Search Results - "Lapin, Morten"

Fragment size and level of cell-free DNA provide prognostic information in patients with advanced pancreatic cancer by Lapin, Morten, Oltedal, Satu, Tjensvoll, Kjersti, Buhl, Tove, Smaaland, Rune, Garresori, Herish, Javle, Milind, Glenjen, Nils Idar, Abelseth, Bente Kristin, Gilje, Bjørnar, Nordgård, Oddmund

“…It was recently demonstrated that the size of cell-free DNA (cfDNA) fragments that originates from tumor cells are shorter than cfDNA fragments that originates…”
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Extracellular vesicles as a potential source of tumor-derived DNA in advanced pancreatic cancer by Lapin, Morten, Tjensvoll, Kjersti, Nedrebø, Karoline, Taksdal, Eline, Janssen, Hans, Gilje, Bjørnar, Nordgård, Oddmund

“…Tumor-derived extracellular vesicles (EVs) are reported to contain nucleic acids, including DNA. Several studies have highlighted the potential of EV-derived…”
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Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing by Tjensvoll, Kjersti, Lapin, Morten, Gilje, Bjørnar, Garresori, Herish, Oltedal, Satu, Forthun, Rakel Brendsdal, Molven, Anders, Rozenholc, Yves, Nordgård, Oddmund

“…Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is…”
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Single-cell mRNA profiling reveals transcriptional heterogeneity among pancreatic circulating tumour cells by Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Javle, Milind, Smaaland, Rune, Gilje, Bjørnar, Nordgård, Oddmund

“…Single-cell mRNA profiling of circulating tumour cells may contribute to a better understanding of the biology of these cells and their role in the metastatic…”
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High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling by Øvestad, Irene Tveiterås, Engesæter, Birgit, Halle, Mari Kyllesø, Akbari, Saleha, Bicskei, Beatrix, Lapin, Morten, Austdal, Marie, Janssen, Emiel A M, Krakstad, Camilla, Lillesand, Melinda, Nordhus, Marit, Munk, Ane Cecilie, Gudlaugsson, Einar G

“…Implementation of high-risk human papilloma virus (HPV) screening and the increasing proportion of HPV vaccinated women in the screening program will reduce…”
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Monitoring of circulating tumour DNA in advanced pancreatic ductal adenocarcinoma predicts clinical outcome and reveals disease progression earlier than radiological imaging by Edland, Karin Hestnes, Tjensvoll, Kjersti, Oltedal, Satu, Dalen, Ingvild, Lapin, Morten, Garresori, Herish, Glenjen, Nils, Gilje, Bjørnar, Nordgård, Oddmund

“…Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a need for better tools to guide treatment selection and follow-up. The aim of this…”
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Prognostic value of disseminated tumor cells in unresectable pancreatic ductal adenocarcinoma: a prospective observational study by Nordgård, Oddmund, Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Edland, Karin Hestnes, Neverdahl, Nicolay Bore, Fostenes, Dmitrij, Garresori, Herish, Glenjen, Nils, Smaaland, Rune, Gilje, Bjørnar

“…Although pancreatic ductal adenocarcinoma (PDAC) rarely metastasizes to the skeleton, disseminated tumor cells have been detected in bone marrow samples from…”
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The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer by Hartung, Anne-Mette, Swensen, Jeff, Uriz, Inaki E, Lapin, Morten, Kristjansdottir, Karen, Petersen, Ulrika S S, Bang, Jeanne Mari V, Guerra, Barbara, Andersen, Henriette Skovgaard, Dobrowolski, Steven F, Carey, John C, Yu, Ping, Vaughn, Cecily, Calhoun, Amy, Larsen, Martin R, Dyrskjøt, Lars, Stevenson, David A, Andresen, Brage S

“…Costello syndrome (CS) may be caused by activating mutations in codon 12/13 of the HRAS proto-oncogene. HRAS p.Gly12Val mutations have the highest transforming…”
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Comprehensive ctDNA Measurements Improve Prediction of Clinical Outcomes and Enable Dynamic Tracking of Disease Progression in Advanced Pancreatic Cancer by Lapin, Morten, Edland, Karin H, Tjensvoll, Kjersti, Oltedal, Satu, Austdal, Marie, Garresori, Herish, Rozenholc, Yves, Gilje, Bjørnar, Nordgård, Oddmund

“…Circulating tumor DNA (ctDNA) has emerged as a promising tumor-specific biomarker in pancreatic cancer, but current evidence of the clinical potential of ctDNA…”
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MINDEC-An Enhanced Negative Depletion Strategy for Circulating Tumour Cell Enrichment by Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Buhl, Tove, Gilje, Bjørnar, Smaaland, Rune, Nordgård, Oddmund

