Search Results - "Langley, E. M."

Importance of HOX genes in normal prostate gland formation, prostate cancer development and its early detection by Javed, Saqib, Langley, Stephen E.M.

“…The aims of this paper were to review the published literature on the role of HOX genes in the development of the normal prostate gland and in prostate cancer…”
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A prospective, randomized pilot study evaluating the effects of metformin and lifestyle intervention on patients with prostate cancer receiving androgen deprivation therapy by Nobes, Jenny P., Langley, Stephen E.M., Klopper, Tanya, Russell‐Jones, David, Laing, Robert W.

“…Study Type – Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Men with prostate cancer have higher rates of…”
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Low‐dose‐rate brachytherapy for prostate cancer stands the test of time – the Swiss experience by Langley, Stephen E.M.

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The role of transperineal template prostate biopsies in restaging men with prostate cancer managed by active surveillance by Ayres, Benjamin E., Montgomery, Bruce S.I., Barber, Neil J., Pereira, Nicola, Langley, Stephen E.M., Denham, Philippa, Bott, Simon R.J.

“…Study Type – Diagnostic (exploratory cohort) Level of Evidence 3b What's known on the subject? and What does the study add? The optimal method of active…”
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Modified transurethral resection of the prostate (TURP) for men with moderate lower urinary tract symptoms (LUTS) before brachytherapy is safe and feasible by Brousil, Philip, Hussain, Muddassar, Lynch, Mark, Laing, Robert W., Langley, Stephen E.M.

“…ObjectiveTo report the urinary toxicity outcomes for patients at greater risk of voiding symptoms and retention who received a modified limited transurethral…”
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4D Brachytherapy, a novel real‐time prostate brachytherapy technique using stranded and loose seeds by Langley, Stephen E. M., Laing, Robert W.

“…What's known on the subject? and What does the study add? There are a number of techniques used successfully to perform brachytherapy, including 2‐stage…”
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Extensive transperineal template biopsies of prostate: Modified technique and results by Bott, Simon R.J., Henderson, Alastair, Halls, James E., Montgomery, Bruce S.I., Laing, Robert, Langley, Stephen E.M.

“…To describe the modified technique and results of extensive transperineal template prostate biopsies in men with a high risk of prostate cancer in whom…”
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Long‐term toxicity and quality of life up to 10 years after low‐dose rate brachytherapy for prostate cancer by Emara, Amr M., Chadwick, Eliot, Nobes, Jenny P., Abdelbaky, Ather Mohamed, Laing, Robert W., Langley, Stephen E.M.

“…Study Type – Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? •  Prostate BXT is an established treatment…”
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A Randomized Controlled Trial Investigating the Effects of Celecoxib in Patients with Localized Prostate Cancer by SOORIAKUMARAN, Prasanna, COLEY, Helen M, FOX, Stephen B, MACANAS-PIRARD, Patricia, LOVELL, David P, HENDERSON, Alastair, EDEN, Chris G, MILLER, Paul D, LANGLEY, Stephen E. M, LAING, Robert W

“…Cyclooxygenase-2 (COX-2) is associated with tumour promotion, inhibition of apoptosis, angiogenesis and metastasis. Celecoxib, a selective COX-2 inhibitor was…”
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Long‐term oncological outcomes and toxicity in 597 men aged ≤60 years at time of low‐dose‐rate brachytherapy for localised prostate cancer by Langley, Stephen E. M., Soares, Ricardo, Uribe, Jennifer, Uribe‐Lewis, Santiago, Money‐Kyrle, Julian, Perna, Carla, Khaksar, Sara, Laing, Robert

“…Objectives To report oncological and functional outcomes of men treated with low‐dose‐rate (LDR) prostate brachytherapy aged ≤60 years at time of treatment…”
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Venous thromboembolism and cyproterone acetate in men with prostate cancer: a study using the General Practice Research Database by Seaman, Helen E., Langley, Stephen E.M., Farmer, Richard D.T., De Vries, Corinne S.

