Search Results - "Lapresa, Rebeca"

Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice by Burmistrova, Olga, Olias-Arjona, Ana, Lapresa, Rebeca, Jimenez-Blasco, Daniel, Eremeeva, Tatiana, Shishov, Dmitry, Romanov, Sergei, Zakurdaeva, Kristina, Almeida, Angeles, Fedichev, Peter O., Bolaños, Juan P.

“…The glycolytic rate in neurons is low in order to allow glucose to be metabolized through the pentose-phosphate pathway (PPP), which regenerates NADPH to…”
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APC/C-Cdh1-targeted substrates as potential therapies for Alzheimer's disease by Lapresa, Rebeca, Agulla, Jesus, Bolaños, Juan P, Almeida, Angeles

“…Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and the main cause of dementia in the elderly. The disease has a high impact on…”
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Amyloid-β Induces Cdh1-Mediated Rock2 Stabilization Causing Neurodegeneration by Lapresa, Rebeca, Agulla, Jesus, Gonzalez-Guerrero, Sonia, Bolaños, Juan P, Almeida, Angeles

“…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, which is causally related to the accumulation of…”
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AMYLOID-BETA INDUCES P53 STABILIZATION TRIGGERING NEUROINFLAMMATION by González-Guerrero, Sonia, Lapresa, Rebeca, Agulla, Jesus, Parra, Ángeles Almeida

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A Missense Variant in TP53 Could Be a Genetic Biomarker Associated with Bone Tissue Alterations by Usategui-Martín, Ricardo, Galindo-Cabello, Nadia, Pastor-Idoate, Salvador, Fernández-Gómez, José María, Del Real, Álvaro, Ferreño, Diego, Lapresa, Rebeca, Martín-Rodriguez, Francisco, Riancho, José A, Almeida, Ángeles, Pérez-Castrillón, José Luis

“…Metabolic bone diseases cover a broad spectrum of disorders that share alterations in bone metabolism that lead to a defective skeleton, which is associated…”
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Alleviation of cisplatin-induced neuropathic pain, neuronal apoptosis, and systemic inflammation in mice by rapamycin by Alotaibi, Moureq, Al-Aqil, Faten, Alqahtani, Faleh, Alanazi, Miteb, Nadeem, Ahmed, Ahmad, Sheikh F., Lapresa, Rebeca, Alharbi, Metab, Alshammari, Abdulrahman, Alotaibi, Muteb, Saleh, Tareq, Alrowis, Raed

“…Platinum-based chemotherapeutic treatment of cancer patients is associated with debilitating adverse effects. Several adverse effects have been well…”
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Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization by Lapresa, Rebeca, Agulla, Jesús, Sánchez-Morán, Irene, Zamarreño, Rubén, Prieto, Estefanía, Bolaños, Juan P., Almeida, Angeles

“…Neurodegeneration in selective brain areas underlies the pathology of Alzheimer's disease (AD). Although oligomeric amyloid-β (Aβ) plays a central role in the…”
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Impact of Fatty Acids on Astrocytic Bioenergetics by Morant-Ferrando, Brenda, Jimenez-Blasco, Daniel, Alonso-Batan, Paula, Agulla, Jesús, Garcia-Rodriguez, Dario, Yunta-Sanchez, Sara, Lapresa, Rebeca, Fernandez, Emilio, Carmeliet, Peter, Almeida, Angeles, Garcia-Macia, Marina, Bolaños, Juan P.

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Mitochondrial sodium/calcium exchanger NCLX regulates glycolysis in astrocytes, impacting on cognitive performance by Cabral‐Costa, João Victor, Vicente‐Gutiérrez, Carlos, Agulla, Jesús, Lapresa, Rebeca, Elrod, John W., Almeida, Ángeles, Bolaños, Juan P., Kowaltowski, Alicia J.

