Search Results - "Lankin, V Z"

PCSK9 Inhibitor causes a decrease in the level of oxidatively modified low-density lipoproteins in patients with coronary artery diseases by Lankin, V Z, Tikhaze, A K, Viigimaa, M, Chazova, I Е

“…We study the dynamics of oxidatively modified low-density lipoprotein (ox-LDL) content in blood plasma, as well as changes in the activity of key antioxidant…”
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Mechanisms of oxidative modification of low density lipoproteins under conditions of oxidative and carbonyl stress by Lankin, V Z, Tikhaze, A K, Kapel'ko, V I, Shepel'kova, G S, Shumaev, K B, Panasenko, O M, Konovalova, G G, Belenkov, Yu N

“…Low-molecular-weight aldehydes (glyoxal, methylglyoxal, 3-deoxyglucosone) generated on autooxidation of glucose under conditions of carbonyl stress react much…”
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Superoxide formation as a result of interaction of L-lysine with dicarbonyl compounds and its possible mechanism by Shumaev, K. B, Gubkina, S. A, Kumskova, E. M, Shepelkova, G. S, Ruuge, E. K, Lankin, V. Z

“…The EPR signal recorded in reaction medium containing L-lysine and methylglyoxal is supposed to come from the anion radical (semidione) of methylglyoxal and…”
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Impact of a cold wave on disease course, hemodynamics, carbohydrate metabolism, and blood rheological properties in cardiac patents by Ageev, F T, Smirnova, M D, Svirida, O N, Fofanova, T V, Vitsenya, M V, Blankova, Z N, Mikhailov, G V, Lankin, V Z, Konovalova, G G, Tikhaze, A K, Ageeva, N V

“…To study the impact of cold waves on disease course, hemodynamics, lipid and carbohydrate metabolisms, oxidative stress, and blood rheological properties in…”
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Blood Plasma Lipoproteids: Oxidizability and Participation in the Transport of Acylhydroperoxy-Derivatives of Phospholipids by Lankin, V. Z., Tikhaze, A. K., Kosach, V. Ya, Doroshchuk, A. D.

“…Oxidatively modified plasma lipoproteins play an important role in the molecular mechanisms of vascular wall damage in atherosclerosis and diabetes mellitus…”
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Clearance of Carbonyl-Modified Low-Density Lipoproteins in Rabbits by Tikhaze, A. K., Domogatsky, S. P., Lankin, V. Z.

“…— The elimination kinetics of carbonyl-modified low density lipoproteins (LDL) from rabbit bloodstream was studied using isolated LDL of rabbits and humans…”
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Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion by Pisarenko, O. I., Lankin, V. Z., Konovalova, G. G., Serebryakova, L. I., Shulzhenko, V. S., Timoshin, A. A., Tskitishvili, O. V., Pelogeykina, Yu. A., Studneva, I. M.

“…This study investigated the effects of peptide apelin-12 (H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, A12) and its novel structural analog (H-(N α…”
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Modification of low-density lipoproteins by low molecular weight carbonyl products of free-radical oxidation of lipids and carbohydrates plays a key role in atherosclerotic lesion of the vascular wall and in endothelial dysfunction by Lankin, V. Z., Tikhaze, A. K., Kosach, V. Ya, Konovalova, G. G., Kudryashova, A. V.

“…The review presents evidence of the participation of low-density lipoproteins (LDL) modified by low molecular weight dicarbonyl compounds formed during…”
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A Possible Mechanism of the Antioxidant Action of Dinitrosyl Iron Complexes by Shumaev, K. B., Kosmachevskaya, O. V., Grachev, D. I., Timoshin, A. A., Topunov, A. F., Lankin, V. Z., Ruuge, E. K.

“…— The antioxidant effect of dinitrosyl iron complexes (DNICs) was studied in various model systems. DNICs with glutathione ligand (DNIC-GS) effectively…”
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Malondialdehyde but Not Methylglyoxal Impairs Insulin Signaling, NO Production, and Endothelial Barrier by Samsonov, M. V., Podkuychenko, N. V., Lankin, V. Z., Vorotnikov, A. V., Shirinsky, V. P.

