Search Results - "Lara, Joshua"
-
1
Proteasome 26S subunit, non-ATPases 1 (PSMD1) and 3 (PSMD3), play an oncogenic role in chronic myeloid leukemia by stabilizing nuclear factor-kappa B
Published in Oncogene (15-04-2021)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 have revolutionized therapy for chronic myeloid leukemia (CML), paving the way for clinical development in…”
Get full text
Journal Article -
2
Validation of three viable-cell counting methods: Manual, semi-automated, and automated
Published in Biotechnology reports (Amsterdam, Netherlands) (01-09-2015)“…[Display omitted] A viable cell count is essential to evaluate the kinetics of cell growth. Since the hemocytometer was first used for counting blood cells,…”
Get full text
Journal Article -
3
Ethnic and border differences on blood cancer presentation and outcomes: A Texas population‐based study
Published in Cancer (01-04-2021)“…Background The Texas/Chihuahua (US/Mexico) border is a medically underserved region with many reported barriers for health care access. Although Hispanic…”
Get full text
Journal Article -
4
19S Proteasome Subunits as Oncogenes and Prognostic Biomarkers in FLT3-Mutated Acute Myeloid Leukemia (AML)
Published in International journal of molecular sciences (23-11-2022)“…26S proteasome non-ATPase subunits 1 (PSMD1) and 3 (PSMD3) were recently identified as prognostic biomarkers and potential therapeutic targets in chronic…”
Get full text
Journal Article -
5
A synthetic peptide from Trypanosoma cruzi mucin-like associated surface protein as candidate for a vaccine against Chagas disease
Published in Vaccine (12-06-2014)“…Highlights • We report a peptide-based vaccine candidate for Chagas disease. • Use of immunoinformatics for selection of an immunogenic peptide. • Peptide…”
Get full text
Journal Article -
6
26S Proteasome Non-ATPase Regulatory Subunits 1 (PSMD1) and 3 (PSMD3) as Putative Targets for Cancer Prognosis and Therapy
Published in Cells (Basel, Switzerland) (11-09-2021)“…Ever since the ubiquitin proteasome system was characterized, efforts have been made to manipulate its function to abrogate the progression of cancer. As a…”
Get full text
Journal Article -
7
Clinical predictors of survival in young patients with small cell lung cancer: Results from the California Cancer Registry
Published in Lung cancer (Amsterdam, Netherlands) (01-10-2017)“…•One of the largest registry studies of younger patients with SCLC ever reported.•Serves as a more contemporary foundational reference for future research in…”
Get full text
Journal Article -
8
Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism
Published in Clinical and translational medicine (01-12-2022)“…Tyrosine kinase inhibitors (TKIs) targeting BCR::ABL1 have turned chronic myeloid leukaemia (CML) from a fatal disease into a manageable condition for most…”
Get full text
Journal Article -
9
19S Proteasome Subunits As Oncogenes and Prognostic Biomarkers in FLT3-Mutated Acute Myeloid Leukemia (AML)
Published in Blood (15-11-2022)Get full text
Journal Article -
10
Determinants of Survival for Adolescents and Young Adults with Urothelial Bladder Cancer: Results from the California Cancer Registry
Published in The Journal of urology (01-11-2016)“…Purpose Bladder cancer is a common malignancy often diagnosed in older adults. Previous studies have reported racial/ethnic disparities in bladder cancer…”
Get full text
Journal Article -
11
Abstract 647: NF-kB associates with tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 are effective at eliminating most BCR-ABL1+ cells in chronic myeloid leukemia (CML), but do not target CML…”
Get full text
Journal Article -
12
Abstract 4343: Retrospective study of incidence and survival for patients with hematological malignancies residing at the U.S./Mexico border
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Introduction: Hispanics represent the largest minority group in the United States (U.S.), with 57.5 million individuals. The majority of Hispanics in the U.S…”
Get full text
Journal Article -
13
Abstract 648: Role of G0S2 in chronic myeloid leukemia and TKI resistance
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 have turned chronic myeloid leukemia (CML) from a fatal to a chronic disease. However, resistance is a…”
Get full text
Journal Article -
14
Proteasome 26S subunit, non-ATPases 1 , play an oncogenic role in chronic myeloid leukemia by stabilizing nuclear factor-kappa B
Published in Oncogene (15-04-2021)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 have revolutionized therapy for chronic myeloid leukemia (CML), paving the way for clinical development in…”
Get full text
Journal Article -
15
NF-κB-Dependent Activation of the Proteasome Components, PSMD1 and PSMD3, As a Mechanism of Resistance to Imatinib
Published in Blood (13-11-2019)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 are remarkably effective therapies in chronic myeloid leukemia (CML). Despite clinical success, TKIs do…”
Get full text
Journal Article -
16
Retrospective Study of Incidence and Survival for Patients with Hematologic Malignancies Residing at the U.S./Mexico Border
Published in Blood (13-11-2019)“…Introduction: Hispanics represent the largest minority group in the United States (U.S.), with 57.5 million individuals (18% of the population). Most U.S…”
Get full text
Journal Article -
17
Determinants of survival in adolescents and young adults with urothelial cancer: Results from the California Cancer Registry
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
Get full text
Journal Article -
18
A synthetic peptide fromTrypanosoma cruzimucin-like associated surface protein as candidate for a vaccine against Chagas disease
Published in Vaccine (12-06-2014)“…Chagas disease, caused byTrypanosoma cruzi, is responsible for producing significant morbidity and mortality throughout Latin America. The disease has recently…”
Get full text
Journal Article -
19
Phylogeography of the natal puddle frog Phrynobatrachus natalensis (Anura: Phrynobatrachidae) in Sub-Saharan Africa
Published 01-01-2016“…The Family Phrynobatrachidae (Laurent, 1941) has one genus (Phrynobatrachus, Günther, 1862) containing 89 species. Commonly known as puddle frogs, they…”
Get full text
Dissertation