Search Results - "Langlais, P J"
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1
Neurotransmitters in basal ganglia and cortex of Alzheimer's disease with and without Lewy bodies
Published in Neurology (01-10-1993)“…We measured the concentrations of the monoamines, their precursors, and their metabolites, and the activity of choline acetyltransferase (ChAT) in basal…”
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2
Learning and Memory in Rape Victims With Posttraumatic Stress Disorder
Published in The American journal of psychiatry (01-02-1998)“…OBJECTIVE: Studies have shown memory deficits among combat veterans with posttraumatic stress disorder (PTSD); however, high rates of comorbid conditions,…”
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3
Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease
Published in The Journal of neuroscience (01-03-1994)“…We have examined several aspects of neurotransmitter function in the brains of mice carrying a deletion mutation in the gene encoding the purine salvage enzyme…”
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4
Grafting Fibroblasts Genetically Modified to Produce L-Dopa in a Rat Model of Parkinson Disease
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1989)“…Rat fibroblasts were infected with a retroviral vector containing the cDNA for rat tyrosine hydroxylase [TH; tyrosine 3-monooxygenase; L-tyrosine,…”
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5
Protective effects of the glutamate antagonist MK-801 on pyrithiamine- induced lesions and amino acid changes in rat brain
Published in The Journal of neuroscience (01-05-1990)“…An acute bout of pyrithiamine-induced thiamine deficiency (PTD) produces pathologic lesions within thalamus, mammillary body, and periventricular regions of…”
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6
An examination of the synergistic interaction of ethanol and thiamine deficiency in the development of neurological signs and long-term cognitive and memory impairments
Published in Alcoholism, clinical and experimental research (01-05-2000)“…The prolonged and heavy consumption of ethanol has been associated with thiamine deficiency and a wide range of cognitive and memory impairments. The present…”
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7
Functional analysis of brain dopamine systems in a genetic mouse model of Lesch-Nyhan syndrome
Published in The Journal of pharmacology and experimental therapeutics (01-11-1992)“…The Lesch-Nyhan syndrome is a neurogenetic disorder caused by congenital deficiency of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase…”
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8
Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801
Published in Journal of neurochemistry (01-12-1993)“…The current study measured extracellular fluid (ECF) levels of excitatory amino acids before and during the onset of thiamine deficiency-induced pathologic…”
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9
Cortical and Subcortical White Matter Damage without Wernicke's Encephalopathy after Recovery from Thiamine Deficiency in the Rat
Published in Alcoholism, clinical and experimental research (01-05-1997)“…The relative etiologic roles of ethanol and thiamine deficiency in the cortical atrophy and loss of cerebral white matter in chronic alcoholics are uncertain…”
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10
Thiamine deficiency-induced disruptions in the diurnal rhythm and regulation of body temperature in the rat
Published in Metabolic brain disease (01-09-1998)“…In the present study, diurnal rhythm and regulation of body temperature were monitored during and several weeks following pyrithiamine-induced thiamine…”
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11
Increased cerebral free radical production during thiamine deficiency
Published in Metabolic brain disease (01-06-1997)“…Concentration of reactive oxygen species (ROS) and the antioxidant glutathione (GSH) was measured in thalamus and cortex after 13 and 14 days of…”
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12
Excitotoxic cytopathology, progression, and reversibility of thiamine deficiency-induced diencephalic lesions
Published in Journal of neuropathology and experimental neurology (01-03-1995)“…The present study examined the cytopathological changes within diencephalon of a rat model of Wernicke's encephalopathy and determined whether administration…”
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13
The effects of lesions to thalamic lateral internal medullary lamina and posterior nuclei on learning, memory and habituation in the rat
Published in Behavioural brain research (1997)“…The behavioral effects of radiofrequency lesions to the lateral internal medullary lamina region (IML) or the posterior region (Po: containing the…”
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14
Effects of Lesions of Thalamic Intralaminar and Midline Nuclei and Internal Medullary Lamina on Spatial Memory and Object Discrimination
Published in Behavioral neuroscience (01-12-1998)“…Male Sprague-Dawley rats received either radiofrequency lesions of the lateral internal medullary lamina (IML) or ibotenic acid lesions of the lateral…”
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15
Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy
Published in Journal of neuroscience research (01-08-1994)“…Three experiments were conducted to examine the role of histamine in neuronal degeneration in a rat model of Wernicke's encephalopathy induced by an acute bout…”
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16
Dopamine beta-hydroxylase immunoreactivity in human cerebrospinal fluid: properties, relationship to central noradrenergic neuronal activity and variation in Parkinson's disease and congenital dopamine beta-hydroxylase deficiency
Published in Clinical science (1979) (01-02-1994)“…1. Dopamine beta-hydroxylase is stored and released with catecholamines by exocytosis from secretory vesicles in noradrenergic neurons and chromaffin cells…”
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Behavioral impairments after lesions of the nucleus basalis by ibotenic acid and quisqualic acid
Published in Brain research (26-07-1991)“…Ibotenic acid (IBO) or quisqualic acid (QUIS) was infused into the region of the nucleus basalis magnocellularis (NBm) in F344 rats in order to behaviorally…”
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18
Increased histamine release and granulocytes within the thalamus of a rat model of Wernicke's encephalopathy
Published in Brain research (10-03-2000)“…The current study examined the possible role of increased histamine release and granulocyte activity in the vascular changes that precede the onset of necrotic…”
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19
Pathogenesis of diencephalic lesions in an experimental model of Wernicke's encephalopathy
Published in Metabolic brain disease (01-03-1995)“…The relationship of thiamine deficiency to Wernicke's encephalopathy has been well established. The biochemical bases and physiologic mechanisms responsible…”
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Conference Proceeding Journal Article -
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Increased Mast Cell Degranulation within Thalamus in Early Pre-lesion Stages of an Experimental Model of Wernickeʼs Encephalopathy
Published in Journal of neuropathology and experimental neurology (01-07-1999)“…A large increase in the number and percentage of degranulating mast cells was observed within thalamus of rats after 6-7 days of thiaminc deficiency (TD). No…”
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