Search Results - "Lao, H"

Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study by Staaf, Johan, Glodzik, Dominik, Bosch, Ana, Vallon-Christersson, Johan, Reuterswärd, Christel, Häkkinen, Jari, Degasperi, Andrea, Amarante, Tauanne Dias, Saal, Lao H., Hegardt, Cecilia, Stobart, Hilary, Ehinger, Anna, Larsson, Christer, Rydén, Lisa, Loman, Niklas, Malmberg, Martin, Kvist, Anders, Ehrencrona, Hans, Davies, Helen R., Borg, Åke, Nik-Zainal, Serena

“…Whole-genome sequencing (WGS) brings comprehensive insights to cancer genome interpretation. To explore the clinical value of WGS, we sequenced 254…”
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On comparing Hecke eigenvalues of cusp forms by Lao, H. X.

“…Let f(z) be a primitive holomorphic cusp form of even integral weight k for the full modular group. Denote its n th Hecke eigenvalue or normalized Fourier…”
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Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease by Olsson, Eleonor, Winter, Christof, George, Anthony, Chen, Yilun, Howlin, Jillian, Tang, Man‐Hung Eric, Dahlgren, Malin, Schulz, Ralph, Grabau, Dorthe, van Westen, Danielle, Fernö, Mårten, Ingvar, Christian, Rose, Carsten, Bendahl, Pär‐Ola, Rydén, Lisa, Borg, Åke, Gruvberger‐Saal, Sofia K, Jernström, Helena, Saal, Lao H

“…Metastatic breast cancer is usually diagnosed after becoming symptomatic, at which point it is rarely curable. Cell‐free circulating tumor DNA (ctDNA) contains…”
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Tumor Characteristics and Molecular Subtypes in Breast Cancer Screening with Digital Breast Tomosynthesis: The Malmö Breast Tomosynthesis Screening Trial by Johnson, Kristin, Zackrisson, Sophia, Rosso, Aldana, Sartor, Hanna, Saal, Lao H, Andersson, Ingvar, Lång, Kristina

“…Background Screening accuracy can be improved with digital breast tomosynthesis (DBT). To further evaluate DBT in screening, it is important to assess the…”
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Clinical associations of ESR2 (estrogen receptor beta) expression across thousands of primary breast tumors by Dalal, Hina, Dahlgren, Malin, Gladchuk, Sergii, Brueffer, Christian, Gruvberger-Saal, Sofia K., Saal, Lao H.

“…Estrogen receptor alpha (ERα, encoded by ESR1 ) is a well-characterized transcription factor expressed in more than 75% of breast tumors and is the key…”
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On the asymptotics of coefficients of Rankin–Selberg L-functions by Lao, H., Zhu, H.

“…Let f and g be two different holomorphic cusp froms or Maass cusp forms for the full modular group S L ( 2 , Z ) . We are interested in coefficients of…”
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Serum selenium, selenoprotein P and glutathione peroxidase 3 as predictors of mortality and recurrence following breast cancer diagnosis: A multicentre cohort study by Demircan, Kamil, Bengtsson, Ylva, Sun, Qian, Brange, Annie, Vallon-Christersson, Johan, Rijntjes, Eddy, Malmberg, Martin, Saal, Lao H., Rydén, Lisa, Borg, Åke, Manjer, Jonas, Schomburg, Lutz

“…The trace element selenium is of essential importance for the synthesis of a set of redox active proteins. We investigated three complementary serum selenium…”
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Features of increased malignancy in eosinophilic clear cell renal cell carcinoma by Nilsson, Helén, Lindgren, David, Axelson, Håkan, Brueffer, Christian, Saal, Lao H, Lundgren, Jaana, Johansson, Martin E

“…Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel–Lindau tumour suppressor, the…”
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NF1‐mutated melanoma tumors harbor distinct clinical and biological characteristics by Cirenajwis, Helena, Lauss, Martin, Ekedahl, Henrik, Törngren, Therese, Kvist, Anders, Saal, Lao H., Olsson, Håkan, Staaf, Johan, Carneiro, Ana, Ingvar, Christian, Harbst, Katja, Hayward, Nicholas K., Jönsson, Göran

“…In general, melanoma can be considered as a UV‐driven disease with an aggressive metastatic course and high mutational load, with only few tumors (acral,…”
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The mutational landscape of the SCAN‐B real‐world primary breast cancer transcriptome by Brueffer, Christian, Gladchuk, Sergii, Winter, Christof, Vallon‐Christersson, Johan, Hegardt, Cecilia, Häkkinen, Jari, George, Anthony M, Chen, Yilun, Ehinger, Anna, Larsson, Christer, Loman, Niklas, Malmberg, Martin, Rydén, Lisa, Borg, Åke, Saal, Lao H

“…Breast cancer is a disease of genomic alterations, of which the panorama of somatic mutations and how these relate to subtypes and therapy response is…”
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p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes by Pappas, Kyrie, Xu, Jia, Zairis, Sakellarios, Resnick-Silverman, Lois, Abate, Francesco, Steinbach, Nicole, Ozturk, Sait, Saal, Lao H, Su, Tao, Cheung, Pamela, Schmidt, Hank, Aaronson, Stuart, Hibshoosh, Hanina, Manfredi, James, Rabadan, Raul, Parsons, Ramon

