Search Results - "Lara‐Ramírez, Edgar E."

Circulating miR‐146a, miR‐34a and miR‐375 in type 2 diabetes patients, pre‐diabetic and normal‐glycaemic individuals in relation to β‐cell function, insulin resistance and metabolic parameters by García‐Jacobo, Rocío E., Uresti‐Rivera, Edith E., Portales‐Pérez, Diana P., González‐Amaro, Roberto, Lara‐Ramírez, Edgar E., Enciso‐Moreno, José A., García‐Hernández, Mariana H.

“…The pathogenesis of type 2 diabetes (T2D) is associated with a progressive loss of pancreatic β‐cell mass. It is known that miR‐146a, miR‐34a, and miR‐375 are…”
Get full text

Virtual Screening of FDA-Approved Drugs against Triose Phosphate Isomerase from Entamoeba histolytica and Giardia lamblia Identifies Inhibitors of Their Trophozoite Growth Phase by Juárez-Saldivar, Alfredo, Barbosa-Cabrera, Elizabeth, Lara-Ramírez, Edgar E., Paz-González, Alma D., Martínez-Vázquez, Ana V., Bocanegra-García, Virgilio, Palos, Isidro, Campillo, Nuria E., Rivera, Gildardo

“…Infectious diseases caused by intestinal protozoan, such as Entamoeba histolytica (E. histolytica) and Giardia lamblia (G. lamblia) are a worldwide public…”
Get full text

Current Strategy for Targeting Metallo-β-Lactamase with Metal-Ion-Binding Inhibitors by Ortega-Balleza, Jessica L, Vázquez-Jiménez, Lenci K, Ortiz-Pérez, Eyra, Avalos-Navarro, Guadalupe, Paz-González, Alma D, Lara-Ramírez, Edgar E, Rivera, Gildardo

“…Currently, antimicrobial resistance (AMR) is a serious health problem in the world, mainly because of the rapid spread of multidrug-resistant (MDR) bacteria…”
Get full text

Genomic epidemiology analysis of drug-resistant Mycobacterium tuberculosis distributed in Mexico by Mejía-Ponce, Paulina M, Ramos-González, Elsy J, Ramos-García, Axel A, Lara-Ramírez, Edgar E, Soriano-Herrera, Alma R, Medellín-Luna, Mitzy F, Valdez-Salazar, Fernando, Castro-Garay, Claudia Y, Núñez-Contreras, José J, De Donato-Capote, Marcos, Sharma, Ashutosh, Castañeda-Delgado, Julio E, Zenteno-Cuevas, Roberto, Enciso-Moreno, Jose Antonio, Licona-Cassani, Cuauhtémoc

“…Genomics has significantly revolutionized pathogen surveillance, particularly in epidemiological studies, the detection of drug-resistant strains, and disease…”
Get full text

GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the synovium by Fernández‐Ruiz, Julio Cesar, Ochoa‐González, Fátima de Lourdes, Zapata‐Zúñiga, Martín, Mondragon‐Marín, Eduardo, Lara‐Ramírez, Edgar E., Ruíz‐Carrillo, Jose Luis, DelaCruz‐Flores, Paola Amayrani, Layseca‐Espinosa, Esther, Enciso‐Moreno, José Antonio, Castañeda‐Delgado, Julio Enrique

“…The rheumatoid arthritis (RA) inflammatory process occurs in the joints where immune cells are attracted into the synovium to promote remodeling and tissue…”
Get full text

Lipid Metabolism Alterations in a Rat Model of Chronic and Intergenerational Exposure to Arsenic by Rivas-Santiago, Bruno, Lopez, Jesús Adrián, Cervantes-Villagrana, Alberto R., López-Hernández, Yamilé, Vázquez, Edgar, Lara-Ramírez, Edgar E., Lazalde, Blanca, Ruiz Cardona, Alonso, Murgu, Michael, Zarazua, Sergio, González-Curiel, Irma, Rivas-Santiago, Cesar, Castañeda-Delgado, Julio Enrique

“…Chronic exposure to arsenic (As), whether directly through the consumption of contaminated drinking water or indirectly through the daily intake of…”
Get full text

The analysis on the human protein domain targets and host-like interacting motifs for the MERS-CoV and SARS-CoV/CoV-2 infers the molecular mimicry of coronavirus by Martínez, Yamelie A, Guo, Xianwu, Portales-Pérez, Diana P, Rivera, Gildardo, Castañeda-Delgado, Julio E, García-Pérez, Carlos A, Enciso-Moreno, José A, Lara-Ramírez, Edgar E

