Search Results - "Langeveld, J P M"

Protecting effect of PrP codons M142 and K222 in goats orally challenged with bovine spongiform encephalopathy prions by Fast, C, Goldmann, W, Berthon, P, Tauscher, K, Andréoletti, O, Lantier, I, Rossignol, C, Bossers, A, Jacobs, J G, Hunter, N, Groschup, M H, Lantier, F, Langeveld, J P M

“…Breeding towards genetic resistance to prion disease is effective in eliminating scrapie. In sheep, classical forms of scrapie have been eradicated almost…”
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Proteinase K-Resistant Material in ARR/VRQ Sheep Brain Affected with Classical Scrapie Is Composed Mainly of VRQ Prion Protein by Jacobs, J. G, Bossers, A, Rezaei, H, van Keulen, L. J. M, McCutcheon, S, Sklaviadis, T, Lantier, I, Berthon, P, Lantier, F, van Zijderveld, F. G, Langeveld, J. P. M

“…Classical scrapie is a prion disease in sheep and goats. In sheep, susceptibility to disease is genetically influenced by single amino acid substitutions…”
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Discrimination between Scrapie and Bovine Spongiform Encephalopathy in Sheep by Molecular Size, Immunoreactivity, and Glycoprofile of Prion Protein by THURING, C. M. A, ERKENS, J. H. F, LANGEVELD, J. P. M, JACOBS, J. G, BOSSERS, A, VAN KEULEN, L. J. M, GARSSEN, G. J, VAN ZIJDERVELD, F. G, RYDER, S. J, GROSCHUP, M. H, SWEENEY, T

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Atypical status of bovine spongiform encephalopathy in Poland: a molecular typing study by Polak, M. P, Zmudzinski, J. F, Jacobs, J. G, Langeveld, J. P. M

“…The aim of this study was to analyze molecular features of protease-resistant prion protein (PrPres) in Western blots of BSE cases diagnosed in Poland with…”
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Prion Type-Dependent Deposition of PRNP Allelic Products in Heterozygous Sheep by Langeveld, J P M, Jacobs, J G, Hunter, N, van Keulen, L J M, Lantier, F, van Zijderveld, F G, Bossers, A

“…Susceptibility or resistance to prion infection in humans and animals depends on single prion protein (PrP) amino acid substitutions in the host, but the…”
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Variation in the prion protein sequence in Dutch goat breeds by Windig, J.J., Hoving, R.A.H., Priem, J., Bossers, A., van Keulen, L.J.M., Langeveld, J.P.M.

“…Summary Scrapie is a neurodegenerative disease occurring in goats and sheep. Several haplotypes of the prion protein increase resistance to scrapie infection…”
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Preclinical test for prion diseases by Schreuder, B. E. C, van Keulen, L. J. M, Vromans, M. E. W, Langeveld, J. P. M, Smits, M. A

“…Here we suggest a possible approach to an early preclinical diagnostic method for transmissible spongiform encephalopathies using scrapie in sheep as a model…”
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Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie by JACOBS, J. G, SAUER, M, VAN KEULEN, L. J. M, TANG, Y, BOSSERS, A, LANGEVEID, J. P. M

“…With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the…”
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Evaluation of two commercial, rapid, ELISA kits testing for scrapie in retro-pharyngeal lymph nodes in sheep by Kittelberger, R, McIntyre, L, Watts, J, MacDiarmid, S, Hannah, MJ, Jenner, J, Bueno, R, Swainsbury, R, Langeveld, JPM, van Keulen, LJM, van Zijderveld, FG, Wemheuer, WM, Richt, JA, Sorensen, SJ, Pigott, CJ, O'Keefe, JS

“…AIMS: To estimate the number of cases of scrapie that would occur in sheep of different prion protein (PrP) genotypes if scrapie was to become established in…”
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Tonsillar biopsy and PrPSc detection in the preclinical diagnosis of scrapie by Schreuder, B. E. C., van Keulen, L. J. M., Vromans, M. E. W., Langeveld, J. P. M., Smits, M. A.

