Search Results - "Langeveld, Jan P. M."
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Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt–Jakob disease: its effect on the phenotype and prion-type characteristics
Published in Brain (London, England : 1878) (01-10-2009)“…Five phenotypically distinct subtypes have been identified in sporadic Creutzfeldt–Jakob disease (sCJD), based on the methionine/valine polymorphic genotype of…”
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2
Stability of BSE infectivity towards heat treatment even after proteolytic removal of prion protein
Published in Veterinary research (Paris) (16-04-2021)“…The unconventional infectious agents of transmissible spongiform encephalopathies (TSEs) are prions. Their infectivity co-appears with PrP , aberrant…”
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Molecular Discrimination of Atypical Bovine Spongiform Encephalopathy Strains from a Geographical Region Spanning a Wide Area in Europe
Published in Journal of Clinical Microbiology (01-06-2007)“…Transmissible spongiform encephalopathy strains can be differentiated by their behavior in bioassays and by molecular analyses of the disease-associated prion…”
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4
Detection of prion protein particles in blood plasma of scrapie infected sheep
Published in PloS one (02-05-2012)“…Prion diseases are transmissible neurodegenerative diseases affecting humans and animals. The agent of the disease is the prion consisting mainly, if not…”
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Prion protein-specific antibodies that detect multiple TSE agents with high sensitivity
Published in PloS one (07-03-2014)“…This paper describes the generation, characterisation and potential applications of a panel of novel anti-prion protein monoclonal antibodies (mAbs). The mAbs…”
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Enhanced Virulence of Sheep-Passaged Bovine Spongiform Encephalopathy Agent Is Revealed by Decreased Polymorphism Barriers in Prion Protein Conversion Studies
Published in Journal of Virology (01-03-2014)“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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EU-approved rapid tests for bovine spongiform encephalopathy detect atypical forms: a study for their sensitivities
Published in PloS one (11-09-2012)“…Since 2004 it become clear that atypical bovine spongiform encephalopthies (BSEs) exist in cattle. Whenever their detection has relied on active surveillance…”
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Enzymatic Degradation of Prion Protein in Brain Stem from Infected Cattle and Sheep
Published in The Journal of infectious diseases (01-12-2003)“…Prions—infectious agents involved in transmissible spongiform encephalopathies—normally survive proteolytic and mild protein-destructive processes. Using…”
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Four Independent Molecular Prion Protein Parameters for Discriminating New Cases of C, L, and H Bovine Spongiform Encephalopathy in Cattle
Published in Journal of Clinical Microbiology (01-08-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification
Published in Acta neuropathologica (01-11-2009)“…Six subtypes of sporadic Creutzfeldt–Jakob disease with distinctive clinico-pathological features have been identified largely based on two types of the…”
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Distinct Proteinase K-Resistant Prion Protein Fragment in Goats with No Signs of Disease in a Classical Scrapie Outbreak
Published in Journal of Clinical Microbiology (01-06-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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12
Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain
Published in Annals of neurology (01-03-2009)“…Objective Variant Creutzfeldt–Jakob disease (vCJD) was first reported in the United Kingdom in 1996. Since then, the majority of cases have been observed in…”
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A novel recombinant virus-like particle vaccine for prevention of porcine parvovirus-induced reproductive failure
Published in Vaccine (29-06-2006)“…A novel vaccine against porcine parvovirus (PPV), composed of recombinant virus-like particles (PPV-VLPs) produced with the baculovirus expression vector…”
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Characterization of goat prions demonstrates geographical variation of scrapie strains in Europe and reveals the composite nature of prion strains
Published in Scientific reports (08-01-2020)“…Bovine Spongiform Encephalopathy (BSE) is the only animal prion which has been recognized as a zoonotic agent so far. The identification of BSE in two goats…”
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15
Prion protein self-interactions: A gateway to novel therapeutic strategies?
Published in Vaccine (16-11-2010)“…Abstract Transmissible spongiform encephalopathies (TSEs) or prion diseases are fatal neurodegenerative disorders and include among others Creutzfeldt–Jakob…”
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Four types of scrapie in goats differentiated from each other and bovine spongiform encephalopathy by biochemical methods
Published in Veterinary research (Paris) (25-11-2019)“…Scrapie in goats has been known since 1942, the archetype of prion diseases in which only prion protein (PrP) in misfolded state (PrP ) acts as infectious…”
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Polymorphisms of Codons 110, 146, 211 and 222 at the Goat PRNP Locus and Their Association with Scrapie in Greece
Published in Animals (Basel) (08-08-2021)“…Scrapie is considered an endemic disease in both sheep and goats in Greece. However, contrary to sheep, in goats more than one prion protein (PrP) polymorphism…”
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Further Characterization of Glycoform-Selective Prions of Variably Protease-Sensitive Prionopathy
Published in Pathogens (Basel) (23-04-2021)“…Prion is an infectious protein (PrP ) that is derived from a cellular glycoprotein (PrP ) through a conformational transition and associated with a group of…”
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Characterization of Truncated Forms of Abnormal Prion Protein in Creutzfeldt-Jakob Disease
Published in The Journal of biological chemistry (07-11-2008)“…In prion disease, the abnormal conformer of the cellular prion protein, PrPSc, deposits in fibrillar protein aggregates in brain and other organs. Limited…”
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Scrapie incidence and PRNP polymorphisms: rare small ruminant breeds of Sicily with TSE protecting genetic reservoirs
Published in BMC veterinary research (15-07-2016)“…Transmissible spongiform encephalopathies (TSE) are fatal neurodegenerative diseases of several mammalian species, including humans. In Italy, the active…”
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