Search Results - "Lapenna, Domenico"

Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging by Lapenna, Domenico

“…The tripeptide glutathione (GSH), namely γ-L-glutamyl-L-cysteinyl-glycine, is an ubiquitous low-molecular weight thiol nucleophile and reductant of utmost…”
Get full text

Circadian blood pressure changes and cardiovascular risk in elderly-treated hypertensive patients by Pierdomenico, Sante D, Pierdomenico, Anna M, Coccina, Francesca, Lapenna, Domenico, Porreca, Ettore

“…The independent prognostic significance of circadian blood pressure (BP) changes is unclear. We investigated the association between circadian BP changes and…”
Get full text

Impact of migraine on fibromyalgia symptoms by Giamberardino, Maria Adele, Affaitati, Giannapia, Martelletti, Paolo, Tana, Claudio, Negro, Andrea, Lapenna, Domenico, Curto, Martina, Schiavone, Cosima, Stellin, Luisa, Cipollone, Francesco, Costantini, Raffaele

“…Background Fibromyalgia (FMS) and high frequency episodic/chronic migraine (M) very frequently co-occur, suggesting common pathophysiological mechanisms; both…”
Get full text

Effects of topical vs injection treatment of cervical myofascial trigger points on headache symptoms in migraine patients: a retrospective analysis by Affaitati, Giannapia, Costantini, Raffaele, Tana, Claudio, Lapenna, Domenico, Schiavone, Cosima, Cipollone, Francesco, Giamberardino, Maria Adele

“…Background In migraine patients with cervical myofascial trigger points whose target areas coincide with migraine sites (M + cTrPs), TrP anesthetic injection…”
Get full text

A prospective evaluation of iron deficiency anemia in the GI endoscopy setting: role of standard endoscopy, videocapsule endoscopy, and CT-enteroclysis by Milano, Angelo, MD, PhD, Balatsinou, Chrysanthi, MD, Filippone, Antonella, MD, Caldarella, Maria Pia, MD, PhD, Laterza, Francesco, MD, Lapenna, Domenico, MD, Pierdomenico, Sante Donato, MD, Pace, Fabio, MD, Cuccurullo, Franco, MD, Neri, Matteo, MD

“…Background Iron deficiency anemia (IDA) is a frequently encountered condition in clinical practice. After conventional endoscopy, the cause of anemia remains…”
Get full text

Antioxidant Therapy in Coronavirus Disease 2019: The Crucial Role of Early Treatment and Antioxidant Typology by Lapenna, Domenico

Get full text

A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: Evaluation of pain and somatic pain thresholds by Affaitati, Giannapia, MD, PhD, Fabrizio, Alessandra, MD, Savini, Antonella, MD, Lerza, Rosanna, MD, Tafuri, Emmanuele, MD, Costantini, Raffaele, MD, PhD, Lapenna, Domenico, MD, Giamberardino, Maria Adele, MD

“…Abstract Background : Myofascial pain syndrome (MPS), a regional pain condition caused by trigger points in muscle or muscle fascia, produces muscle pain,…”
Get full text

Antioxidant therapy in COVID-19: The crucial role of early treatment and antioxidant typology by Lapenna, Domenico

Get full text

Prediction of carotid plaques in hypertensive patients by risk factors, left ventricular hypertrophy, and epicardial adipose tissue thickness by Pierdomenico, Sante D., Mancini, Mariantonietta, Cuccurullo, Chiara, Guglielmi, Maria D., Pierdomenico, Anna M., Di Nicola, Marta, Di Carlo, Silvio, Lapenna, Domenico, Cuccurullo, Franco

“…Hypertension and other risk factors (RFs) predispose to carotid plaques (CPs). An association between left ventricular hypertrophy (LVH) or epicardial adipose…”
Get full text

Serum albumin and biomolecular oxidative damage of human atherosclerotic plaques by Lapenna, Domenico, Ciofani, Giuliano, Ucchino, Sante, Pierdomenico, Sante Donato, Cuccurullo, Chiara, Giamberardino, Maria Adele, Cuccurullo, Franco

