Search Results - "Lantelme, Erica"

Two Distinct Myeloid Subsets at the Term Human Fetal-Maternal Interface by Costa, Maria Laura, Robinette, Michelle L, Bugatti, Mattia, Longtine, Mark S, Colvin, Bryanne N, Lantelme, Erica, Vermi, William, Colonna, Marco, Nelson, D Michael, Cella, Marina

“…During pregnancy, immune cells infiltrate the placenta at different stages of fetal development. NK cells and macrophages are the most predominant cell types…”
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A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia by Porcedda, Paola, Turinetto, Valentina, Brusco, Alfredo, Cavalieri, Simona, Lantelme, Erica, Orlando, Luca, Ricardi, Umberto, Amoroso, Antonio, Gregori, Dario, Giachino, Claudia

“…Ataxia telangiectasia (A‐T) is a progressive neurodegenerative disease with onset in early childhood, caused by mutations in the ATM (ataxia‐telangiectasia…”
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The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase by Olivero, Martina, Dettori, Daniela, Arena, Sabrina, Zecchin, Davide, Lantelme, Erica, Di Renzo, Maria Flavia

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Impaired elimination of DNA double-strand break-containing lymphocytes in ataxia telangiectasia and Nijmegen breakage syndrome by Porcedda, Paola, Turinetto, Valentina, Lantelme, Erica, Fontanella, Enrico, Chrzanowska, Krystyna, Ragona, Riccardo, De Marchi, Mario, Delia, Domenico, Giachino, Claudia

“…The repair of DNA double-strand breaks is critical for genome integrity and tumor suppression. Here we show that following treatment with the DNA-intercalating…”
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Human CD8 co–receptor is strictly involved in MHC–peptide tetramer–TCR binding and T cell activation by Campanelli, Rita, Palermo, Belinda, Garbelli, Silvia, Mantovani, Stefania, Lucchi, Patrizia, Necker, Antje, Lantelme, Erica, Giachino, Claudia

“…Although there has been extensive analysis on the capacity of MHC–peptide tetramers to bind antigen-specific TCR, there have been comparatively few studies…”
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Diversity of group 1 innate lymphoid cells in human tissues by Jaeger, Natalia, Antonova, Alina Ulezko, Kreisel, Daniel, Roan, Florence, Lantelme, Erica, Ziegler, Steven F., Cella, Marina, Colonna, Marco

“…Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing lymphocytes lacking antigen-specific receptors, which include ILC1s and…”
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Biomolecular condensates regulate cellular electrochemical equilibria by Dai, Yifan, Zhou, Zhengqing, Yu, Wen, Ma, Yuefeng, Kim, Kyeri, Rivera, Nelson, Mohammed, Javid, Lantelme, Erica, Hsu-Kim, Heileen, Chilkoti, Ashutosh, You, Lingchong

“…Control of the electrochemical environment in living cells is typically attributed to ion channels. Here, we show that the formation of biomolecular…”
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Abstract B28: The stress phenotype makes ovarian cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase by Olivero, Martina, Dettori, Daniela, Arena, Sabrina, Zecchin, Davide, Lantelme, Erica, Renzo, Maria Flavia Di

“…CDT2/L2DTL/RAMP is one of the substrate receptors that binds the CRL4 ubiquitin ligase and confers it specificity for a number of substrates, such as CDT1, p21…”
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The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase by Olivero, Martina, Dettori, Daniela, Arena, Sabrina, Zecchin, Davide, Lantelme, Erica, Di Renzo, Maria Flavia

“…CDT2/L2DTL/RAMP is one of the substrate receptors of the Cullin Ring Ubiquitin Ligase 4 that targets for ubiquitin mediated degradation a number of substrates,…”
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Specific Cytotoxic T Lymphocyte Responses Against Melan-A/MART1, Tyrosinase and Gp100 in Vitiligo by the Use of Major Histocompatibility Complex/Peptide Tetramers: the Role of Cellular Immunity in the Etiopathogenesis of Vitiligo by Palermo, Belinda, Campanelli, Rita, Garbelli, Silvia, Mantovani, Stefania, Lantelme, Erica, Brazzelli, Valeria, Ardigó, Marco, Borroni, Giovanni, Martinetti, Miriam, Badulli, Carla, Necker, Antje, Giachino, Claudia

“…Vitiligo is a common skin disease characterized by the presence of well circumscribed, depigmented, milky white macules devoid of identifiable melanocytes…”
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Two-tier analysis of histone H2AX phosphorylation allows the identification of Ataxia Telangiectasia heterozygotes by Porcedda, Paola, Turinetto, Valentina, Orlando, Luca, Lantelme, Erica, Brusco, Alfredo, De Marchi, Mario, Amoroso, Antonio, Ricardi, Umberto, Gregori, Dario, Giachino, Claudia

