Search Results - "Langer, Simone"

Flavoproteins Are Potential Targets for the Antibiotic Roseoflavin in Escherichia coli by Langer, Simone, Hashimoto, Masayuki, Hobl, Birgit, Mathes, Tilo, Mack, Matthias

“…The riboflavin analog roseoflavin is an antibiotic produced by Streptomyces davawensis. Riboflavin transporters are responsible for roseoflavin uptake by…”
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Riboflavin analogs as antiinfectives: occurrence, mode of action, metabolism and resistance by Pedrolli, Danielle Biscaro, Jankowitsch, Frank, Schwarz, Julia, Langer, Simone, Nakanishi, Shinobu, Frei, Eva, Mack, Matthias

“…Antimetabolites are molecules, which are structurally similar to molecules needed to carry out primary metabolic reactions.The inhibitory activity of an…”
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ribB FMN riboswitch from Escherichia coli operates at the transcriptional and translational level and regulates riboflavin biosynthesis by Pedrolli, Danielle, Langer, Simone, Hobl, Birgit, Schwarz, Julia, Hashimoto, Masayuki, Mack, Matthias

“…FMN riboswitches are genetic elements that, in many bacteria, control genes responsible for biosynthesis and/or transport of riboflavin (vitamin B₂). We report…”
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The Flavoenzyme Azobenzene Reductase AzoR from Escherichia coli Binds Roseoflavin Mononucleotide (RoFMN) with High Affinity and Is Less Active in Its RoFMN Form by Langer, Simone, Nakanishi, Shinobu, Mathes, Tilo, Knaus, Tanja, Binter, Alexandra, Macheroux, Peter, Mase, Tomoko, Miyakawa, Takuya, Tanokura, Masaru, Mack, Matthias

“…The Gram-positive bacterium Streptomyces davawensis is the only organism known to produce the antibiotic roseoflavin. Roseoflavin is a structural riboflavin…”
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Natural riboflavin analogs by Pedrolli, Danielle Biscaro, Jankowitsch, Frank, Schwarz, Julia, Langer, Simone, Nakanishi, Shinobu, Mack, Matthias

“…Riboflavin analogs have a good potential to serve as basic structures for the development of novel anti-infectives. Riboflavin analogs have multiple cellular…”
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