Search Results - "Langguth, Emma"

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    FcRγ Gene Editing Reprograms Conventional NK Cells to Display Key Features of Adaptive Human NK Cells

    FcRγ Gene Editing Reprograms Conventional NK Cells to Display Key Features of Adaptive Human NK Cells by Liu, Weiru, Scott, Jeannine M., Langguth, Emma, Chang, Helena, Park, Peter H., Kim, Sungjin

    Published in iScience (20-11-2020)
    “…Adaptive human natural killer (NK) cells display significantly enhanced responsiveness to a broad-range of antibody-bound targets through the engagement of…”
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    An arrayed CRISPR screen reveals Myc depletion to increase productivity of difficult-to-express complex antibodies in CHO cells

    An arrayed CRISPR screen reveals Myc depletion to increase productivity of difficult-to-express complex antibodies in CHO cells by Bauer, Niels, Oswald, Benedikt, Eiche, Maximilian, Schiller, Lisa, Langguth, Emma, Schantz, Christian, Osterlehner, Andrea, Shen, Amy, Misaghi, Shahram, Stingele, Julian, Ausländer, Simon

    “…Abstract Complex therapeutic antibody formats, such as bispecifics (bsAbs) or cytokine fusions, may provide new treatment options in diverse disease areas…”
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