Search Results - "Lanker, Stefan"
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Neuroimaging to monitor worsening of multiple sclerosis: advances supported by the grant for multiple sclerosis innovation
Published in Frontiers in neurology (01-12-2023)“…Key unmet needs in multiple sclerosis (MS) include detection of early pathology, disability worsening independent of relapses, and accurate monitoring of…”
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Epithelial V-like antigen mediates efficacy of anti-alpha₄ integrin treatment in a mouse model of multiple sclerosis
Published in PloS one (08-08-2013)“…Natalizumab inhibits the transmigration of activated T lymphocytes into the brain and is highly efficacious in multiple sclerosis (MS). However, from a…”
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The ISG15 Isopeptidase UBP43 Is Regulated by Proteolysis via the SCFSkp2 Ubiquitin Ligase
Published in The Journal of biological chemistry (05-11-2004)“…The Skp2 oncoprotein belongs to the family of F-box proteins that function as substrate recognition factors for SCF ( S kp1, c ullin, F -box protein) E3…”
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Cdc53 Targets Phosphorylated G1 Cyclins for Degradation by the Ubiquitin Proteolytic Pathway
Published in Cell (09-08-1996)“…In budding yeast, cell division is initiated in late G1 phase once the Cdc28 cyclin-dependent kinase is activated by the G1 cyclins Cln1, Cln2, and Cln3. The…”
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F-Box Protein Grr1 Interacts with Phosphorylated Targets via the Cationic Surface of Its Leucine-Rich Repeat
Published in Molecular and Cellular Biology (01-04-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transferable Domain in the G1 Cyclin Cln2 Sufficient To Switch Degradation of Sic1 from the E3 Ubiquitin Ligase SCFCdc4 to SCFGrr1
Published in Molecular and Cellular Biology (01-07-2002)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Anti-VLA4-Mediated Inhibition of Humeral Autoimmunity in EAE: Dependence on Epithelial V-Like Antigen Expression (P05.165)
Published in Neurology (12-02-2013)“…Abstract only…”
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Epithelial V-Like Antigen Mediates Efficacy of Anti-Alpha.sub.4 Integrin Treatment in a Mouse Model of Multiple Sclerosis
Published in PloS one (08-08-2013)“…Natalizumab inhibits the transmigration of activated T lymphocytes into the brain and is highly efficacious in multiple sclerosis (MS). However, from a…”
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9
Natalizumab in Patients with Early MS: The STRIVE Study (P3.186)
Published in Neurology (08-04-2014)“…Abstract only…”
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10
Delayed accumulation of the yeast G1 cyclins Cln1 and Cln2 and the F-box protein Grr1 in response to glucose
Published in Yeast (Chichester, England) (01-05-2007)“…The ability to integrate nutrient availability into cell cycle regulation is critical for the viability of organisms. The Saccharomyces cerevisiae ubiquitin…”
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Delayed accumulation of the yeast G1 cyclins Cln1 and Cln2 and the F‐box protein Grr1 in response to glucose
Published in Yeast (Chichester, England) (01-05-2007)“…The ability to integrate nutrient availability into cell cycle regulation is critical for the viability of organisms. The Saccharomyces cerevisiae ubiquitin…”
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12
Delayed accumulation of the yeast G 1 cyclins Cln1 and Cln2 and the F‐box protein Grr1 in response to glucose
Published in Yeast (Chichester, England) (01-05-2007)“…The ability to integrate nutrient availability into cell cycle regulation is critical for the viability of organisms. The Saccharomyces cerevisiae ubiquitin…”
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13
Integrin/Chemokine Receptor Interactions in the Pathogenesis of Experimental Autoimmune Encephalomyelitis
Published in Journal of neuroimmune pharmacology (01-06-2014)“…Excessive infiltration of leukocytes and the elaboration of inflammatory cytokines are believed to be responsible for the observed damage to neurons and…”
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Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation
Published in Science (American Association for the Advancement of Science) (15-03-1996)“…Cyclins regulate the major cell cycle transitions in eukaryotes through association with cyclin-dependent protein kinases (CDKs). In yeast, G1 cyclins are…”
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15
SCF Grr1-Mediated Ubiquitination of Gis4 Modulates Glucose Response in Yeast
Published in Journal of molecular biology (2005)“…The F box protein Grr1 is the substrate specificity-determinant of the SCF Grr1 E3 ubiquitin ligase complex. Genetic analyses of Grr1 mutants have implicated…”
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Interferon-beta-1a treatment increases CD56 bright natural killer cells and CD4+CD25+ Foxp3 expression in subjects with multiple sclerosis
Published in Journal of neuroimmunology (2009)“…Disease modifying effects of interferon (IFN)-β therapy in patients with multiple sclerosis (MS) may be mediated in part through enhanced immunoregulation by…”
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17
Interferon-beta-1a treatment increases CD56bright natural killer cells and CD4+CD25+ Foxp3 expression in subjects with multiple sclerosis
Published in Journal of neuroimmunology (30-10-2009)“…Abstract Disease modifying effects of interferon (IFN)-β therapy in patients with multiple sclerosis (MS) may be mediated in part through enhanced…”
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SCFGrr1-mediated ubiquitination of Gis4 modulates glucose response in yeast
Published in Journal of molecular biology (17-06-2005)“…The F box protein Grr1 is the substrate specificity-determinant of the SCF(Grr1) E3 ubiquitin ligase complex. Genetic analyses of Grr1 mutants have implicated…”
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The ISG15 Isopeptidase UBP43 Is Regulated by Proteolysis via the SCF super(Skp2) Ubiquitin Ligase
Published in The Journal of biological chemistry (05-11-2004)“…The Skp2 oncoprotein belongs to the family of F-box proteins that function as substrate recognition factors for SCF (Skp1, cullin, F-box protein) E3…”
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Yeast G1 cyclins are unstable in G1 phase
Published in Nature (London) (03-09-1998)“…In most eukaryotes, commitment to cell division occurs in late G1 phase at an event called Start in the yeast Saccharomyces cerevisiae, and called the…”
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