“…OBJECTIVE To evaluate the risk of venous thromboembolism (VTE) associated with the use of cyproterone acetate (CPA) amongst men with prostate cancer. PATIENTS…”
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State-of-the-art: prostate LDR brachytherapy by Voulgaris, S, Nobes, J P, Laing, R W, Langley, S E M

“…This article on low dose rate (LDR) prostate brachytherapy reviews long-term results, patient selection and quality of life issues. Mature results from the…”
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Investigating the associations of mucosal P2Y6 receptor expression and urinary ATP and ADP concentrations, with symptoms of overactive bladder by Firouzmand, Sepinoud, Ajori, Ladan, Towse, Jonathan, Allameh, Farzad, Najafi, Saman, Javed, Saqib, John, Babbin, Langley, Stephen E. M., Fry, Christopher H., Young, John S.

“…Aim To characterize purinergic signaling in overactive bladder (OAB). Methods Mucosal biopsies were taken by flexible cystoscopy from patients with storage…”
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Biochemical relapse-free survival in 400 patients treated with I-125 prostate brachytherapy: the Guildford experience by Nobes, J P, Wells, I G, Khaksar, S J, Money-Kyrle, J F, Laing, R W, Langley, S E M

“…A total of 1200 patients had undergone I-125 prostate brachytherapy (BXT) in our centre. We present prospective outcome data for the first 400 treated…”
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Are prostatic biopsies necessary in men aged ≥80 years? by Bott, Simon R.J., Foley, Charlotte L., Bull, Matthew D., Reddy, C.C. Jeevan, Freeman, Alex, Montgomery, Bruce S.I., Langley, Stephen E.M.

“…OBJECTIVE To examine whether prostatic biopsies are necessary in all men aged ≥80 years, as men found to have prostate cancer are frequently treated with a…”
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COX-2 Inhibition: A Possible Role in the Management of Prostate Cancer? by Sooriakumaran, P., Langley, S.E.M., Laing, R.W., Coley, H.M.

“…There is mounting evidence to support a role for cyclooxygenase-2 (COX-2) inhibitors (coxibs) in the management of prostate cancer. This review considers the…”
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Correlation between prostate brachytherapy-related urethral stricture and peri-apical urethral dosimetry: A matched case–control study by Earley, James J, Abdelbaky, Ather M, Cunningham, Melanie J, Chadwick, Eliot, Langley, Stephen E.M, Laing, Robert W

“…Abstract Background and purpose Radiation dose to the bulbomembranous urethra has been shown to correlate with urethral stricture formation. This retrospective…”
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Low‐dose‐rate brachytherapy for the treatment of localised prostate cancer in men with a high risk of disease relapse by Laing, Robert, Uribe, Jennifer, Uribe‐Lewis, Santiago, Money‐Kyrle, Julian, Perna, Carla, Chintzoglou, Stylianos, Khaksar, Sara, Langley, Stephen E.M.

“…Objectives To report clinical outcomes of 125I low‐dose‐rate prostate brachytherapy (LDR‐PB) as monotherapy or combined with androgen‐deprivation therapy (ADT)…”
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Comparative Analysis of Clinical Outcomes and Procedural Costs between the Conventional Two-stage Technique and 4D Brachytherapy for Early Prostate Cancer by Langley, S.E.M., Uribe, J., Uribe-Lewis, S., Money-Kyrle, J., Perna, C., Khaksar, S., Soares, R., Laing, R.

“…To assess long-term outcomes and resource use of 4D Brachytherapy, a one-stage real-time implant for the treatment of prostate cancer that uses stranded and…”
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Metabolic Syndrome and Prostate Cancer: A Review by Nobes, J.P, Langley, S.E.M, Laing, R.W

“…Abstract Androgen deprivation therapy is widely used in a number of different settings in the treatment of prostate cancer. This overview will look at the…”
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