“…The MERS-CoV, SARS-CoV, and SARS-CoV-2 are highly pathogenic viruses that can cause severe pneumonic diseases in humans. Unfortunately, there is a…”
Get full text

Polyamines Influence Mouse Sperm Channels Activity by Rodríguez-Páez, Lorena, Aguirre-Alvarado, Charmina, Oviedo, Norma, Alcántara-Farfán, Verónica, Lara-Ramírez, Edgar E, Jimenez-Gutierrez, Guadalupe Elizabeth, Cordero-Martínez, Joaquín

“…Polyamines are ubiquitous polycationic compounds that are highly charged at physiological pH. While passing through the epididymis, sperm lose their capacity…”
Get full text

Structure-Based Virtual Screening and In Vitro Evaluation of New Trypanosoma cruzi Cruzain Inhibitors by Herrera-Mayorga, Verónica, Lara-Ramírez, Edgar E, Chacón-Vargas, Karla F, Aguirre-Alvarado, Charmina, Rodríguez-Páez, Lorena, Alcántara-Farfán, Verónica, Cordero-Martínez, Joaquín, Nogueda-Torres, Benjamín, Reyes-Espinosa, Francisco, Bocanegra-García, Virgilio, Rivera, Gildardo

“…Chagas disease (CD), or American trypanosomiasis, causes more than 10,000 deaths per year in the Americas. Current medical therapy for CD has low efficacy in…”
Get full text

Transcriptional signature associated with early rheumatoid arthritis and healthy individuals at high risk to develop the disease by Macías-Segura, N, Castañeda-Delgado, J E, Bastian, Y, Santiago-Algarra, D, Castillo-Ortiz, J D, Alemán-Navarro, A L, Jaime-Sánchez, E, Gomez-Moreno, M, Saucedo-Toral, C A, Lara-Ramírez, Edgar E, Zapata-Zuñiga, M, Enciso-Moreno, L, González-Amaro, R, Ramos-Remus, C, Enciso-Moreno, J A

“…Little is known regarding the mechanisms underlying the loss of tolerance in the early and preclinical stages of autoimmune diseases. The aim of this work was…”
Get full text

Biological Evaluations and Computer-Aided Approaches of Janus Kinases 2 and 3 Inhibitors for Cancer Treatment: A Review by Vázquez-Jiménez, Lenci K, Rivera, Gildardo, Juárez-Saldivar, Alfredo, Ortega-Balleza, Jessica L, Ortiz-Pérez, Eyra, Jaime-Sánchez, Elena, Paz-González, Alma, Lara-Ramírez, Edgar E

“…Cancer remains one of the leading diseases of mortality worldwide. Janus kinases 2/3 (JAK2/3) have been considered a drug target for the development of drugs…”
Get full text

Virtual Screening of Benzimidazole Derivatives as Potential Triose Phosphate Isomerase Inhibitors with Biological Activity against Leishmania mexicana by Vázquez-Jiménez, Lenci K, Juárez-Saldivar, Alfredo, Chan-Bacab, Manuel J, Delgado-Maldonado, Timoteo, González-Morales, Luis D, Palos, Isidro, Ortiz-Pérez, Eyra, Lara-Ramírez, Edgar E, Ramírez-Moreno, Esther, Rivera, Gildardo

“…( ) is a causal agent of cutaneous leishmaniasis (CL), a " ", for which the search for new drugs is a priority. Benzimidazole is a scaffold used to develop…”
Get full text

Triose Phosphate Isomerase Structure-Based Virtual Screening and In Vitro Biological Activity of Natural Products as Leishmania mexicana Inhibitors by González-Morales, Luis D., Moreno-Rodríguez, Adriana, Vázquez-Jiménez, Lenci K., Delgado-Maldonado, Timoteo, Juárez-Saldivar, Alfredo, Ortiz-Pérez, Eyra, Paz-Gonzalez, Alma D., Lara-Ramírez, Edgar E., Yépez-Mulia, Lilian, Meza, Patricia, Rivera, Gildardo

“…Cutaneous leishmaniasis (CL) is a public health problem affecting more than 98 countries worldwide. No vaccine is available to prevent the disease, and…”
Get full text

