Search Results - "Lania, L"

Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway by Ambrosio, S, Saccà, C D, Amente, S, Paladino, S, Lania, L, Majello, B

“…Autophagy is a physiological process, important for recycling of macromolecules and maintenance of cellular homeostasis. Defective autophagy is associated with…”
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LSD1-mediated demethylation of histone H3 lysine 4 triggers Myc-induced transcription by Amente, S, Bertoni, A, Morano, A, Lania, L, Avvedimento, E V, Majello, B

“…Myc is a transcription factor that significantly contributes to cancer progression by modulating the expression of important genes through binding to a DNA…”
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Transcriptional regulation by the Sp family proteins by Lania, Luigi, Majello, Barbara, de Luca, Pasquale

“…Spl is one of the very first cellular transcription factors to be identified and cloned in virtue of its binding to a Grich motif in the SV40 early promoter…”
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Increased HEXIM1 expression during erythroleukemia and neuroblastoma cell differentiation by Turano, Mimmo, Napolitano, Giuliana, Dulac, Cyprien, Majello, Barbara, Bensaude, Olivier, Lania, Luigi

“…The HEXIM1 protein, in association with 7SK snRNA, binds and inhibits the kinase activity of P‐TEFb (CDK9/cyclin T). P‐TEFb activity is crucial for efficient…”
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Krüppel-Associated Box-Mediated Repression of RNA Polymerase II Promoters is Influenced by the Arrangement of Basal Promoter Elements by Pengue, Gina, Lania, Luigi

“…The evolutionarily conserved Krüppel-associated box (KRAB) is present in the N-terminal regions of more than one-third of all Krüppel-class zinc finger…”
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Recruitment of human TBP selectively activates RNA polymerase II TATA-dependent promoters by Majello, B, Napolitano, G, De Luca, P, Lania, L

“…An increasing body of evidence suggests that eukaryotic activators stimulate polymerase II transcription by facilitating the assembly of the functional basal…”
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Transcriptional silencing of human immunodeficiency virus type 1 long terminal repeat-driven gene expression by the Krüppel-associated box repressor domain targeted to the transactivating response element by Pengue, G, Caputo, A, Rossi, C, Barbanti-Brodano, G, Lania, L

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Bellini duct carcinoma. A clinical and in vitro study by Cavazzana, A O, Prayer-Galetti, T, Tirabosco, R, Macciomei, M C, Stella, M, Lania, L, Cannada-Bartoli, P, Spagnoli, L G, Passerini-Glazel, G, Pagano, F

“…Bellini duct carcinoma (BDC) is a rare and highly aggressive renal tumor whose histogenesis is still a matter of debate although a putative origin from…”
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Status and expression of the p16INK4 gene in human thyroid tumors and thyroid‐tumor cell lines by Calabrò, Viola, Strazzullo, Maria, La Mantia, Girolama, Fedele, Monica, Paulin, Christian, Fusco, Alfredo, Lania, Luigi

“…The p16INK4 tumor‐suppressor gene (also known as CDKN2, CDK41 and MTSI) encodes a negative regulator of the cell cycle. This gene, located in 9p21, is mutated…”
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Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor by Michels, Annemieke A, Fraldi, Alessandro, Li, Qintong, Adamson, Todd E, Bonnet, François, Nguyen, Van Trung, Sedore, Stanley C, Price, Jason P, Price, David H, Lania, Luigi, Bensaude, Olivier

“…The positive transcription elongation factor b (P‐TEFb) plays a pivotal role in productive elongation of nascent RNA molecules by RNA polymerase II. Core…”
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MAQ1 and 7SK RNA Interact with CDK9/Cyclin T Complexes in a Transcription-Dependent Manner by Michels, Annemieke A., Nguyen, Van Trung, Fraldi, Alessandro, Labas, Valérie, Edwards, Mia, Bonnet, François, Lania, Luigi, Bensaude, Olivier

“…AUTHOR'S CORRECTION ( vol. 23 , p. 9405 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Myc and PI3K/AKT signaling cooperatively repress FOXO3a-dependent PUMA and GADD45a gene expression by Amente, S., Zhang, J., Lavadera, M. L., Lania, L., Avvedimento, E. V., Majello, B.

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Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation by Amente, Stefano, Napolitano, Giuliana, Licciardo, Paolo, Monti, Maria, Pucci, Piero, Lania, Luigi, Majello, Barbara

“…FCP1, a phosphatase specific of the carboxyl-terminal-domain of the large subunit of the RNA polymerase II (RNAPII), stimulates transcription elongation and it…”
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Sp3 Is a Bifunctional Transcription Regulator with Modular Independent Activation and Repression Domains by Majello, Barbara, De Luca, Pasquale, Lania, Luigi

“…Sp3 is a member of the Sp family of transcription factors and binds to DNA with affinity and specificity comparable to that of Sp1. We demonstrate that Sp3 is…”
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Class A helix-loop-helix proteins are positive regulators of several cyclin-dependent kinase inhibitors' promoter activity and negatively affect cell growth by Pagliuca, A, Gallo, P, De Luca, P, Lania, L

“…The class A of basic helix-loop-helix (bHLH) proteins are ubiquitously expressed transcription factors playing a pivotal role in the regulation of cell growth…”
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Loss of functional large T-antigen and free viral genomes from cells transformed in vitro by polyoma virus after passage in vivo as tumor cells by Lania, L, Hayday, A, Fried, M

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Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1 by Majello, B, De Luca, P, Hagen, G, Suske, G, Lania, L

“…Recently, a family of transcription factors structurally related to Sp1 has been described; thus, more than one activator may bind to the GC boxes present in a…”
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Polyomavirus mutation that confers a cell-specific cis advantage for viral DNA replication by DE SIMONE, V, LA MANTIA, G, LANIA, L, AMATI, P

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Active viral genes in transformed cells lie close to the nuclear cage by Cook, P.R., Lang, J., Hayday, A., Lania, L., Fried, M., Chiswell, D.J., Wyke, J.A.

“…Nuclear DNA is looped by attachment to a matrix or cage. Using nine different lines transformed by polyoma or avian sarcoma virus, we have mapped viral…”
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Isolation of Cellular DNA Sequences That Allow Expression of Adjacent Genes by Fried, Mike, Griffiths, Moira, Davies, Brendan, Bjursell, Gunnar, La Mantia, Girolama, Lania, Luigi

“…We have employed a strategy for the isolation and identification of cellular control (expression) sequences dependent on their ability to confer expression on…”
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