Search Results - "Lapaquette, Pierre"
-
1
Cellular and Molecular Connections between Autophagy and Inflammation
Published in Mediators of Inflammation (01-01-2015)“…Autophagy is an intracellular catabolic pathway essential for the recycling of proteins and larger substrates such as aggregates, apoptotic corpses, or…”
Get full text
Journal Article -
2
Spontaneous Prophage Induction Contributes to the Production of Membrane Vesicles by the Gram-Positive Bacterium Lacticaseibacillus casei BL23
Published in mBio (26-10-2022)“…The formation of membrane vesicles (MVs) by Gram-positive bacteria has gained increasing attention over the last decade. Recently, models of vesicle formation…”
Get full text
Journal Article -
3
Sumoylation of human argonaute 2 at lysine-402 regulates its stability
Published in PloS one (18-07-2014)“…Gene silencing by small RNAs has emerged as a powerful post-transcriptional regulator of gene expression, however processes underlying regulation of the small…”
Get full text
Journal Article -
4
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation
Published in Genome research (01-10-2013)“…Despite numerous studies on specific sumoylated transcriptional regulators, the global role of SUMO on chromatin in relation to transcription regulation…”
Get full text
Journal Article -
5
Shigella entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation
Published in eLife (12-12-2017)“…Disruption of the sumoylation/desumoylation equilibrium is associated with several disease states such as cancer and infections, however the mechanisms…”
Get full text
Journal Article -
6
Resveratrol Favors Adhesion and Biofilm Formation of Lacticaseibacillus paracasei subsp. paracasei Strain ATCC334
Published in International journal of molecular sciences (30-07-2020)“…Bacterial strains of the Lactobacillaceae family are widely used as probiotics for their multifaceted potential beneficial properties. However, no official…”
Get full text
Journal Article -
7
Intestinal release of biofilm-like microcolonies encased in calcium-pectinate beads increases probiotic properties of Lacticaseibacillus paracasei
Published in NPJ biofilms and microbiomes (28-10-2020)“…In this study, we show that calcium pectinate beads (CPB) allow the formation of 20 µm spherical microcolonies of the probiotic bacteria Lacticaseibacillus…”
Get full text
Journal Article -
8
Resveratrol-Induced Xenophagy Promotes Intracellular Bacteria Clearance in Intestinal Epithelial Cells and Macrophages
Published in Frontiers in immunology (14-01-2019)“…Autophagy is a lysosomal degradation process that contributes to host immunity by eliminating invasive pathogens and the modulating inflammatory response…”
Get full text
Journal Article -
9
Membrane protective role of autophagic machinery during infection of epithelial cells by Candida albicans
Published in Gut microbes (01-01-2022)“…Candida albicans (C. albicans) is an opportunistic pathogen causing infections ranging from superficial to life-threatening disseminated infections. In a…”
Get full text
Journal Article -
10
Long-term intake of Lactobacillus helveticus enhances bioavailability of omega-3 fatty acids in the mouse retina
Published in NPJ biofilms and microbiomes (18-01-2024)“…Omega-3 (n-3) polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA), are required for the structure and function of the retina. Several…”
Get full text
Journal Article -
11
Risk predisposition for Crohn disease: A "ménage à trois" combining IRGM allele, miRNA and xenophagy
Published in Autophagy (01-07-2011)“…Susceptibility to Crohn disease (CD), an inflammatory bowel disease, is influenced by common variants at many loci like the exonic synonymous IRGM SNP…”
Get full text
Journal Article -
12
You shall not pass! Protective role of autophagic machinery in response to plasma membrane damage triggered by Candida albicans invasion
Published in Autophagy (02-11-2022)“…Candida albicans (C. albicans) is an opportunistic pathogen causing infections ranging from superficial to life-threatening dissemination, in which C. albicans…”
Get full text
Journal Article -
13
Reciprocal interactions between gut microbiota and autophagy
Published in World journal of gastroenterology : WJG (28-12-2021)“…A symbiotic relationship has set up between the gut microbiota and its host in the course of evolution, forming an interkingdom consortium. The gut offers a…”
Get full text
Journal Article -
14
Defects in autophagy favour adherent‐invasive Escherichia coli persistence within macrophages leading to increased pro‐inflammatory response
Published in Cellular microbiology (01-06-2012)“…Summary Ileal lesions in Crohn's disease (CD) patients are abnormally colonized by pathogenic adherent‐invasive Escherichia coli (AIEC). AIEC bacteria are able…”
Get full text
Journal Article -
15
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
Published in Nature genetics (01-03-2011)“…Susceptibility to Crohn's disease, a complex inflammatory disease, is influenced by common variants at many loci. The common exonic synonymous SNP (c.313C>T)…”
Get full text
Journal Article -
16
Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly
Published in Cellular microbiology (01-01-2010)“…Ileal lesions in Crohn's disease (CD) patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC) able to invade and to replicate within…”
Get full text
Journal Article -
17
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing
Published in Nature immunology (01-02-2016)“…Sumolyation regulates wide-ranging biological processes, but its influence on innate immunity is unclear. Amigorena and colleagues show that sumoylation…”
Get full text
Journal Article -
18
"Candida Albicans Interactions With The Host: Crossing The Intestinal Epithelial Barrier"
Published in Tissue barriers (01-01-2019)“…Formerly a commensal organism of the mucosal surfaces of most healthy individuals, Candida albicans is an opportunistic pathogen that causes infections ranging…”
Get full text
Journal Article -
19
Etiology of Crohn’s disease: many roads lead to autophagy
Published in Journal of molecular medicine (Berlin, Germany) (01-09-2012)“…Crohn’s disease is a complex multifactor diseases that occur in individuals with genetic predisposition in whom environmental and microbial triggers cause a…”
Get full text
Journal Article -
20
Abnormalities in the Handling of Intracellular Bacteria in Crohnʼs Disease
Published in Journal of clinical gastroenterology (01-09-2010)“…Ileal lesions in Crohnʼs disease (CD) patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC) able to invade and to replicate within…”
Get full text
Journal Article