“…Dyslipidemia and hyperglycemia portray “cause-and-consequence” of type 2 diabetes mellitus (T2DM). They are linked to malondialdehyde (MDA) and methylglyoxal…”
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Influence of dicarbonyls on kinetic characteristics of glutathione peroxidase by Lankin, V. Z., Shumaev, K. B., Tikhaze, A. K., Kurganov, B. I.

“…Se-containing glutathione peroxidase (GSH-Px) is one of the key enzymes of the body’s antioxidant system. The kinetic characteristics of GSH-Px (substrate is…”
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Regulation of free radical processes in healthy volunteers during experimental hyperthermia and in patients with coronary artery disease during summer heat waves by Tikhaze, A. K., Konovalova, G. G., Osyaeva, M. K., Smirnova, M. D., Martynyuk, T. V., Lankin, V. Z.

“…Background . In view of the worsening forecast for global temperature rise worldwide, it seems relevant to study the effects of abnormal heat waves on systemic…”
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Natural Dicarbonyls Inhibit Peroxidase Activity of Peroxiredoxins by Lankin, V. Z., Sharapov, M. G., Goncharov, R. G., Tikhaze, A. K., Novoselov, V. I.

“…It was established that recombinant human peroxiredoxins (Prx1, Prx2, Prx4, and Prx6) inhibit natural dicarbonyls formed during free radical peroxidation of…”
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Anti-Ischemic and Antioxidant Activity of the Pharmacological Agonist of Galanin Receptor GalR2 and Carnosine in In Vitro and In Vivo Model Systems by Serebryakova, L. I., Studneva, I. M., Veselova, O. M., Dobrokhotov, I. V., Konovalova, G. G., Timoshin, A. A., Abramov, A. A., Avdeev, D. V., Sidorova, M. V., Lankin, V. Z., Pisarenko, O. I.

“…Antioxidant and anti-ischemic properties of the pharmacological agonist of galanin receptor GalR2 WTLNSAGYLLGPβAH (Gal) and its C-terminal fragment, dipeptide…”
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Macrophages actively accumulate malonyldialdehyde-modified but not enzymatically oxidized low density lipoprotein by Lankin, V. Z., Tikhaze, A. K., Kumskova, E. M.

“…In this study, we show that low density lipoproteins (LDL) from human blood plasma which was oxidized by animal C-15 lipoxygenase is taken up by cultivated…”
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THE INFLUENCE OF HYPOLIPIDEMIC THERAPY ON THE LEVEL OF MODIFIED LOW DENSITY LIPOPROTEIDES by Lankin, V. Z., Tikhaze, A. K., Konovalova, G. G.

“…Aim. To assess the influence of coronary heart disease patients (CHD) therapy with statins or PCSK9 inhibitors influence on the level of oxidatively modified…”
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The mechanisms of cardiac protection using a synthetic agonist of galanin receptors during chronic administration of doxorubicin by Studneva, Irina M., Veselova, Oksana М., Bahtin, Arthur A., Konovalova, Galina G., Lankin, Vadim Z., Pisarenko, Oleg I.

“…The use of the anticancer drug doxorubicin (Dox) is limited by its cardiotoxic effect. The aim of this work was to study the effect of a new synthetic agonist…”
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Oxidative and carbonyl stress as a factors of the modification of proteins and DNA destruction in diabetes by Lankin, V Z, Tikhaze, A K, Konovalova, G G, Odinokova, O A, Doroshchuk, N A, Chazova, I E

“…To study the oxidative damage of biopolymers (proteins and nucleic acids) in blood of patients with type 2 diabetes mellitus (DM). In the blood of 50 patients…”
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Telomere length as a biomarker of the risk of cardiovascular complications in patients with coronary heart disease by Doroshchuk, N A, Lankin, V Z, Tikhaze, A K, Kheimets, G I, Doroshсhuk, A D, Smirnova, M D, Chazova, I E

“…To study the effect of oxidative stress and telomere length in the chromosomes of blood leukocytes in patients with coronary heart disease (CHD) on the…”
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Oxidative stress in atherosclerosis and diabetes by Lankin, V Z, Lisina, M O, Arzamastseva, N E, Konovalova, G G, Nedosugova, L V, Kaminnyi, A I, Tikhaze, A K, Ageev, F T, Kukharchuk, V V, Belenkov, Yu N

“…We measured the content of lipid peroxides in plasma LDL from patients with chronic CHD not accompanied by hypercholesterolemia; CHD and hypercholesterolemia;…”
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