Search Results - "Langley, R.W."

Comparison of diphenhydramine and modafinil on arousal and autonomic functions in healthy volunteers by Hou, R.H., Langley, R.W., Szabadi, E., Bradshaw, C.M.

“…Arousal is regulated by the interplay between wakefulness- and sleep-promoting nuclei. Major wakefulness-promoting nuclei are the histaminergic tuberomamillary…”
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Comparison of the effects of 2,5-dimethoxy-4-iodoamphetamine and D-amphetamine on the ability of rats to discriminate the durations and intensities of light stimuli by Hampson, C.L, Body, S, den Boon, F.S, Cheung, T.H.C, Bezzina, G, Langley, R.W, Fone, K.C.F, Bradshaw, C.M, Szabadi, E

“…Ratsʼ ability to discriminate durations is disrupted by the monoamine-releasing agent D-amphetamine and the 5-HT2 receptor agonist…”
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Effects of lesions of the nucleus accumbens core on inter-temporal choice: Further observations with an adjusting-delay procedure by da Costa Araújo, S., Body, S., Hampson, C.L., Langley, R.W., Deakin, J.F.W., Anderson, I.M., Bradshaw, C.M., Szabadi, E.

“…Previous experiments using progressive-delay schedules showed that destruction of the nucleus accumbens core (AcbC) altered rats’ choice between food…”
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Comparison of pramipexole and modafinil on arousal, autonomic, and endocrine functions in healthy volunteers by Samuels, E. R., Hou, R. H., Langley, R. W., Szabadi, E., Bradshaw, C. M.

“…The noradrenergic locus coeruleus is a major wakefulness-promoting nucleus of the brain, which is also involved in the regulation of autonomic and endocrine…”
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Corrigendum to “Effects of lesions of the nucleus accumbens core on inter-temporal choice: Further observations with an adjusting-delay procedure” [Behav. Brain Res. 202 (2009) 272–277] by da Costa Araújo, S., Body, S., Hampson, C.L., Langley, R.W., Deakin, J.F.W., Anderson, I.M., Bradshaw, C.M., Szabadi, E.

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Diazepam suppresses the acquisition but not the expression of 'fear-potentiation' of the acoustic startle response in man by SCAIFE, J. C, LANGLEY, R. W, BRADSHAW, C. M, SZABADI, E

“…Sudden auditory stimuli elicit a short-latency muscular response (acoustic startle response) which is enhanced during presentation of a Pavlovian conditioned…”
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Sensitivity of late-latency auditory and somatosensory evoked potentials to threat of electric shock and the sedative drugs diazepam and diphenhydramine in human volunteers by Scaife, J. C., Groves, J., Langley, R. W., Bradshaw, C. M., Szabadi, E.

“…Late-latency auditory and somatosensory evoked potentials are sensitive to some centrally acting drugs and to certain psychological interventions. In this…”
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Effects of lorazepam on fear-potentiated startle responses in man by Graham, S. J., Scaife, J. C., Langley, R. W., Bradshaw, C. M., Szabadi, E., Xi, L., Crumley, T., Calder, N., Gottesdiener, K., Wagner, J. A.

“…Sudden intense sensory stimuli elicit a cascade of involuntary responses, including a short-latency skeletal muscular response (‘eyeblink startle response’)…”
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Diazepam-induced disruption of classically-conditioned fear-potentiation of late-latency auditory evoked potentials is prevented by flumazenil given before, but not after, CS/US pairing by Scaife, J. C., Hou, R. H., Samuels, E. R., Baqui, F., Langley, R. W., Bradshaw, C. M., Szabadi, E.

“…Classical fear conditioning involves pairing a neutral conditional stimulus (CS) with an aversive unconditional stimulus (US). Subsequent presentation of the…”
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Effects of clonidine and diazepam on the acoustic startle response and on its inhibition by 'prepulses' in man by Abduljawad, K A, Langley, R W, Bradshaw, C M, Szabadi, E

“…This experiment examined the effects of two sedative/anxiolytic drugs, diazepam and clonidine, on the eyeblink component of the acoustic startle response in…”
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Effects of bromocriptine and haloperidol on prepulse inhibition of the acoustic startle response in man by Abduljawad, K A, Langley, R W, Bradshaw, C M, Szabadi, E

“…Experiments with animals have shown that D2 dopamine (DA) receptors are involved in prepulse inhibition of the acoustic startle reflex (suppression of the…”
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Cumulative and noncumulative dose-response curves to noradrenaline on the dorsal hand vein by Abdelmawla, A.H., Langley, R.W., Szabadi, E., Bradshaw, C.M.

“…Cumulative and noncumulative dose-response curves to noradrenaline were compared in the human dorsal hand vein (DHV), using the DHV compliance technique. This…”
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The opposite effects of amitriptyline on noradrenaline- and methoxamine-evoked venoconstriction in man by Abdelmawla, A H, Langley, R W, Szabadi, E, Bradshaw, C M

“…The effects of a single oral dose (100 mg) of amitriptyline on noradrenaline- and methoxamine-evoked venoconstriction were compared, using the dorsal hand vein…”
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Distribution effectiveness factors for the human bone marrow system exposed to space protons by Billings, M P, Langley, R W

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