Search Results - "Lara, J. Manuel Tunon"

Tryptase‐stimulated human airway smooth muscle cells induce cytokine synthesis and mast cell Chemotaxis by Berger, Patrick, Girodet, Pierre-Olivier, Begueret, Hugues, Ousova, Olga, Perng, Diahn-Warng, Marthan, Roger, Walls, Andrew F., Lara, J. Manuel Tunon

“…ABSTRACT Asthmatic patients have higher numbers of mast cells in the smooth muscle layer of airways than normal subjects. Human airway smooth muscle cells…”
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Sublingual-swallow immunotherapy with standardized 3-grass pollen extract: a double-blind, placebo-controlled study by de Blay, Frédéric, MD, Barnig, Cindy, MD, Kanny, Gisèle, MD, PhD, Purohit, Ashok, MD, Leynadier, Francisque, MD, de Lara, J Manuel Tunon, MD, PhD, Chabane, Habib, MD, PhD, Guérin, Laurence, PhD

“…Background Sublingual immunotherapy (SLIT) is accepted as a safe and effective route for the treatment of grass pollen allergy, but clarification of its…”
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Fraktalkine Produced by Airway Smooth Muscle Cells Contributes to Mast Cell Recruitment in Asthma by El-Shazly, Amr, Berger, Patrick, Girodet, Pierre-Olivier, Ousova, Olga, Fayon, Michael, Vernejoux, Jean-Marc, Marthan, Roger, Tunon-de-Lara, J. Manuel

“…Human airway smooth muscle cells (HASMC) secrete fractalkine (FKN), a chemokine the concentration of which is increased in asthmatic patients. HASMC also…”
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Effects of Bronchial Obstruction on Lower Esophageal Sphincter Motility and Gastroesophageal Reflux in Patients with Asthma by Zerbib, Frank, Guisset, Olivier, Lamouliatte, Herve, Quinton, Andre, Galmiche, Jean Paul, Tunon-de-Lara, J. Manuel

“…The relationship between gastroesophageal reflux and asthma remains unclear. The aim of this study was to analyze the effect of bronchial obstruction on lower…”
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RNA Interference Decreases PAR-2 Expression and Function in Human Airway Smooth Muscle Cells by Trian, Thomas, Girodet, Pierre-Olivier, Ousova, Olga, Marthan, Roger, Tunon-de-Lara, J. Manuel, Berger, Patrick

“…Asthma is characterized by bronchial inflammation and hyperresponsiveness that involves mast cell tryptase and potentially its specific receptor protease…”
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Structure and function of small airways in smokers: relationship between air trapping at CT and airway inflammation by Berger, Patrick, Laurent, Francois, Begueret, Hugues, Perot, Vincent, Rouiller, Rozen, Raherison, Chantal, Molimard, Mathieu, Marthan, Roger, Tunon-de-Lara, J Manuel

“…To use quantitative computed tomography (CT) to compare lung attenuation with both inflammatory infiltration and in vitro reactivity of peripheral airways in…”
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Mast cell myositis: a new feature of allergic asthma? by Berger, P., Girodet, P.‐O., Manuel Tunon‐de‐Lara, J.

“…There is some evidence that, in asthma, mast cells infiltrate the airway smooth muscle layer and, as a consequence, alter the functional and structural…”
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Signal Transduction in Smooth Muscle: Selected Contribution: Tryptase-induced PAR-2-mediated Ca2+ signaling in human airway smooth muscle cells by Berger, Patrick, Tunon-De-Lara, J. Manuel, Savineau, Jean-Pierre, Marthan, Roger

“…Laboratoire de Physiologie Cellulaire Respiratoire, Inserm E9937, Université Bordeaux 2, 33076 Bordeaux, France Tryptase, the major mast cell product, is…”
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Chymase-positive mast cells: a double-edged sword in asthma? by Tunon-de-Lara, J Manuel, Berger, Patrick, Marthan, Roger

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Selected contribution: tryptase-induced PAR-2-mediated Ca(2+) signaling in human airway smooth muscle cells by Berger, P, Tunon-De-Lara, J M, Savineau, J P, Marthan, R

“…Tryptase, the major mast cell product, is considered to play an important role in airway inflammation and hyperresponsiveness. Tryptase produces different,…”
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Tryptase stimulates TGF-β1 synthesis and secretion, and the release of mast cell chemotactic activity from human airway smooth muscle cells by Berger, Patrick, Girodet, Pierre O, Marthan, Roger, Walls, Andrew F, de Lara, J Manuel Tunon

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Tryptase stimulates TGF-[beta]1 synthesis and secretion, and the release of mast cell chemotactic activity from human airway smooth muscle cells by Berger, Patrick, Girodet, Pierre O, Marthan, Roger, Walls, Andrew F, de Lara, J Manuel Tunon

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Editorial: Mast cell myositis: a new feature of allergic asthma? by Berger, P, P.-O. Girodet, Tunon-de-Lara, J Manuel

“…There is some evidence that, in asthma, mast cells infiltrate the airway smooth muscle layer and, as a consequence, alter the functional and structural…”
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Effects of bronchial obstruction on lower esophageal sphinecter motility and gastro-esophageal reflux in asthma by Zerbib, Frank, Guisset, Olivier, Lamouliatte, Herve, Quinton, Andre, Galmiche, Jean Paul, Lara, J Manuel Tunon de

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Chymase-positive Mast Cells: A Double-Edged Sword in Asthma?/From the Authors by Tunon-de-Lara, J Manuel, Berger, Patrick, Marthan, Roger, Balzar, Silvana, Wenzel, Sally E

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IgE-dependent expression of mRNA for IL-4 and IL-5 in human lung mast cells by Okayama, Y, Petit-Frere, C, Kassel, O, Semper, A, Quint, D, Tunon-de-Lara, MJ, Bradding, P, Holgate, ST, Church, MK

“…By using the reverse transcriptase (RT)-PCR and in situ hybridization we have studied the expression of mRNA for IL-5 and IL-4 in human lung mast cells induced…”
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Selected Contribution: Tryptase-induced PAR-2-mediated Ca 2+ signaling in human airway smooth muscle cells by Berger, Patrick, Tunon-De-Lara, J. Manuel, Savineau, Jean-Pierre, Marthan, Roger

“…Tryptase, the major mast cell product, is considered to play an important role in airway inflammation and hyperresponsiveness. Tryptase produces different,…”
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Immunoglobulin E-induced passive sensitization of human airways: An immunohistochemical study by BERGER, P, WALLS, A. F, MARTHAN, R, TUNON-DE-LARA, J. M

“…In vivo, IgE production is related to bronchial hyperresponsiveness and, in vitro, passive sensitization of human airways with asthmatic serum containing a…”
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Sensitization decreases relaxation in human isolated airways by Villanove, X, Marthan, R, Tunon de Lara, J M, Johnson, P R, Savineau, J P, McKay, K O, Alouan, L A, Armour, C L, Black, J L

“…Passively sensitized human isolated airways provide an opportunity to study some aspects of bronchial hyperresponsiveness in vitro. Since it has been suggested…”
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ACE inhibitors and anaphylactoid reactions during venom immunotherapy by Tunon-de-Lara, J M, Villanueva, P, Marcos, M, Taytard, A

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