Search Results - "Lapraz, François"
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A Transcriptomic-Phylogenomic Analysis of the Evolutionary Relationships of Flatworms
Published in Current biology (18-05-2015)“…The interrelationships of the flatworms (phylum Platyhelminthes) are poorly resolved despite decades of morphological and molecular phylogenetic studies [1,…”
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The Drosophila actin nucleator DAAM is essential for left-right asymmetry
Published in PLoS genetics (01-04-2020)“…Left-Right (LR) asymmetry is essential for organ positioning, shape and function. Myosin 1D (Myo1D) has emerged as an evolutionary conserved chirality…”
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Characterization of the Drosophila Adult Hematopoietic System Reveals a Rare Cell Population With Differentiation and Proliferation Potential
Published in Frontiers in cell and developmental biology (13-10-2021)“…While many studies have described Drosophila embryonic and larval blood cells, the hematopoietic system of the imago remains poorly characterized and…”
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Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm
Published in PLoS genetics (01-12-2010)“…Echinoderms, which are phylogenetically related to vertebrates and produce large numbers of transparent embryos that can be experimentally manipulated, offer…”
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The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima
Published in PLoS biology (01-11-2014)“…Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but…”
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The mitochondrial genomes of the acoelomorph worms Paratomella rubra, Isodiametra pulchra and Archaphanostoma ylvae
Published in Scientific reports (12-05-2017)“…Acoels are small, ubiquitous - but understudied - marine worms with a very simple body plan. Their internal phylogeny is still not fully resolved, and the…”
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Insights into early animal evolution from the genome of the xenacoelomorph worm Xenoturbella bocki
Published in eLife (07-08-2024)“…The evolutionary origins of Bilateria remain enigmatic. One of the more enduring proposals highlights similarities between a cnidarian-like planula larva and…”
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Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo
Published in Development (Cambridge) (15-01-2010)“…Nodal factors play fundamental roles in induction and patterning of the mesoderm and endoderm in vertebrates, but whether this reflects an ancient role or one…”
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The complete mitochondrial genome of the geophilomorph centipede Strigamia maritima
Published in PloS one (20-03-2015)“…Strigamia maritima (Myriapoda; Chilopoda) is a species from the soil-living order of geophilomorph centipedes. The Geophilomorpha is the most speciose order of…”
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Light-sheet microscopy for everyone? Experience of building an OpenSPIM to study flatworm development
Published in BMC developmental biology (30-06-2016)“…Selective plane illumination microscopy (SPIM a type of light-sheet microscopy) involves focusing a thin sheet of laser light through a specimen at right…”
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RTK and TGF-β signaling pathways genes in the sea urchin genome
Published in Developmental biology (01-12-2006)“…The Receptor Tyrosine kinase (RTK) and TGF-β signaling pathways play essential roles during development in many organisms and regulate a plethora of cellular…”
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Put a tiger in your tank: the polyclad flatworm Maritigrella crozieri as a proposed model for evo-devo
Published in EvoDevo (09-10-2013)“…Polyclad flatworms are an early branching clade within the rhabditophoran Platyhelminthes. They provide an interesting system with which to explore the…”
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A deuterostome origin of the Spemann organiser suggested by Nodal and ADMPs functions in Echinoderms
Published in Nature communications (01-10-2015)“…During development of chordates, establishment of the body plan relies on the activity of an organizing centre located on the dorsal side of the embryo that…”
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The sea urchin kinome: A first look
Published in Developmental biology (01-12-2006)“…This paper reports a preliminary in silico analysis of the sea urchin kinome. The predicted protein kinases in the sea urchin genome were identified, annotated…”
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Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network
Published in PLoS biology (01-11-2009)“…Formation of the dorsal-ventral axis of the sea urchin embryo relies on cell interactions initiated by the TGFbeta Nodal. Intriguingly, although nodal…”
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The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo
Published in PLoS biology (01-09-2015)“…Specification of the dorsal-ventral axis in the highly regulative sea urchin embryo critically relies on the zygotic expression of nodal, but whether maternal…”
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Cis-regulatory analysis of nodal and maternal control of dorsal-ventral axis formation by Univin, a TGF-beta related to Vg1
Published in Development (Cambridge) (01-10-2007)“…The TGF-beta family member Nodal is essential for specification of the dorsal-ventral axis of the sea urchin embryo, but the molecular factors regulating its…”
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Brain bilateral asymmetry – insights from nematodes, zebrafish, and Drosophila
Published in Trends in neurosciences (Regular ed.) (01-10-2024)“…Stereotyped brain asymmetry, also known as laterality, is widespread and multiscale, encompassing asymmetrical molecular function, left–right (LR) asymmetrical…”
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A deuterostome origin of the Spemann organiser suggested by Nodal and ADMPs functions in Echinoderms
Published in Nature communications (19-11-2015)Get full text
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Lefty acts as an essential modulator of Nodal activity during sea urchin oral–aboral axis formation
Published in Developmental biology (01-08-2008)“…Nodal is a key player in the process regulating oral–aboral axis formation in the sea urchin embryo. Expressed early within an oral organizing centre, it is…”
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