Ligand- and Structure-Based Virtual Screening Identifies New Inhibitors of the Interaction of the SARS-CoV-2 Spike Protein with the ACE2 Host Receptor by Delgado-Maldonado, Timoteo, González-González, Alonzo, Moreno-Rodríguez, Adriana, Bocanegra-García, Virgilio, Martinez-Vazquez, Ana Verónica, de Luna-Santillana, Erick de Jesús, Pujadas, Gerard, Rojas-Verde, Guadalupe, Lara-Ramírez, Edgar E, Rivera, Gildardo

“…The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a fast-spreading viral pathogen and poses a serious threat to human health. New SARS-CoV-2…”
Get full text

Bioinformatic prediction of the molecular links between Alzheimer's disease and diabetes mellitus by Castillo-Velázquez, Ricardo, Martínez-Morales, Flavio, Castañeda-Delgado, Julio E, García-Hernández, Mariana H, Herrera-Mayorga, Verónica, Paredes-Sánchez, Francisco A, Rivera, Gildardo, Rivas-Santiago, Bruno, Lara-Ramírez, Edgar E

“…Alzheimer's disease (AD) and type 2 diabetes mellitus (DM2) are chronic degenerative diseases with complex molecular processes that are potentially…”
Get full text

Anti- Mycobacterium tuberculosis Activity of Esters of Quinoxaline 1,4-Di- N -Oxide by Palos, Isidro, Luna-Herrera, Julieta, Lara-Ramírez, Edgar E, Loera-Piedra, Alejandra, Fernández-Ramírez, Emanuel, Aguilera-Arreola, Ma Guadalupe, Paz-González, Alma D, Monge, Antonio, Wan, Baojie, Franzblau, Scott, Rivera, Gildardo

“…Tuberculosis continues to be a public health problem in the world, and drug resistance has been a major obstacle in its treatment. Quinoxaline 1,4-di- -oxide…”
Get full text

Time series analysis of onchocerciasis data from Mexico: a trend towards elimination by Lara-Ramírez, Edgar E, Rodríguez-Pérez, Mario A, Pérez-Rodríguez, Miguel A, Adeleke, Monsuru A, Orozco-Algarra, María E, Arrendondo-Jiménez, Juan I, Guo, Xianwu

“…In Latin America, there are 13 geographically isolated endemic foci distributed among Mexico, Guatemala, Colombia, Venezuela, Brazil and Ecuador. The…”
Get full text

Potential molecular patterns for tuberculosis susceptibility in diabetic patients with poor glycaemic control: a pilot study by Jaime-Sánchez, Elena, Lara-Ramírez, Edgar E., López-Ramos, Juan Ernesto, Ramos-González, Elsy Janeth, Cisneros-Méndez, Ana Laura, Oropeza-Valdez, Juan José, Zenteno-Cuevas, Roberto, Martínez-Aguilar, Gerardo, Bastian, Yadira, Castañeda-Delgado, Julio Enrique, Serrano, Carmen Judith, Enciso-Moreno, José Antonio

“…Type 2 diabetes (DM2) is an increasingly prevalent disease that challenges tuberculosis (TB) control strategies worldwide. It is significant that DM2 patients…”
Get full text

Transcriptome Analysis Identifies Oxidative Stress Injury Biomarkers for Diabetic Nephropathy by Oropeza-Valdez, Juan José, Hernandez, José de la Cruz Moreira, Jaime-Sánchez, Elena, López-Ramos, Ernesto, Lara-Ramírez, Edgar E., Hernández, Yamilé López, Castañeda-Delgado, Julio Enrique, Moreno, José Antonio Enciso

“…The early diagnosis of diabetic nephropathy (DN) is essential for improving the prognosis and effectively manage patients affected with this disease. The…”
Get full text

Detection of Inherent Homologous Recombination Between Repeat Sequences in H. pylori 26695 by the PCR-Based Method by Fu, Yajuan, Zepeda-Gurrola, Reyna Cristina, Aguilar-Gutiérrez, Germán Rubén, Lara-Ramírez, Edgar E, De Luna-Santillana, Erick J, Rodríguez-Luna, Isabel Cristina, Sánchez-Varela, Alejandro, Carreño-López, Ricardo, Moreno-Medina, Víctor Ricardo, Rodríguez-Pérez, Mario A, López-Vidal, Yolanda, Guo, Xianwu

“…Helicobacter pylori infects more than half of the world’s population, making it the most widespread infection of bacteria. It has high genetic diversity and…”
Get full text