“…Intracellular Ca2+ concentrations are strictly controlled by plasma membrane transporters, the endoplasmic reticulum, and mitochondria, in which Ca2+ uptake is…”
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A Missense Variant in ITP53/I Could Be a Genetic Biomarker Associated with Bone Tissue Alterations by Usategui-Martín, Ricardo, Galindo-Cabello, Nadia, Pastor-Idoate, Salvador, Fernández-Gómez, José María, del Real, Álvaro, Ferreño, Diego, Lapresa, Rebeca, Martín-Rodriguez, Francisco, Riancho, José A, Almeida, Ángeles, Pérez-Castrillón, José Luis

“…Metabolic bone diseases cover a broad spectrum of disorders that share alterations in bone metabolism that lead to a defective skeleton, which is associated…”
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Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition by Morant-Ferrando, Brenda, Jimenez-Blasco, Daniel, Alonso-Batan, Paula, Agulla, Jesús, Lapresa, Rebeca, Garcia-Rodriguez, Dario, Yunta-Sanchez, Sara, Lopez-Fabuel, Irene, Fernandez, Emilio, Carmeliet, Peter, Almeida, Angeles, Garcia-Macia, Marina, Bolaños, Juan P.

“…Having direct access to brain vasculature, astrocytes can take up available blood nutrients and metabolize them to fulfil their own energy needs and deliver…”
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Inflammation status after retinal detachment could be modulate by TP53 gene by Galindo‐Cabello, Nadia, Pérez‐Prieto, Paula, Fernández‐Fernández, Julio, López‐García, Antonio, García‐Vázquez, Carmen, Rodríguez‐Cabello, José, Lapresa, Rebeca, Almeida, Angeles, Pastor‐Idoate, Salvador, Usategui‐Martin, Ricardo

“…Aims/Purpose: The TP53 Arg72Pro polymorphism has been linked to the risk of proliferative vitreoretinopathy (PVR) and may alter the functional prognosis of…”
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Weak neuronal glycolysis sustains cognition and organismal fitness by Jimenez-Blasco, Daniel, Agulla, Jesús, Lapresa, Rebeca, Garcia-Macia, Marina, Bobo-Jimenez, Veronica, Garcia-Rodriguez, Dario, Manjarres-Raza, Israel, Fernandez, Emilio, Jeanson, Yannick, Khoury, Spiro, Portais, Jean-Charles, Padro, Daniel, Ramos-Cabrer, Pedro, Carmeliet, Peter, Almeida, Angeles, Bolaños, Juan P.

“…The energy cost of neuronal activity is mainly sustained by glucose 1 , 2 . However, in an apparent paradox, neurons modestly metabolize glucose through…”
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Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke by Sánchez-Morán, Irene, Rodríguez, Cristina, Lapresa, Rebeca, Agulla, Jesús, Sobrino, Tomás, Castillo, José, Bolaños, Juan P, Almeida, Angeles

“…Failure of neurons to efficiently repair DNA double-strand breaks (DSBs) contributes to cerebral damage after stroke. However, the molecular machinery that…”
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Weak neuronal glycolysis sustains cognition and organismal fitness by Jimenez-Blasco, Daniel, Agulla, Jesús, Lapresa, Rebeca, Garcia-Macia, Marina, Bobo-Jimenez, Veronica, Garcia-Rodriguez, Dario, Manjarres-Raza, Israel, Fernandez, Emilio, Jeanson, Yannick, Khoury, Spiro, Portais, Jean-Charles, Padro, Daniel, Ramos-Cabrer, Pedro, Carmeliet, Peter, Almeida, Angeles, Bolaños, Juan P

“…The energy cost of neuronal activity is mainly sustained by glucose1,2. However, in an apparent paradox, neurons modestly metabolize glucose through…”
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Mn(II) complexes with sulfonamides as ligands. DNA interaction studies and nuclease activity by Macías, Benigno, Villa, María V, Lapresa, Rebeca, Alzuet, Gloria, Hernández-Gil, Javier, Sanz, Francisca

“…Sulfonamides derived from 8-aminoquinoline react with Mn(II) and Mn(III) salts to form Mn(II) complexes; the Mn(III) species are reduced to the divalent state…”
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Mn(II) complexes with sulfonamides as ligands by Macías, Benigno, Villa, María V., Lapresa, Rebeca, Alzuet, Gloria, Hernández-Gil, Javier, Sanz, Francisca

“…Sulfonamides derived from 8-aminoquinoline react with Mn(II) and Mn(III) salts to form Mn(II) complexes; the Mn(III) species are reduced to the divalent state…”
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