Search Results - "Laperche, Yannick"

Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice by Fourcot, Agnès, Couchie, Dominique, Chobert, Marie-Noele, Zafrani, Elie-Serge, Mavier, Philippe, Laperche, Yannick, Brouillet, Arthur

“…The Gas6/Axl pathway has been increasingly implicated in regeneration and tissue repair and, recently, in the control of innate immunity. In liver, we have…”
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Growth arrest-specific protein 6 deficiency impairs liver tissue repair after acute toxic hepatitis in mice by Lafdil, Fouad, Chobert, Marie-Noële, Deveaux, Vanessa, Zafrani, Elie-Serge, Mavier, Philippe, Nakano, Toru, Laperche, Yannick, Brouillet, Arthur

“…Background/Aims Resident macrophages and myofibroblasts derived from hepatic stellate cells play a key role in liver wound healing. We previously reported that…”
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Induction of Gas6 protein in CCl4‐induced rat liver injury and anti‐apoptotic effect on hepatic stellate cells by Lafdil, Fouad, Chobert, Marie Noële, Couchie, Dominique, Brouillet, Arthur, Zafrani, Elie Serge, Mavier, Philippe, Laperche, Yannick

“…The protein product of the growth arrest–specific gene 6 (Gas6) is a secreted ligand for tyrosine kinase receptors, among which Axl is the most widely…”
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Expression of Stromal Cell-Derived Factor-1 and of Its Receptor CXCR4 in Liver Regeneration from Oval Cells in Rat by Mavier, Philippe, Martin, Nadine, Couchie, Dominique, Préaux, Anne-Marie, Laperche, Yannick, Zafrani, Elie Serge

“…Stromal cell-derived factor-1 is a chemokine that plays a major role during embryogenesis. Since stromal cell-derived factor-1 and its unique receptor CXCR4…”
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Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species by Chikhi, Naı̈ma, Holic, Nathalie, Guellaen, Georges, Laperche, Yannick

“…Gamma-glutamyl transpeptidase (GGT) is an enzyme located at the external surface of epithelial cells. It initiates extracellular glutathione (GSH) breakdown,…”
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Liver precursor cells increase hepatic fibrosis induced by chronic carbon tetrachloride intoxication in rats by Chobert, Marie-Noële, Couchie, Dominique, Fourcot, Agnès, Zafrani, Elie-Serge, Laperche, Yannick, Mavier, Philippe, Brouillet, Arthur

“…Hepatic fibrosis, the major complication of virtually all types of chronic liver damage, usually begins in portal areas, and its severity has been correlated…”
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Liver precursor cells increase hepatic fibrosis induced by chronic carbon tetrachloride intoxication in rats: LPC aggravates liver CCl4-induced fibrosis by Chobert, Marie-Noële, Couchie, Dominique, Fourcot, Agnès, Zafrani, Elie-Serge, Laperche, Yannick, Mavier, Philippe, Brouillet, Arthur

“…Hepatic fibrosis, the major complication of virtually all types of chronic liver damage, usually begins in portal areas, and its severity has been correlated…”
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γ-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells by Zhang, Hongqiao, Liu, Honglei, Dickinson, Dale A., Liu, Rui-Ming, Postlethwait, Edward M., Laperche, Yannick, Forman, Henry Jay

“…γ-Glutamyl transpeptidase (GGT) plays key roles in glutathione homeostasis and metabolism of glutathione S-conjugates. Rat GGT is transcribed via five tandemly…”
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4-Hydroxynonenal induces rat gamma-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling by Zhang, Hongqiao, Liu, Honglei, Iles, Karen E, Liu, Rui-Ming, Postlethwait, Edward M, Laperche, Yannick, Forman, Henry Jay