“…To investigate the association of serum albumin (SA) with oxidative damage of human atherosclerotic plaques and the severity of atherosclerosis. Correlation of…”
Get full text

Chromium and human low-density lipoprotein oxidation by Lapenna, Domenico, Ciofani, Giuliano

“…•Cr(VI) can induce human LDL oxidation at lysosomal acidic pH of 4.5.•Cr(VI)-induced LDL oxidation is counteracted by metal chelators and chain-breaking…”
Get full text

Glutathione-related antioxidant defenses in human atherosclerotic plaques by LAPENNA, D, DE GIOIA, S, CIOFANI, G, MEZZETTI, A, UCCHINO, S, CALAFIORE, A. M, NAPOLITANO, A. M, DI ILIO, C, CUCCURULLO, F

“…Oxidative stress, resulting from an antioxidant/prooxidant imbalance, seems to be crucial in atherogenesis. Recent evidence has emerged, however, of a…”
Get full text

Viscero-visceral hyperalgesia: Characterization in different clinical models by Giamberardino, Maria Adele, Costantini, Raffaele, Affaitati, Giannapia, Fabrizio, Alessandra, Lapenna, Domenico, Tafuri, Emmanuele, Mezzetti, Andrea

“…Co-existing algogenic conditions in two internal organs in the same patient may mutually enhance pain symptoms (viscero-visceral hyperalgesia). The present…”
Get full text

Glutathione metabolic status in the aged rabbit aorta by Lapenna, Domenico, Ciofani, Giuliano, Giamberardino, Maria Adele

“…It is not known whether aging alters glutathione metabolic status of the mammalian arterial tissue favoring vascular oxidative stress and dysfunction. Thus we…”
Get full text

Antioxidant properties of omeprazole by Lapenna, Domenico, Gioia, Sergio de, Ciofani, Giuliano, Festi, Davide, Cuccurullo, Franco

“…Potential antioxidant properties of therapeutically achievable concentrations of the protonated, active form of omeprazole (OM) were investigated in vitro at…”
Get full text

Twenty-four-hour autonomic nervous function in sustained and “white coat” hypertension by Pierdomenico, Sante D., Bucci, Anna, Costantini, Fabrizio, Lapenna, Domenico, Cuccurullo, Franco, Mezzetti, Andrea

“…Background It is unknown whether “white coat” hypertension, also known as isolated clinic hypertension, shares similarities in pathophysiologic background with…”
Get full text

Oxidative stress-related mechanisms affecting response to aspirin in diabetes mellitus by Santilli, Francesca, Lapenna, Domenico, La Barba, Sara, Davì, Giovanni

“…Type 2 diabetes mellitus (T2DM) is a major cardiovascular risk factor. Persistent platelet activation plays a key role in atherothrombosis in T2DM. However,…”
Get full text

Impaired glutathione-related antioxidant defenses in the arterial tissue of diabetic patients by Lapenna, Domenico, Ciofani, Giuliano, Calafiore, Antonio Maria, Cipollone, Francesco, Porreca, Ettore

“…We studied the specific enzymatic activities of selenium-dependent (GSH-Px) and -independent (GST-Px) glutathione peroxidase, glutathione reductase (GSSG-Red),…”
Get full text

Evidence for oxidative and not reductive stress in the aged rabbit heart by Lapenna, Domenico, Ciofani, Giuliano, Lelli Chiesa, Pierluigi, Porreca, Ettore

“…Reductive stress, which is due to a paradoxical excess of antioxidants such as reduced glutathione (GSH) and GSH-related enzymes associated with decreased…”
Get full text

Iron status and oxidative stress in the aged rabbit heart by Lapenna, Domenico, Ciofani, Giuliano, Pierdomenico, Sante Donato, Giamberardino, Maria Adele, Porreca, Ettore

“…Altered iron status may be relevant to the pathophysiology of aging. We have assessed redox-active catalytic low molecular weight iron (LMWI), non-heme iron…”
Get full text