Search Results - "Larcher, Leon M"

Progress, opportunity, and perspective on exosome isolation - efforts for efficient exosome-based theranostics by Yang, Dongbin, Zhang, Weihong, Zhang, Huanyun, Zhang, Fengqiu, Chen, Lanmei, Ma, Lixia, Larcher, Leon M, Chen, Suxiang, Liu, Nan, Zhao, Qingxia, Tran, Phuong H L, Chen, Changying, Veedu, Rakesh N, Wang, Tao

“…Exosomes are small extracellular vesicles with diameters of 30-150 nm. In both physiological and pathological conditions, nearly all types of cells can release…”
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Systematic Screening of Commonly Used Commercial Transfection Reagents towards Efficient Transfection of Single-Stranded Oligonucleotides by Wang, Tao, Larcher, Leon M, Ma, Lixia, Veedu, Rakesh N

“…Non-viral vector-mediated transfection is a core technique for in vitro screening of oligonucleotides. Despite the growing interests in the development of…”
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Adverse reactions of targeted therapy in cancer patients: a retrospective study of hospital medical data in China by Du, Ruofei, Wang, Xin, Ma, Lixia, Larcher, Leon M, Tang, Han, Zhou, Huiyue, Chen, Changying, Wang, Tao

“…The adverse reactions (ADRs) of targeted therapy were closely associated with treatment response, clinical outcome, quality of life (QoL) of patients with…”
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Health-related quality of life and associated factors in patients with myocardial infarction after returning to work: a cross-sectional study by Du, Ruofei, Wang, Panpan, Ma, Lixia, Larcher, Leon M, Wang, Tao, Chen, Changying

“…Abstract Background Return to work following myocardial infarction (MI) represents an important indicator of recovery. However, MI can cause patients to feel…”
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Development of Novel antimiRzymes for Targeted Inhibition of miR-21 Expression in Solid Cancer Cells by Larcher, Leon M, Wang, Tao, Veedu, Rakesh N

“…MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the regulation of gene expression. Previous reports showed an over-expression of miRNA-21…”
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Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro by Flynn, Loren L, Li, Ruohan, Pitout, Ianthe L, Aung-Htut, May T, Larcher, Leon M, Cooper, Jack A L, Greer, Kane L, Hubbard, Alysia, Griffiths, Lisa, Bond, Charles S, Wilton, Steve D, Fox, Archa H, Fletcher, Sue

“…Oligonucleotides and nucleic acid analogues that alter gene expression are now showing therapeutic promise in human disease. Whilst the modification of…”
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Three decades of nucleic acid aptamer technologies: Lessons learned, progress and opportunities on aptamer development by Wang, Tao, Chen, Changying, Larcher, Leon M., Barrero, Roberto A., Veedu, Rakesh N.

“…Aptamers are short single-stranded nucleic acid sequences capable of binding to target molecules in a way similar to antibodies. Due to various advantages such…”
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The health-related quality of life of lung cancer patients with EGFR-TKI-related skin adverse drug reactions and its relationship with coping style and self-management by Du, Ruofei, Wang, Xin, Zhou, Huiyue, Ma, Lixia, Larcher, Leon M., Chen, Changying, Wang, Tao

“…Purpose The status and associated factors of the health-related quality of life of non-small-cell lung cancer (NSCLC) patients under targeted anti-cancer…”
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Therapeutically Significant MicroRNAs in Primary and Metastatic Brain Malignancies by Balachandran, Akilandeswari A., Larcher, Leon M., Chen, Suxiang, Veedu, Rakesh N.

“…Brain cancer is one among the rare cancers with high mortality rate that affects both children and adults. The most aggressive form of primary brain tumor is…”
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