“…Abstract Background and purpose Ataxia Telangiectasia (A-T) heterozygotes constitute 0.36–1% of the general population. They have a higher risk of developing…”
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A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells by Turinetto, Valentina, Porcedda, Paola, Minieri, Valentina, Orlando, Luca, Lantelme, Erica, Accomasso, Lisa, Amoroso, Antonio, De Marchi, Mario, Zannini, Laura, Delia, Domenico, Giachino, Claudia

“…We have previously shown that whereas T-cells from normal individuals undergo accumulation of p53 and apoptosis when treated with the genotoxic agent…”
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TCR transfer induces TCR-mediated tonic inhibition of RAG genes in human T cells by Orlando, Luca, Accomasso, Lisa, Circosta, Paola, Turinetto, Valentina, Lantelme, Erica, Porcedda, Paola, Minieri, Valentina, Pautasso, Marisa, Willemsen, Ralph A., Cignetti, Alessandro, Giachino, Claudia

“…Induction of the TCR signaling pathway terminates the expression of RAG genes, and a link between this pathway and their transcriptional control is evident…”
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An in vitro model of T cell receptor revision in mature human CD8+ T cells by Lantelme, Erica, Orlando, Luca, Porcedda, Paola, Turinetto, Valentina, De Marchi, Mario, Amoroso, Antonio, Mantovani, Stefania, Giachino, Claudia

“…V(D)J recombination is a mechanism peculiar to the somatic rearrangement of antigen receptor genes. It requires both expression of the RAG-1 and RAG-2…”
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Intranodal injection of semimature monocyte-derived dendritic cells induces T helper type 1 responses to protein neoantigen by Gilliet, Michel, Kleinhans, Martin, Lantelme, Erica, Schadendorf, Dirk, Burg, Günter, Nestle, Frank O.

“…Dendritic cells (DCs) represent the most potent antigen-presenting cells of the immune system capable of initiating primary immune responses to neoantigens…”
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Dominant TCR-alpha requirements for a self antigen recognition in humans by Mantovani, Stefania, Palermo, Belinda, Garbelli, Silvia, Campanelli, Rita, Robustelli Della Cuna, Gioacchino, Gennari, Roberto, Benvenuto, Federica, Lantelme, Erica, Giachino, Claudia

“…TCR-alpha and -beta chains are composed of somatically rearranged V, D, and J germline-encoded gene segments that confer Ag specificity. Recent…”
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A Novel SH3-Containing Human Gene Family Preferentially Expressed in the Central Nervous System by Giachino, Claudia, Lantelme, Erica, Lanzetti, Letizia, Saccone, Salvatore, Valle, Giuliano Della, Migone, Nicola

“…The Src-homology-3 domain (SH3) is an evolutionarily conserved, 50- to 60-amino-acid module carried by intracellular proteins involved in the transduction of…”
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Analysis of Secondary V(D)J Rearrangements in Mature, Peripheral T Cells of Ataxia-Telangiectasia Heterozygotes by Lantelme, Erica, Turinetto, Valentina, Mantovani, Stefania, Marchi, Antonietta, Regazzoni, Silvia, Porcedda, Paola, De Marchi, Mario, Giachino, Claudia

“…Ataxia-telangiectasia (AT) is a rare recessive disease with pleiotropic involvement of the nervous and lymphoid systems. AT heterozygotes have a population…”
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Diverse expansion potential and heterogeneous avidity in tumor‐associated antigen‐specific T lymphocytes from primary melanoma patients by Palermo, Belinda, Campanelli, Rita, Mantovani, Stefania, Lantelme, Erica, Manganoni, Ausilia M., Carella, Graziella, Da Prada, GianAntonio, della Cuna, Gioacchino Robustelli, Romagne, François, Gauthier, Laurent, Necker, Antje, Giachino, Claudia

“…While tumor‐associated antigen (TAA)‐specific CD8+ T lymphocytes have been detected in metastatic melanoma patients, immune response in early disease phases…”
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Increased frequency of RAG‐expressing, CD4+CD3low peripheral T lymphocytes in patients with defective responses to DNA damage by Lantelme, Erica, Mantovani, Stefania, Palermo, Belinda, Campanelli, Rita, Granziero, Luisa, Monafo, Virginia, Giachino, Claudia

“…Accumulating evidence indicates that peripheral lymphocyte variants with altered antigen receptor expression may be capable of expressing…”
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