Search Results - "Lanusse, C.E."

Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole by Devine, C., Brennan, G.P., Lanusse, C.E., Alvarez, L.I., Trudgett, A., Hoey, E., Fairweather, I.

“…An in vivo study in the laboratory rat model has been carried out to monitor morphological changes in adult Fasciola hepatica over a 4-day period resulting…”
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Modified plasma and abomasal disposition of albendazole in nematode-infected sheep by Alvarez, L.I., Sánchez, S.F., Lanusse, C.E.

“…The influence of gastrointestinal nematode infection on the kinetics of albendazole (ABZ) and its metabolites, albendazole sulphoxide (ABZSO) and sulphone…”
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Pharmacologic interaction between oxfendazole and triclabendazole: In vitro biotransformation and systemic exposure in sheep by Viviani, P., Lifschitz, A.L., Luque, S.E., Lloberas, M.M., Maté, M.L., Cardozo, P.A., Lanusse, C.E., Virkel, G.L.

“…The aim of the current work was to evaluate a potential pharmacokinetic interaction between the flukicide triclabendazole (TCBZ) and the broad-spectrum…”
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Enhancement of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica by co-treatment with ketoconazole by Devine, C., Brennan, G.P., Lanusse, C.E., Alvarez, L.I., Trudgett, A., Hoey, E., Fairweather, I.

“…An in vivo study in the laboratory rat model was carried out to monitor morphological changes in adult Fasciola hepatica over a 4-day period resulting from…”
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Altered drug influx/efflux and enhanced metabolic activity in triclabendazole-resistant liver flukes by Alvarez, L I, Solana, H D, Mottier, M L, Virkel, G L, Fairweather, I, Lanusse, C E

“…Triclabendazole (TCBZ) is a halogenated benzimidazole compound that possesses high activity against immature and adult stages of the liver fluke, Fasciola…”
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Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica by Devine, C., Brennan, G. P., Lanusse, C. E., Alvarez, L. I., Trudgett, A., Hoey, E., Fairweather, I.

“…A study has been carried out to investigate whether the action of triclabendazole (TCBZ) against Fasciola hepatica is altered by inhibition of drug metabolism…”
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Erratum to: Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica by Devine, C., Brennan, G. P., Lanusse, C. E., Alvarez, L. I., Trudgett, A., Hoey, E., Fairweather, I.

“…A study has been carried out to investigate whether the action of triclabendazole (TCBZ) against Fasciola hepatica is altered by inhibition of drug metabolism…”
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Milk Excretion of Ivermectin and Moxidectin in Dairy Sheep:  Assessment of Drug Residues during Cheese Elaboration and Ripening Period by Imperiale, Fernanda A, Busetti, Margarita R, Suárez, Victor H, Lanusse, Carlos E

“…Ivermectin (IVM) and moxidectin (MXD) are broad-spectrum endectocide antiparasitic drugs extensively used in food-producing animals. The patterns of IVM and…”
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Transtegumental diffusion of benzimidazole anthelmintics into Moniezia benedeni: correlation with their octanol–water partition coefficients by Mottier, M.L., Alvarez, L.I., Pis, M.A., Lanusse, C.E.

“…The experiments described here report on the correlation between the ex vivo diffusion of different benzimidazole (BZD) anthelmintics into the cestode parasite…”
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Uptake of albendazole and albendazole sulphoxide by Haemonchus contortus and Fasciola hepatica in sheep by Alvarez, L.I, Imperiale, F.A, Sánchez, S.F, Murno, G.A, Lanusse, C.E

“…The pattern of in vivo uptake of albendazole (ABZ) and its major metabolite, ABZ-sulphoxide (ABZSO), by Haemonchus contortus and Fasciola hepatica recovered…”
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Effects of ivermectin and doramectin faecal residues on the invertebrate colonization of cattle dung by Suarez, V.H, Lifschitz, A.L, Sallovitz, J.M, Lanusse, C.E

“…:  The effects of avermectin [ivermectin (IVM) and doramectin (DRM)] faecal residues on dung colonization and degradation by invertebrates were evaluated…”
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Comparative assessment of the access of albendazole, fenbendazole and triclabendazole to Fasciola hepatica: effect of bile in the incubation medium by Alvarez, L I, Mottier, M L, Lanusse, C E

“…The work reported here describes the comparative ability of albendazole (ABZ), fenbendazole (FBZ) and triclabendazole (TCBZ) to penetrate through the tegument…”
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In vivo and ex vivo uptake of albendazole and its sulphoxide metabolite by cestode parasites: relationship with their kinetic behavior in sheep by Alvarez, L.I, Sanchez, S.F, Lanusse, C.E

“…The current experiments correlate the disposition kinetics of albendazole (ABZ) following its intravenous (i.v.) and intraruminal (i.r.) administrations to…”
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Comparative plasma disposition kinetics of albendazole, fenbendazole, oxfendazole and their metabolites in adult sheep by Lanusse, C E, Gascon, L H, Prichard, R K

“…The comparative plasma disposition kinetics of albendazole (ABZ), fenbendazole (FBZ) and oxfendazole (OFZ) following their oral administration (5 mg/kg) to…”
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FASTING-INDUCED CHANGES TO THE PHARMACOKINETIC BEHAVIOUR OF ALBENDAZOLE AND ITS METABOLITES IN CALVES by SÁnchez, S.F., Alvarez, L.I., Lanusse, C.E.

“…The influence of fasting on the bioavailability and disposition kinetics of albendazole (ABZ) and its metabolites in cattle was investigated. ABZ (10 mg/kg)…”
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Ricobendazole kinetics and availability following subcutaneous administration of a novel injectable formulation to calves by Lanusse, C.E., Virkel, G.L., Sanchez, S.F., Alvarez, L.I., Lifschitz, A.L., Imperiale, F., Monfrinotti, A.

“…The plasma and abomasal fluid disposition kinetics of ricobendazole (RBZ) after subcutaneous (SC) administration of novel injectable formulation to calves, and…”
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Metabolism of albendazole and albendazole sulphoxide by ruminal and intestinal fluids of sheep and cattle by Lanusse, C E, Nare, B, Gascon, L H, Prichard, R K

“…1. The metabolism of albendazole (ABZ), albendazole sulphoxide (ABZSO) and albendazole sulphone (ABZSO2) by ruminal, abomasal and ileal fluids of sheep and…”
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Enantioselective binding of albendazole sulphoxide to cytosolic proteins from helminth parasites by SOLANA, H. D, SALLOVITZ, J. M, LANUSSE, C. E, RODRIGUEZ, J. A

“…The pharmacological effect of the active albendazole metabolite, albendazole sulphoxide (ABZSO), depends on its sustained presence at the site of parasite…”
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Influence on the antithyroid compound methimazole on the plasma disposition of fenbendazole and oxfendazole in sheep by Lanusse, C.E, Gascon, L.H, Prichard, R.K

“…The influence of methimazole on the plasma disposition kinetics of fenbendazole, oxfendazole and their metabolites, was investigated in adult sheep. The two…”
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Plasma disposition kinetics of albendazole metabolites in pigs fed different diets by Alvarez, L.I, Saumell, C.A, Sanchez, S.F, Lanusse, C.E

“…The influence of diet on the disposition kinetics of albendazle ( abz) and its metabolites in pigs was investigated. abz was administered orally at 10 mg kg −1…”
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