Search Results - "Lankin, David C"
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Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives
Published in Journal of natural products (Washington, D.C.) (23-03-2018)“…As functional liquid media, natural deep eutectic solvent (NADES) species can dissolve natural or synthetic chemicals of low water solubility. Moreover, the…”
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Importance of purity evaluation and the potential of quantitative ¹H NMR as a purity assay
Published in Journal of medicinal chemistry (26-11-2014)“…In any biomedical and chemical context, a truthful description of chemical constitution requires coverage of both structure and purity. This qualification…”
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3
Accurate and Precise External Calibration Enhances the Versatility of Quantitative NMR (qNMR)
Published in Analytical chemistry (Washington) (09-02-2021)“…Quantitative 1H nuclear magnetic resonance (qHNMR) is a highly regarded analytical methodology for purity determination as it balances metrological rigor,…”
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4
Evolution of Quantitative Measures in NMR: Quantum Mechanical qHNMR Advances Chemical Standardization of a Red Clover (Trifolium pratense) Extract
Published in Journal of natural products (Washington, D.C.) (24-03-2017)“…Chemical standardization, along with morphological and DNA analysis ensures the authenticity and advances the integrity evaluation of botanical preparations…”
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5
Dynamics of the isoflavone metabolome of traditional preparations of Trifolium pratense L
Published in Journal of ethnopharmacology (28-06-2019)“…The flowering tops of Trifolium pratense L., popularly known as red clover, are used in ethnic Western and Traditional Chinese medicine, in a variety of…”
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Preparation of DESIGNER extracts of red clover (Trifolium pratense L.) by centrifugal partition chromatography
Published in Journal of Chromatography A (08-11-2019)“…•Countercurrent separation yields isoflavones-specific Red Clover DESIGNER extracts.•The method produced gram-range quantities, sufficient for in vivo…”
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7
Dissemination of original NMR data enhances reproducibility and integrity in chemical research
Published in Natural product reports (25-08-2016)“…The notion of data transparency is gaining a strong awareness among the scientific community. The availability of raw data is actually regarded as a…”
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8
Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba
Published in Magnetic resonance in chemistry (01-08-2012)“…The complete and unambiguous 1H NMR assignments of ten marker constituents of Ginkgo biloba are described. The comprehensive 1H NMR profiles (fingerprints) of…”
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9
Metabolite Profiling and Classification of DNA-Authenticated Licorice Botanicals
Published in Journal of natural products (Washington, D.C.) (28-08-2015)“…Raw licorice roots represent heterogeneous materials obtained from mainly three Glycyrrhiza species. G. glabra, G. uralensis, and G. inflata exhibit marked…”
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10
Toward Structural Correctness: Aquatolide and the Importance of 1D Proton NMR FID Archiving
Published in Journal of organic chemistry (05-02-2016)“…The revision of the structure of the sesquiterpene aquatolide from a bicyclo[2.2.0]hexane to a bicyclo[2.1.1]hexane structure using compelling NMR data,…”
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11
Orthogonal analytical methods for botanical standardization: Determination of green tea catechins by qNMR and LC–MS/MS
Published in Journal of pharmaceutical and biomedical analysis (01-05-2014)“…The development of analytical methods for parallel characterization of multiple phytoconstituents is essential to advance the quality control of herbal…”
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12
Dynamic Residual Complexity of the Isoliquiritigenin–Liquiritigenin Interconversion During Bioassay
Published in Journal of agricultural and food chemistry (06-03-2013)“…Bioactive components in food plants can undergo dynamic processes that involve multiple chemical species. For example, 2′-hydroxychalcones can readily…”
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13
K‑Targeted Metabolomic Analysis Extends Chemical Subtraction to DESIGNER Extracts: Selective Depletion of Extracts of Hops (Humulus lupulus)
Published in Journal of natural products (Washington, D.C.) (26-12-2014)“…This study introduces a flexible and compound targeted approach to Deplete and Enrich Select Ingredients to Generate Normalized Extract Resources, generating…”
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14
Correction to Importance of Purity Evaluation and the Potential of Quantitative 1H NMR as a Purity Assay
Published in Journal of medicinal chemistry (17-11-2015)Get full text
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15
In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin
Published in Chemico-biological interactions (22-10-2008)“…The lack of a safe and reliable alternative to hormone therapy (HT) for treating menopausal symptoms underscores the need for alternative therapies. The…”
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Structure and Anti-TB Activity of Trachylobanes from the Liverwort Jungermannia exsertifolia ssp. cordifolia
Published in Journal of natural products (Washington, D.C.) (23-04-2010)“…In the critical search for new antituberculosis lead compounds, bryophytes represent a largely untapped resource of chemically diverse structures. From the…”
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Computer‐assisted 1H NMR analysis of the anti‐tuberculosis drug lead ecumicin
Published in Magnetic resonance in chemistry (01-03-2017)Get full text
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18
Low Energy Collision-Induced Dissociation of Azepine Pictet–Spengler Adducts of N ω‑Methylserotonin
Published in Journal of the American Society for Mass Spectrometry (01-02-2023)“…Cimitrypazepines are a class of natural products produced by Pictet–Spengler condensation of N ω-methylserotonin and aldehydes in a manner that produces a…”
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Guanidine Alkaloids and Pictet−Spengler Adducts from Black Cohosh (Cimicifuga racemosa)
Published in Journal of natural products (Washington, D.C.) (27-03-2009)“…As an extension of work on the recently discovered nitrogenous metabolites from Cimicifuga/Actaea species, three new guanidine alkaloids have been isolated and…”
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Essential Parameters for Structural Analysis and Dereplication by 1H NMR Spectroscopy
Published in Journal of natural products (Washington, D.C.) (04-06-2014)“…The present study demonstrates the importance of adequate precision when reporting the δ and J parameters of frequency domain 1H NMR (HNMR) data. Using a…”
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