Search Results - "Langowski, J."

Polymer chain models of DNA and chromatin by Langowski, J

“…Many properties of the genome in the cell nucleus can be understood by modeling DNA and chromatin as a flexible polymer chain. This article introduces into…”
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In the soft grip of nature by Langowski, J K A, Sharma, P, Shoushtari, A Leylavi

“…Biological grippers can inspire the development of a new class of versatile soft grippers in agrorobotics and beyond…”
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Protein Disorder Prevails under Crowded Conditions by Szasz, Cs, Alexa, A, Toth, K, Rakacs, M, Langowski, J, Tompa, P

“…Crowding caused by the high concentrations of macromolecules in the living cell changes chemical equilibria, thus promoting aggregation and folding reactions…”
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Brownian Dynamics Simulation of DNA Unrolling from the Nucleosome by Wocjan, T, Klenin, K, Langowski, J

“…Nucleosomes organize chromatin in eukaryotic cells at the lowest scale by wrapping the DNA double helix around a histone octamer. The mechanism by which this…”
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Assessing the Flexibility of Intermediate Filaments by Atomic Force Microscopy by Mücke, N., Kreplak, L., Kirmse, R., Wedig, T., Herrmann, H., Aebi, U., Langowski, J.

“…Eukaryotic cells contain three cytoskeletal filament systems that exhibit very distinct assembly properties, supramolecular architectures, dynamic behaviour…”
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Protein–Protein Interactions Determined by Fluorescence Correlation Spectroscopy by Langowski, J.

“…Fluorescence correlation spectroscopy (FCS) is an emerging technique where the interaction between biomolecules is detected through their correlated motion. It…”
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Intra-tumoral immune cell mobilization and anti-tumor activity after treatment with the engineered cytokine NKTR-214 in multiple preclinical mouse tumor models by Charych, D, Hennessy, M, Langowski, J, Dixit, V, Rubas, W, Hoch, U, Pena, R, Quach, P, Doberstein, S.K, Zaleveky, J

“…Background: NKTR-214 is an immune-stimulatory cytokine designed to provide a sustained CD122-biased activation signal through the heterodimeric lL2 receptor…”
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Anomalous diffusion in the presence of mobile obstacles by Wedemeier, A, Merlitz, H, Langowski, J

“…In this letter a lattice model for the diffusional transport of binding proteins in a dynamic chromatin fiber network is proposed. Dynamic dense networks are…”
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DNA bending potentials for loop-mediated nucleosome repositioning by Biswas, M., Wocjan, T., Langowski, J., Smith, J. C.

“…Nucleosome repositioning is a fundamental process in gene function. DNA elasticity is a key element of loop-mediated nucleosome repositioning. Two analytical…”
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Note: multiplexed multiple-tau auto- and cross-correlators on a single field programmable gate array by Mocsár, G, Kreith, B, Buchholz, J, Krieger, J W, Langowski, J, Vámosi, G

“…We introduce a new multiple-tau hardware correlator design for computing fluorescence correlation functions (CFs) in real time. Use of hardware resources is…”
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Mad dogs, englishmen and apoptosis: The role of cell death in UV-induced skin cancer by GUZMAN, E, LANGOWSKI, J. L, OWEN-SCHAUB, L

“…Apoptosis plays a critical role in the development and progression of ultraviolet-induced skin cancers. In particular, Fas and Fas ligand (FasL) interactions…”
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Escherichia coli low-copy-number plasmid R1 centromere parC forms a U-shaped complex with its binding protein ParR by Hoischen, C, Bussiek, M, Langowski, J, Diekmann, S

“…The Escherichia coli low-copy-number plasmid R1 contains a segregation machinery composed of parC, ParR and parM. The R1 centromere-like site parC contains two…”
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Mechanism of Hairpin-Duplex Conversion for the HIV-1 Dimerization Initiation Site by Bernacchi, Serena, Ennifar, Eric, Tóth, Katalin, Walter, Philippe, Langowski, Jörg, Dumas, Philippe

“…We have used the dimerization initiation site of HIV-1 genomic RNA as a model to investigate hairpin-duplex interconversion with a combination of fluorescence,…”
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Knowledge-Based Expert Systems for Toxicity and Metabolism Prediction: DEREK, StAR and METEOR by Greene, N., Judson, P. N., Langowski, J. J., Marchant, C. A.

“…It has long been recognised that the ability to predict the metabolic fate of a chemical substance and the potential toxicity of either the parent compound or…”
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Computer prediction of possible toxic action from chemical structure: an update on the DEREK system by Ridings, J.E., Barratt, M.D., Cary, R., Earnshaw, C.G., Eggington, C.E., Ellis, M.K., Judson, P.N., Langowski, J.J., Marchant, C.A., Payne, M.P., Watson, W.P., Yih, T.D.

“…Computer-based assessment of potential toxicity has become increasingly popular in recent years. The knowledgebase system DEREK is developed under the guidance…”
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Characterization of simian virus 40 on its infectious entry pathway in cells using fluorescence correlation spectroscopy by Bernacchi, S, Mueller, G, Langowski, J, Waldeck, W

“…SV40 (simian virus 40) is a double-stranded DNA virus and is strongly oncogenic in experimental animals. SV40 enters cells by atypical endocytosis mediated by…”
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Trajectory of Nucleosomal Linker DNA Studied by Fluorescence Resonance Energy Transfer by Tóth, Katalin, Brun, Nathalie, Langowski, Jörg

“…While the structure of the nucleosome core is known in atomic detail, the precise geometry of the DNA beyond the core particle is still unknown. We have used…”
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Brownian dynamics simulations of supercoiled DNA with bent sequences by Chirico, G., Langowski, J.

“…The recently presented Brownian dynamics model for superhelical DNA is extended to include local curvature of the DNA helix axis. Here we analyze the effect of…”
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Superhelix dimensions of a 1868 base pair plasmid determined by scanning force microscopy in air and in aqueous solution by Rippe, Karsten, Mücke, Norbert, Langowski, Jörg

“…We have used scanning force microscopy (SFM) to study the conformation of a 1868 base pair plasmid (p1868) in its open circular form and at a superhelical…”
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Abrogation of delayed type hypersensitivity response to Candida albicans produced by a molecular mimic of phosphorylated prolactin by Guzmán, E.A., Chen, Y.-H., Langowski, J.L., De Guzman, A., Lo, H.-L., Walter, B., Muller, H.K., Walker, A.M., Owen, L.B.

“…The effects of two major forms of prolactin (PRL) were examined on delayed type hypersensitivity (DTH) responses to Candida albicans. Unmodified PRL (U-PRL)…”
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