clappier, Emmanuelle, Kim, Rathana, Bergugnat, Hugo, Larcher, Lise, Duchmann, Matthieu, Passet, Marie, Gachet, Stéphanie, Lafage, Marina, Chevallier, Patrice, Hunault, Mathilde, Leguay, Thibaut, Huguet, Francoise, Lhéritier, Véronique, Dombret, Hervé, Soulier, Jean, Rousselot, Philippe, Boissel, Nicolas

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Genetic alterations and MRD refine risk assessment for KMT2A-rearranged B-cell precursor ALL in adults: a GRAALL study by Kim, Rathana, Bergugnat, Hugo, Pastoret, Cédric, Pasquier, Florence, Raffoux, Emmanuel, Larcher, Lise, Passet, Marie, Grardel, Nathalie, Delabesse, Eric, Kubetzko, Susanne, Caye-Eude, Aurélie, Meyer, Claus, Marschalek, Rolf, Lafage-Pochitaloff, Marine, Thiebaut-Bertrand, Anne, Balsat, Marie, Escoffre-Barbe, Martine, Blum, Sabine, Baumann, Michael, Banos, Anne, Straetmans, Nicole, Gallego-Hernanz, Maria-Pilar, Chalandon, Yves, Graux, Carlos, Soulier, Jean, Leguay, Thibaut, Hunault, Mathilde, Huguet, Françoise, Lhéritier, Véronique, Dombret, Hervé, Boissel, Nicolas, Clappier, Emmanuelle

“…KMT2A-rearranged (KMT2A-r) B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is widely recognized as a high-risk leukemia in both children and adults…”
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