“…Gamma-glutamyl transpeptidase (GGT) plays critical roles in glutathione homeostasis and metabolism. Rat GGT is a single-copy gene from which seven types of GGT…”
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Growth arrest-specific protein 6 deficiency impairs liver tissue repair after acute toxic hepatitis in mice: Gas6 deficiency impairs hepatic wound healing by Lafdil, Fouad, Chobert, Marie-Noële, Deveaux, Vanessa, Zafrani, Elie-Serge, Mavier, Philippe, Nakano, Toru, Laperche, Yannick, Brouillet, Arthur

“…BACKGROUND/AIMS: Resident macrophages and myofibroblasts derived from hepatic stellate cells play a key role in liver wound healing. We previously reported…”
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Origin of liver murine oval cells by Laperche, Yannick

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Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2 by Preaux, Anne-Marie, D'Ortho, Marie-Pia, Bralet, Marie-Pierre, Laperche, Yannick, Mavier, Philippe

“…Liver fibrosis is potentially reversible after removal of the injurious agent. Fibrosis resolution is characterized by apoptosis of hepatic myofibroblasts and…”
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Expression and Role of Gas6 Protein and of Its Receptor Axl in Hepatic Regeneration From Oval Cells in the Rat by Couchie, Dominique, Lafdil, Fouad, Martin–Garcia, Nadine, Laperche, Yannick, Zafrani, Elie Serge, Mavier, Philippe

“…Background & Aims: The growth arrest-specific gene 6 (Gas6) protein is a vitamin K-dependent protein that binds to the Axl subfamily of tyrosine kinase…”
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In vitro differentiation of WB-F344 rat liver epithelial cells into the biliary lineage by Couchie, Dominique, Holic, Nathalie, Chobert, Marie-Noële, Corlu, Anne, Laperche, Yannick

“…Differentiation of hepatic precursor cells in the biliary lineage has rarely been investigated, owing to the lack of convenient in vitro models. In this study,…”
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Oval cells and liver regeneration by Laperche, Yannick

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4-Hydroxynonenal Induces Rat {gamma}-Glutamyl Transpeptidase through Mitogen-Activated Protein Kinase-Mediated Electrophile Response Element/Nuclear Factor Erythroid 2-Related Factor 2 Signaling by Zhang, Hongqiao, Liu, Honglei, Iles, Karen E, Liu, Rui-Ming, Postlethwait, Edward M, Laperche, Yannick, Forman, Henry Jay

“…Gamma-glutamyl transpeptidase (GGT) plays critical roles in glutathione homeostasis and metabolism. Rat GGT is a single-copy gene from which seven types of GGT…”
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The expression of [gamma]-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress by Mikkelsen, Idun Merete, Mortensen, Bente, Laperche, Yannick, Huseby, Nils-erik

“…Gamma glutamyltransferase (GGT) is a plasma membrane bound enzyme that initiates the degradation of glutathione. The presence of several promoters in the rat…”
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Differential Expression of the Rat γ-Glutamyl Transpeptidase Gene Promoters along with Differentiation of Hepatoblasts into Biliary or Hepatocytic Lineage by Holic, Nathalie, Suzuki, Takanobu, Corlu, Anne, Couchie, Dominique, Chobert, Marie Noële, Guguen-Guillouzo, Christiane, Laperche, Yannick

“…γ-Glutamyl transpeptidase (GGT), a major enzyme of glutathione (GSH) homeostasis, is often used as a biliary marker to follow the differentiation of hepatic…”
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The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress by Mikkelsen, Idun Merete, Mortensen, Bente, Laperche, Yannick, Huseby, Nils-Erik

“…Gamma glutamyltransferase (GGT) is a plasma membrane bound enzyme that initiates the degradation of glutathione. The presence of several promoters in the rat…”
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275 Expression of stromal-derived factor-1 and of its receptor CXCR4 in hepatic regeneration from oval cells by Mavier, Philippe, Martin, Nadine, Couchie, Dominique, Preaux, Anne M., Laperche, Yannick, Zafrani, Elie S.

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