“…is the most commonly mutated tumor suppressor gene and its mutation drives tumorigenesis. Using ChIP-seq for p53 in the absence of acute cell stress, we found…”
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Activation of the PI3K Pathway in Cancer Through Inhibition of PTEN by Exchange Factor P-REX2a by Fine, Barry, Hodakoski, Cindy, Koujak, Susan, Su, Tao, Saal, Lao H, Maurer, Matthew, Hopkins, Benjamin, Keniry, Megan, Sulis, Maria Luisa, Mense, Sarah, Hibshoosh, Hanina, Parsons, Ramon

“…PTEN (phosphatase and tensin homolog on chromosome 10) is a tumor suppressor whose cellular regulation remains incompletely understood. We identified…”
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Preoperative ctDNA Levels Are Associated With Poor Overall Survival in Patients With Ovarian Cancer by DOBILAS, ARTURAS, CHEN, YILUN, BRUEFFER, CHRISTIAN, LEANDERSSON, PIA, SAAL, LAO H., BORGFELDT, CHRISTER

“…Background/Aim: Circulating tumor DNA (ctDNA), which is shed from cancer cells into the bloodstream, offers a potential minimally invasive approach for cancer…”
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Proteomic profiling reveals that ESR1 mutations enhance cyclin-dependent kinase signaling by De Marchi, Tommaso, Lai, Chun-Fui, Simmons, Georgia M., Goldsbrough, Isabella, Harrod, Alison, Lam, Thai, Buluwela, Lakjaya, Kjellström, Sven, Brueffer, Christian, Saal, Lao H., Malmström, Johan, Ali, Simak, Niméus, Emma

“…Three quarters of all breast cancers express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine…”
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TopHat-Recondition: a post-processor for TopHat unmapped reads by Brueffer, Christian, Saal, Lao H

“…TopHat is a popular spliced junction mapper for RNA sequencing data, and writes files in the BAM format - the binary version of the Sequence Alignment/Map…”
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Sun-as-a-star Study of an X-class Solar Flare with Spectroscopic Observations of CHASE by Ma, Y. L., Lao, Q. H., Cheng, X., Wang, B. T., Zhao, Z. H., Rao, S. H., Li, C., Ding, M. D.

“…Abstract Sun-as-a-star spectroscopic characteristics of solar flares can be used as a benchmark for the detection and analysis of stellar flares. Here, we…”
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Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity by Saal, Lao H, Johansson, Peter, Holm, Karolina, Gruvberger-Saal, Sofia K, She, Qing-Bai, Maurer, Matthew, Koujak, Susan, Ferrando, Adolfo A, Malmström, Per, Memeo, Lorenzo, Isola, Jorma, Bendahl, Pär-Ola, Rosen, Neal, Hibshoosh, Hanina, Ringnér, Markus, Borg, Åke, Parsons, Ramon

“…Pathway-specific therapy is the future of cancer management. The oncogenic phosphatidylinositol 3-kinase (PI3K) pathway is frequently activated in solid…”
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Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer by Li, Yanni, Sundquist, Kristina, Vats, Sakshi, Hong, Mun-Gwan, Wang, Xiao, Chen, Yilun, Hedelius, Anna, Saal, Lao H, Sundquist, Jan, Memon, Ashfaque A

“…Abstract Background Breast cancer is, despite screening, not always detected early enough and is together with other tumor types known to shed genetic…”
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CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers by Olsson, Eleonor, Honeth, Gabriella, Bendahl, Pär-Ola, Saal, Lao H, Gruvberger-Saal, Sofia, Ringnér, Markus, Vallon-Christersson, Johan, Jönsson, Göran, Holm, Karolina, Lövgren, Kristina, Fernö, Mårten, Grabau, Dorthe, Borg, Ake, Hegardt, Cecilia

“…The CD44 cell adhesion molecule is aberrantly expressed in many breast tumors and has been implicated in the metastatic process as well as in the putative…”
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Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling by Roswall, Pernilla, Bocci, Matteo, Bartoschek, Michael, Li, Hong, Kristiansen, Glen, Jansson, Sara, Lehn, Sophie, Sjölund, Jonas, Reid, Steven, Larsson, Christer, Eriksson, Pontus, Anderberg, Charlotte, Cortez, Eliane, Saal, Lao H, Orsmark-Pietras, Christina, Cordero, Eugenia, Haller, Bengt Kristian, Häkkinen, Jari, Burvenich, Ingrid J G, Lim, Elgene, Orimo, Akira, Höglund, Mattias, Rydén, Lisa, Moch, Holger, Scott, Andrew M, Eriksson, Ulf, Pietras, Kristian

“…Paracrine signaling networks in the breast cancer microenvironment uncover determinants of hormone receptor status and offer opportunities for therapeutic…”
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