Search Results - "Langeveld, Simone A."

Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers by Langeveld, Simone A. G, Schwieger, Christian, Beekers, Inés, Blaffert, Jacob, van Rooij, Tom, Blume, Alfred, Kooiman, Klazina

“…Phospholipid-coated targeted microbubbles are ultrasound contrast agents that can be used for molecular imaging and enhanced drug delivery. However, a better…”
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Phospholipid-coated targeted microbubbles for ultrasound molecular imaging and therapy by Langeveld, Simone A.G., Meijlink, Bram, Kooiman, Klazina

“…Phospholipid-coated microbubbles are ultrasound contrast agents that, when functionalized, adhere to specific biomarkers on cells. In this concise review, we…”
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Theranostic Microbubbles with Homogeneous Ligand Distribution for Higher Binding Efficacy by Langeveld, Simone A G, Meijlink, Bram, Beekers, Inés, Olthof, Mark, van der Steen, Antonius F W, de Jong, Nico, Kooiman, Klazina

“…Phospholipid-coated targeted microbubbles are used for ultrasound molecular imaging and locally enhanced drug delivery, with the binding efficacy being an…”
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Dispersing and Sonoporating Biofilm-Associated Bacteria with Sonobactericide by Lattwein, Kirby R, Beekers, Inés, Kouijzer, Joop J P, Leon-Grooters, Mariël, Langeveld, Simone A G, van Rooij, Tom, van der Steen, Antonius F W, de Jong, Nico, van Wamel, Willem J B, Kooiman, Klazina

“…Bacteria encased in a biofilm poses significant challenges to successful treatment, since both the immune system and antibiotics are ineffective…”
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Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels by Beekers, Inés, Langeveld, Simone A.G., Meijlink, Bram, van der Steen, Antonius F.W., de Jong, Nico, Verweij, Martin D., Kooiman, Klazina

“…Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing the cell membrane permeability. To aid development of a safe and…”
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In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells by Laksono, Brigitta M, Grosserichter-Wagener, Christina, de Vries, Rory D, Langeveld, Simone A G, Brem, Maarten D, van Dongen, Jacques J M, Katsikis, Peter D, Koopmans, Marion P G, van Zelm, Menno C, de Swart, Rik L

“…Measles is characterized by a transient immune suppression, leading to an increased risk of opportunistic infections. Measles virus (MV) infection of immune…”
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Ultrasonic Characterization of Ibidi μ-Slide I Luer Channel Slides for Studies With Ultrasound Contrast Agents by Pakdaman Zangabad, Reza, Li, Hongchen, Kouijzer, Joop J. P., Langeveld, Simone A. G., Beekers, Ines, Verweij, Martin, De Jong, Nico, Kooiman, Klazina

“…Understanding and controlling the ultrasound contrast agent (UCA)'s response to an applied ultrasound pressure field are crucial when investigating ultrasound…”
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Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery by Kooiman, Klazina, Roovers, Silke, Langeveld, Simone A.G., Kleven, Robert T., Dewitte, Heleen, O'Reilly, Meaghan A., Escoffre, Jean-Michel, Bouakaz, Ayache, Verweij, Martin D., Hynynen, Kullervo, Lentacker, Ine, Stride, Eleanor, Holland, Christy K.

“…Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for beneficial tissue bio-effects are actively under development…”
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Vancomycin-decorated microbubbles as a theranostic agent for Staphylococcus aureus biofilms by Kouijzer, Joop J.P., Lattwein, Kirby R., Beekers, Inés, Langeveld, Simone A.G., Leon-Grooters, Mariël, Strub, Jean-Marc, Oliva, Estefania, Mislin, Gaëtan L.A., de Jong, Nico, van der Steen, Antonius F.W., Klibanov, Alexander L., van Wamel, Willem J.B., Kooiman, Klazina

“…[Display omitted] Bacterial biofilms are a huge burden on our healthcare systems worldwide. The lack of specificity in diagnostic and treatment possibilities…”
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Combined Confocal Microscope and Brandaris 128 Ultra-High-Speed Camera by Beekers, Inés, Lattwein, Kirby R., Kouijzer, Joop J.P., Langeveld, Simone A.G., Vegter, Merel, Beurskens, Robert, Mastik, Frits, Verduyn Lunel, Rogier, Verver, Emma, van der Steen, Antonius F.W., de Jong, Nico, Kooiman, Klazina

“…Controlling microbubble-mediated drug delivery requires the underlying biological and physical mechanisms to be unraveled. To image both microbubble…”
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The Impact of Lipid Handling and Phase Distribution on the Acoustic Behavior of Microbubbles by Langeveld, Simone A G, Beekers, Inés, Collado-Lara, Gonzalo, van der Steen, Antonius F W, de Jong, Nico, Kooiman, Klazina

“…Phospholipid-coated microbubbles are ultrasound contrast agents that can be employed for ultrasound molecular imaging and drug delivery. For safe and effective…”
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The spatial distribution of the ligand on targeted microbubbles influences the binding efficacy by Langeveld, Simone A. G., Meijlink, Bram, Beekers, Ines, Olthof, Mark, van der Steen, Antonius F., de Jong, Nico, Kooiman, Klazina

“…An important trait of targeted microbubbles is their binding to biomarkers for ultrasound molecular imaging and drug delivery. Using organic solvents in…”
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The OrganoPlate® as vessel-on-a-chip model to investigate increased microbubble-mediated vascular permeability by Meijlink, Bram, Beekers, Ines, Langeveld, Simone A. G., Bishard, Kristina, van der Steen, Antonius F., de Jong, Nico, Trietsch, Sebastiaan J., Kooiman, Klazina

“…The vessel wall is an important barrier modulating drug delivery to the underlying diseased tissue. Oscillating microbubbles can be used to locally enhance…”
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Microbubble-endothelial cell interactions in 3D: Internalization of microbubbles and pore or tunnel formation for drug delivery by Beekers, Ines, Langeveld, Simone A. G., Meijlink, Bram, van der Steen, Antonius F., de Jong, Nico, Verweij, Martin D., Kooiman, Klazina

“…Ultrasound-activated microbubbles can locally enhance vascular drug delivery, but fully understanding the mechanism requires further investigation. The aims of…”
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Phospholipid-coated microbubbles: Controlling response to ultrasound by Langeveld, Simone A., Beekers, Ines, van der Steen, Antonius F. W., de Jong, Nico, Kooiman, Klazina

“…Variability in response to ultrasound is an issue when microbubbles are used for drug delivery. This may be caused by immiscible phospholipid components and…”
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Lipid Phase Distribution and Acoustic Response of DSPE-based Microbubbles by Langeveld, Simone A.G., Collado-Lara, Gonzalo, Wiggers, Gerrit J. W., Van Der Steen, Antonius F.W., Jong, Nico De, Kooiman, Klazina

“…Microbubbles (MBs) are versatile ultrasound contrast agents that can be used for ultrasound molecular imaging and targeted drug delivery. However, a uniform…”
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Ultrasonic Characterization of Ibidi μ -Slide I Luer Channel Slides for Studies With Ultrasound Contrast Agents by Pakdaman Zangabad, Reza, Li, Hongchen, Kouijzer, Joop J. P, Langeveld, Simone A. G, Beekers, Ines, Verweij, Martin, De Jong, Nico, Kooiman, Klazina

“…Understanding and controlling the ultrasound contrast agent (UCA)'s response to an applied ultrasound pressure field are crucial when investigating ultrasound…”
Get full text