Search Results - "Langrana, Noshir A."

Neural lineage differentiation of embryonic stem cells within alginate microbeads by Li, Lulu, Davidovich, Alexander E, Schloss, Jennifer M, Chippada, Uday, Schloss, Rene R, Langrana, Noshir A, Yarmush, Martin L

“…Abstract Cell replacement therapies, using renewable stem cell sources, hold tremendous potential to treat a wide range of degenerative diseases. Although many…”
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The relationship between fibroblast growth and the dynamic stiffnesses of a DNA crosslinked hydrogel by Jiang, Frank X, Yurke, Bernard, Schloss, Rene S, Firestein, Bonnie L, Langrana, Noshir A

“…Abstract The microenvironment of cells is dynamic and undergoes remodeling with time. This is evident in development, aging, pathological processes, and at…”
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Mechanical properties of a reversible, DNA-crosslinked polyacrylamide hydrogel by Lin, David C, Yurke, Bernard, Langrana, Noshir A

“…Mechanical properties of a polyacrylamide gel with reversible DNA crosslinks are presented. In this system, three DNA strands replace traditional chemical…”
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Effect of dynamic stiffness of the substrates on neurite outgrowth by using a DNA-crosslinked hydrogel by Jiang, Frank Xue, Yurke, Bernard, Schloss, Rene S, Firestein, Bonnie L, Langrana, Noshir A

“…Central nervous system tissues, like other tissue types, undergo constant remodeling, which potentially leads to changes in their mechanical stiffness…”
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Probing Mechanical Adaptation of Neurite Outgrowth on a Hydrogel Material Using Atomic Force Microscopy by Jiang, Frank Xue, Lin, David C, Horkay, Ferenc, Langrana, Noshir A

“…In this study, we describe the design and initial results of probing mechanical adaptation of neurite growth of lightly fixed neurons on a hydrogel substrate…”
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Fibroblast Morphology on Dynamic Softening of Hydrogels by Previtera, Michelle L., Trout, Kevin L., Verma, Devendra, Chippada, Uday, Schloss, Rene S., Langrana, Noshir A.

“…Despite cellular environments having dynamic characteristics, many laboratories utilized static polyacrylamide hydrogels to study the ECM–cell relationship. To…”
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Chitosan-polygalacturonic acid complex dressing improves diabetic wound healing and hair growth in diabetic mice by Mistry, Priya, Kumar, Suneel, Schloss, Rene S., Berthiaume, Francois, Langrana, Noshir A.

“…Chronic skin wounds decrease the quality of life of millions of diabetic patients worldwide. Chitosan has previously been shown to possess hemostatic…”
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Functional Modulation of ES-Derived Hepatocyte Lineage Cells via Substrate Compliance Alteration by Li, Lulu, Sharma, Nripen, Chippada, Uday, Jiang, Xue, Schloss, Rene, Yarmush, Martin L., Langrana, Noshir A.

“…Pluripotent embryonic stem cells represent a promising renewable cell source to generate a variety of differentiated cell types including hepatocyte lineage…”
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Simultaneous determination of Young's modulus, shear modulus, and Poisson's ratio of soft hydrogels by Chippada, Uday, Yurke, Bernard, Langrana, Noshir A.

“…Besides biological and chemical cues, cellular behavior has been found to be affected by mechanical cues such as traction forces, surface topology, and in…”
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Neurite Outgrowth on a DNA Crosslinked Hydrogel with Tunable Stiffnesses by Jiang, Frank Xue, Yurke, Bernard, Firestein, Bonnie L., Langrana, Noshir A.

“…Mechanical cues arising from extracellular matrices greatly affect cellular properties, and hence, are of significance in designing biomaterials. In this…”
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Structural quality of parts processed by fused deposition by Agarwala, Mukesh K., Jamalabad, Vikram R., Langrana, Noshir A., Safari, Ahmad, Whalen, Philip J., Danforth, Stephen C.

“…Commercial solid freeform fabrication (SFF) systems, which have been developed for fabrication of wax and polymer parts for form and fit and secondary…”
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Validation of a musculoskeletal model of wheelchair propulsion and its application to minimizing shoulder joint forces by Dubowsky, Sarah R, Rasmussen, John, Sisto, Sue Ann, Langrana, Noshir A

“…Abstract The majority of manual wheelchair users (MWUs) will inevitably develop some degree of shoulder pain over time. Previous research has suggested a link…”
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The Effects of Substrate Elastic Modulus on Neural Precursor Cell Behavior by Previtera, Michelle L., Hui, Mason, Verma, Devendra, Shahin, Abdelhamid J., Schloss, Rene, Langrana, Noshir A.

“…The spinal cord has a limited capacity to self-repair. After injury, endogenous stem cells are activated and migrate, proliferate, and differentiate into glial…”
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Regulation of Dendrite Arborization by Substrate Stiffness is Mediated by Glutamate Receptors by Previtera, Michelle L, Langhammer, Christopher G, Langrana, Noshir A, Firestein, Bonnie L

“…Brain injury or disease can initiate changes in local or global stiffness of brain tissue. While stiffness of the extracellular environment is known to affect…”
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Comparison of kinematics, kinetics, and EMG throughout wheelchair propulsion in able-bodied and persons with paraplegia: an integrative approach by Dubowsky, Sarah R, Sisto, Sue Ann, Langrana, Noshir A

“…A systematic integrated data collection and analysis of kinematic, kinetic, and electromyography (EMG) data allow for the comparison of differences in…”
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Preparation of DNA-crosslinked polyacrylamide hydrogels by Previtera, Michelle L, Langrana, Noshir A

“…Mechanobiology is an emerging scientific area that addresses the critical role of physical cues in directing cell morphology and function. For example, the…”
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A nonintrusive method of measuring the local mechanical properties of soft hydrogels using magnetic microneedles by Chippada, Uday, Yurke, Bernard, Georges, Penelope C, Langrana, Noshir A

“…Soft hydrogels serving as substrates for cell attachment are used to culture many types of cells. The mechanical properties of these gels influence cell…”
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A review of spinal fusion for degenerative disc disease: need for alternative treatment approach of disc arthroplasty? by Lee, Casey K., Langrana, Noshir A.

“…This article reviews the history of spinal fusion. The most common indication for fusion may be painful disc degeneration although the exact determination of…”
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Biomechanical effects of unipedicular vertebroplasty on intact vertebrae by Higgins, Kathryn B, Harten, Robert D, Langrana, Noshir A, Reiter, Mitchell F

“…To assess the biomechanical effects of unipedicular vertebroplasty on nonfractured vertebrae. To evaluate the potential benefits of vertebroplasty as a…”
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Role of ligaments and facets in lumbar spinal stability by Sharma, M, Langrana, N A, Rodriguez, J

“…The issue of segmental stability using finite element analysis was studied. Effect of ligament and facet (total and partial) removal and their geometry on…”
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