“…Preliminary findings have indicated that in naturally infected sheep, fully susceptible to scrapie (vRQ-homozygous), PrPSc can be detected in the tonsils…”
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Epitopes on glycoprotein E and on the glycoprotein E/glycoprotein I complex of bovine herpesvirus 1 are expressed by all of 222 isolates and 11 vaccine strains by RIJSEWIJK, F. A. M, KAASHOEK, M. J, LANGEVELD, J. P. M, MARIS-VELDHUIS, M. A, MAGDALENA, J, VERSCHUREN, S. B. E, MELOEN, R. H, VAN OIRSCHOT, J. T

“…Glycoprotein E (gE) of bovine herpesvirus 1 (BHV1) forms a complex with glycoprotein I (gI) and plays an important role in cell-to-cell spread mechanisms of…”
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Large scale production and downstream processing of a recombinant porcine parvovirus vaccine by Maranga, L, Rueda, P, Antonis, A.F.G, Vela, C, Langeveld, J.P.M, Casal, J.I, Carrondo, M.J.T

“…Porcine parvovirus (PPV) virus-like particles (VLPs) constitute a potential vaccine for prevention of parvovirus-induced reproductive failure in gilts. Here we…”
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Immunohistochemical evaluation of tonsillar tissue for preclinical screening of scrapie based on surveillance in Belgium by Roels, S., Vanopdenbosch, E., Langeveld, J. P. M., Schreuder, B. E. C.

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TSE strain differentiation in mice by immunohistochemical PrPSc profiles and triplex Western blot by van Keulen, Lucien J. M., Langeveld, Jan P. M., Dolstra, Corry H., Jacobs, Jorg, Bossers, Alex, van Zijderveld, Fred G.

“…TSE strains are routinely identified by their incubation period and vacuolation profile in the brain after intracerebral inoculation and serial passaging in…”
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Variability in disease phenotypes within a single PRNP genotype suggests the existence of multiple natural sheep scrapie strains within Europe by GONZALEZ, Lorenzo, SISO, Silvia, BADIOLA, Juan J, JEFFREY, Martin, ACIN, Cristina, MONLEON, Eva, CASALONE, Cristina, VAN KEULEN, Lucien J. M, BALKEMA-BUSCHMANN, Anne, ORTIZ-PELAEZ, Angel, IULINI, Barbara, LANGEVELD, Jan P. M, HOFFMANN, Christine

“…Variability of pathological phenotypes within classical sheep scrapie cases has been reported for some time, but in many instances it has been attributed to…”
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Immunohistochemical features of PrP(d) accumulation in natural and experimental goat transmissible spongiform encephalopathies by Jeffrey, M, Martin, S, González, L, Foster, J, Langeveld, J P M, van Zijderveld, F G, Grassi, J, Hunter, N

“…Scrapie is a transmissible spongiform encephalopathy (TSE) or prion disease, which naturally affects sheep and goats. Immunohistochemical epitope mapping of…”
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Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie by Keulen, L.J.M. van (Institute for Animal Science and Health, Lelystad, The Netherlands.), Schreuder, B.E.C, Meloen, R.H, Mooij-Harkes, G, Vromans, M.E.W, Langeveld, J.P.M

“…The scrapie-associated form of the prion protein (PrPSc) accumulates in the brain and lymphoid tissues of sheep with scrapie. In order to assess whether…”
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Oral immunisation of naive and primed animals with transgenic potato tubers expressing LT-B by Lauterslager, T.G.M, Florack, D.E.A, van der Wal, T.J, Molthoff, J.W, Langeveld, J.P.M, Bosch, D, Boersma, W.J.A, Hilgers, L.A.Th

“…The efficacy of edible vaccines produced in potato tubers was examined in mice. Transgenic plants were developed by Agrobacterium tumefaciens-mediated…”
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Plant-derived vaccine protects target animals against a viral disease by Dalsgaard, K. (Danish Veterinary Institute for Virus Research, Kalvehave, Denmark.), Uttenthal, A, Jones, T.D, Xu, F, Merryweather, A, Hamilton, W.D.O, Langeveld, J.P.M, Boshuizen, R.S, Kamstrup, S, Lomonossoff, G.P

“…The successful expression of animal or human virus epitopes on the surface of plant viruses has recently been demonstrated. These chimeric virus particles…”
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Immunohistochemical Distinction between Preclinical Bovine Spongiform Encephalopathy and Scrapie Infection in Sheep by Thuring, C.M.A., van Keulen, L.J.M., Langeveld, J.P.M., Vromans, M.E.W., van Zijderveld, F.G., Sweeney, T.

“…Sheep are susceptible experimentally to bovine spongiform encephalopathy (BSE), the clinical signs being indistinguishable from those of scrapie. Because of…”
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