“…Most current methods of circulating tumour cell (CTC) enrichment target the epithelial protein EpCAM, which is commonly expressed in adenocarcinoma cells…”
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Clinical relevance of circulating KRAS mutated DNA in plasma from patients with advanced pancreatic cancer by Tjensvoll, Kjersti, Lapin, Morten, Buhl, Tove, Oltedal, Satu, Steen-Ottosen Berry, Katrine, Gilje, Bjørnar, Søreide, Jon Arne, Javle, Millind, Nordgård, Oddmund, Smaaland, Rune

“…We used KRAS mutations to investigate the clinical relevance of circulating tumor DNA (ctDNA) measurements in patients with advanced pancreatic cancer…”
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Abstract 5593: The fragment size and levels of cell-free DNA provide prognostic information in patients with advanced pancreatic cancer by Lapin, Morten, Oltedal, Satu, Tjensvoll, Kjersti, Buhl, Tove, Smaaland, Rune, Glenjen, Nils, Gilje, Bjørnar, Nordgård, Oddmund

“…Purpose: To investigate the prognostic value of cell-free DNA (cfDNA) fragment size and cfDNA levels in patients with advanced pancreatic cancer. Methods:…”
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Mutation-Agnostic Detection of Colorectal Cancer Using Liquid Biopsy-Based Methylation-Specific Signatures by Gouda, Mohamed A, Duose, Dzifa Y, Lapin, Morten, Zalles, Stephanie, Huang, Helen J, Xi, Yuanxin, Zheng, Xiaofeng, Aldesoky, Amira I, Alhanafy, Alshimaa M, Shehata, Mohamed A, Wang, Jing, Kopetz, Scott, Meric-Bernstam, Funda, Wistuba, Ignacio I, Luthra, Rajyalakshmi, Janku, Filip

“…Abstract Detection of methylation patterns in circulating tumor DNA (ctDNA) can offer a novel approach for cancer diagnostics given the unique signature for…”
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Abstract LB-252: Single-cell mRNA profiling reveal transcriptional heterogeneity among pancreatic circulating tumor cells by Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Javle, Milind, Smaaland, Rune, Gilje, Bjørnar, Nordgård, Oddmund

“…Background: Single-cell analysis of the transcriptional heterogeneity of circulating tumor cells have the prospect of better understanding the biology of these…”
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Abstract 2287: Circulating extracellular vesicles from patients with advanced pancreatic cancer contain low levels of tumor-derived DNA by Lapin, Morten, Tjensvoll, Kjersti, Nedrebø, Karoline, Taksdal, Eline, Janssen, Hans, Gilje, Bjørnar, Nordgard, Oddmund

“…Purpose: Extracellular vesicles (EVs) have been shown to contain nucleic acids, including DNA. Several studies have highlighted the potential of EV-derived DNA…”
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Extracellular vesicles as a potential source of tumor-derived DNA in advanced pancreatic cancer by Morten Lapin, Kjersti Tjensvoll, Karoline Nedrebø, Eline Taksdal, Hans Janssen, Bjørnar Gilje, Oddmund Nordgård

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Abstract 734: Monitoring of dynamic changes and clonal evolution in circulating tumor DNA from patients with IDH-mutated cholangiocarcinoma treated with IDH inhibitors by Lapin, Morten, Huang, Helen J., Javle, Milind, Shroff, Rachna T., Pant, Shubham, Raina, Anjali, Madwani, Kiran, Holley, Veronica R., Call, S. Greg, Lanman, Richard B., Kwong, Lawrence, Meric-Bernstam, Funda, Raymond, Victoria M., Janku, Filip

“…Background: IDH mutations are prevalent in up to 30% of patients with cholangiocarcinoma and IDH inhibitors are in the late stage of clinical development…”
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Sensitive detection of plasma mutations using a novel tag-based error suppression sequencing method by Lapin, Morten, Tjensvoll, Kjersti, Oltedal, Satu, Rozenholc, Yves, Buhl, Tove, Garresori, Herish, Javle, Milind, Molven, Anders, Gilje, Bjørnar, Nordgård, Oddmund

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Real-world experience of the decentralized MSK-ACCESS powered with SOPHiA DDM solution by Klemm, Florian, Mohammad, Fuad, Pradines, Anne, Keller, Laura, Kazdal, Daniel, Ball, Markus, Lapin, Morten, Nordgård, Oddmund, du Parcq, Persephone, Heathman, Alasdair, Hensel, Sasha, Gerrard, Gareth, Wheelan, Justin, Antoniou, Eric, Khan, Faisal, Faridi, Rehan, Ryder, Chloe, Xu, Zhenyu

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Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System by Nordgård, Oddmund, Brendsdal Forthun, Rakel, Lapin, Morten, Grønberg, Bjørn Henning, Kalland, Karl Henning, Kopperud, Reidun Kristin, Thomsen, Liv Cecilie Vestrheim, Tjensvoll, Kjersti, Gilje, Bjørnar, Gjertsen, Bjørn Tore, Hovland, Randi

“…Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers…”
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