Search Results - "Lanz, A"
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LRRK2 activation in idiopathic Parkinson's disease
Published in Science translational medicine (25-07-2018)“…Missense mutations in leucine-rich repeat kinase 2 (LRRK2) cause familial Parkinson's disease (PD). However, a potential role of wild-type LRRK2 in idiopathic…”
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2
ERG amplification is a secondary recurrent driver event in myeloid malignancy with complex karyotype and TP53 mutations
Published in Genes chromosomes & cancer (01-07-2022)“…ERG is a transcription factor encoded on chromosome 21q22.2 with important roles in hematopoiesis and oncogenesis of prostate cancer. ERG amplification has…”
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Evaluation of TrkB and BDNF transcripts in prefrontal cortex, hippocampus, and striatum from subjects with schizophrenia, bipolar disorder, and major depressive disorder
Published in Neurobiology of disease (01-05-2015)“…Abstract Brain-derived neurotrophic factor (BDNF) signaling is integral to a range of neural functions, including synaptic plasticity and exhibits…”
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MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function
Published in Proceedings of the National Academy of Sciences - PNAS (21-02-2012)“…Schizophrenia is characterized by affective, cognitive, neuromorphological, and molecular abnormalities that may have a neurodevelopmental origin. MicroRNAs…”
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Using Aerosol Light Absorption Measurements for the Quantitative Determination of Wood Burning and Traffic Emission Contributions to Particulate Matter
Published in Environmental science & technology (01-05-2008)“…A source apportionment study was performed for particulate matter in the small village of Roveredo, Switzerland, where more than 70% of the households use wood…”
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Organic aerosol components observed in Northern Hemispheric datasets from Aerosol Mass Spectrometry
Published in Atmospheric chemistry and physics (20-05-2010)“…In this study we compile and present results from the factor analysis of 43 Aerosol Mass Spectrometer (AMS) datasets (27 of the datasets are reanalyzed in this…”
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Source apportionment of submicron organic aerosols at an urban site by factor analytical modelling of aerosol mass spectra
Published in Atmospheric chemistry and physics (01-01-2007)“…Submicron ambient aerosol was characterized in summer 2005 at an urban background site in Zurich, Switzerland, during a three-week measurement campaign. Highly…”
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8
3'Pool-seq: an optimized cost-efficient and scalable method of whole-transcriptome gene expression profiling
Published in BMC genomics (20-01-2020)“…The advent of Next Generation Sequencing has allowed transcriptomes to be profiled with unprecedented accuracy, but the high costs of full-length mRNA…”
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Identification of the Mass Spectral Signature of Organic Aerosols from Wood Burning Emissions
Published in Environmental science & technology (15-08-2007)“…Throughout the winter months, the village of Roveredo, Switzerland, frequently experiences strong temperature inversions that contribute to elevated levels of…”
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10
GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons
Published in PloS one (04-06-2020)“…Deficits in fast-spiking inhibitory interneurons (FSINs) within the dorsolateral prefrontal cortex (dlPFC) are hypothesized to underlie cognitive impairment…”
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CPT and Lorentz symmetry tests with hydrogen using a novel in-beam hyperfine spectroscopy method applicable to antihydrogen experiments
Published in Physics letters. B (01-11-2024)“…We present a Rabi-type measurement of two ground-state hydrogen hyperfine transitions performed in two opposite external magnetic field directions. This puts…”
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Vesicle Origami and the Influence of Cholesterol on Lipid Packing
Published in Langmuir (17-05-2016)“…The artificial phospholipid Pad-PC-Pad was analyzed in 2D (monolayers at the air/water interface) and 3D (aqueous lipid dispersions) systems. In the gel phase,…”
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Inferred Measurements of the Zodiacal Light Absolute Intensity through Fraunhofer Absorption Line Spectroscopy with CIBER
Published in The Astrophysical journal (01-02-2022)“…Abstract Scattered sunlight from the interplanetary dust (IPD) cloud in our solar system presents a serious foreground challenge for spectrophotometric…”
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Measurement of the principal quantum number distribution in a beam of antihydrogen atoms
Published in The European physical journal. D, Atomic, molecular, and optical physics (01-03-2021)“…The ASACUSA (Atomic Spectroscopy And Collisions Using Slow Antiprotons) collaboration plans to measure the ground-state hyperfine splitting of antihydrogen in…”
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15
Characterization of aerosol chemical composition with aerosol mass spectrometry in Central Europe: an overview
Published in Atmospheric chemistry and physics (01-01-2010)“…Real-time measurements of non-refractory submicron aerosols (NR-PM1) were conducted within the greater Alpine region (Switzerland, Germany, Austria, France and…”
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STEP levels are unchanged in pre-frontal cortex and associative striatum in post-mortem human brain samples from subjects with schizophrenia, bipolar disorder and major depressive disorder
Published in PloS one (18-03-2015)“…Increased protein levels of striatal-enriched tyrosine phosphatase (STEP) have recently been reported in postmortem schizophrenic cortex. The present study…”
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Comparison and cross-validation of long-read and short-read target-enrichment sequencing methods to assess AAV vector integration into host genome
Published in Molecular therapy. Methods & clinical development (12-12-2024)“…Evaluation of host integration profiles by adeno-associated virus (AAV) is an important component of de-risking novel AAV gene therapies. Targeted enrichment…”
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Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury
Published in Journal of neuroinflammation (14-05-2018)“…Acute neurological insults caused by infection, systemic inflammation, ischemia, or traumatic injury are often associated with breakdown of the blood-brain…”
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Injection and capture of antiprotons in a Penning–Malmberg trap using a drift tube accelerator and degrader foil
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (01-08-2024)“…The Antiproton Decelerator (AD) at CERN provides antiproton bunches with a kinetic energy of 5.3 MeV. The Extra-Low ENergy Antiproton ring at CERN,…”
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Source Attribution of Submicron Organic Aerosols during Wintertime Inversions by Advanced Factor Analysis of Aerosol Mass Spectra
Published in Environmental science & technology (01-01-2008)“…Real-time measurements of submicrometer aerosol were performed using an Aerodyne aerosol mass spectrometer (AMS) during three weeks at an urban background site…”
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